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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
hand2 and Dlx genes specify dorsal, intermediate and ventral domains within zebrafish pharyngeal arches
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Citation:
Development. 2010 Aug 1;137(15):2507-17. Epub 2010 Jun 23 Epub:
Not Epub Abstract:
The ventrally expressed secreted polypeptide endothelin1 (Edn1) patterns the skeleton derived from the first two pharyngeal... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Talbot JC, Johnson SL, Kimmel CB. hand2 and Dlx genes specify dorsal, intermediate and ventral domains within zebrafish pharyngeal arches. Development. 2010 Aug 1;137(15):2507-17. Epub 2010 Jun 23. |
Hedgehog signalling maintains the optic stalk-retinal interface through the regulation of Vax gene activity
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Citation:
Development. 2003 Mar;130(5):955-68 Epub:
Not Epub Abstract:
During early formation of the eye, the optic vesicle becomes partitioned into a proximal domain that forms the optic nerve and... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Take-uchi M, Clarke JD, Wilson SW. Hedgehog signalling maintains the optic stalk-retinal interface through the regulation of Vax gene activity. Development. 2003 Mar;130(5):955-68. |
Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections
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Citation:
Cell. 2012 Feb 3;148(3):434-46. doi: 10.1016/j.cell.2011.12.023 Epub:
Not Epub Abstract:
Susceptibility to tuberculosis is historically ascribed to an inadequate immune response that fails to control infecting... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Tobin DM, Roca FJ, Oh SF, McFarland R, Vickery TW, Ray JP, Ko DC, Zou Y, Bang ND, Chau TT, Vary JC, Hawn TR, Dunstan SJ, Farrar JJ, Thwaites GE, King MC, Serhan CN, Ramakrishnan L. Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections. Cell. 2012 Feb 3;148(3):434-46. doi: 10.1016/j.cell.2011.12.023. |
Identification of membrane progestin receptors (mPR) in goldfish oocytes as a key mediator of steroid non-genomic action
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Citation:
Steroids. 2012 Apr 14. [Epub ahead of print] Epub:
Not Epub Abstract:
One of the most extensively investigated and well characterized models of non-genomic steroid actions initiated at the cell... Delivery Method:
Microinjection Organism or Cell Type:
Goldfish (Carassius auratus auratus) Citation Extract: Tokumoto T. Identification of membrane progestin receptors (mPR) in goldfish oocytes as a key mediator of steroid non-genomic action. Steroids. 2012 Apr 14. [Epub ahead of print]. |
Identification of target genes for the Xenopus Hes-related protein XHR1, a prepattern factor specifying the midbrain-hindbrain boundary
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Citation:
Dev Biol. 2005 Jul 1;283(1):253-67. Epub:
Not Epub Abstract:
The midbrain-hindbrain boundary (MHB) acts as a local organizer in the development of the CNS in vertebrates. Previously, we... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Takada H, Hattori D, Kitayama A, Ueno N, Taira M. Identification of target genes for the Xenopus Hes-related protein XHR1, a prepattern factor specifying the midbrain-hindbrain boundary. Dev Biol. 2005 Jul 1;283(1):253-67.. |
In vitro efficacy of morpholino-modified antisense oligomers directed against tumor necrosis factor-alpha mRNA
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Citation:
J Biol Chem. 1996 Jul 19;271(29):17445-52 Epub:
Not Epub Abstract:
Chemical modification of antisense oligonucleotides to increase nuclease resistance may improve their efficacy within enzyme-... Delivery Method:
culture: Incubation & free uptake Organism or Cell Type:
cell culture: RAW 264.7 cells Citation Extract: Taylor MF, Paulauskis JD, Weller DD, Kobzik L. In vitro efficacy of morpholino-modified antisense oligomers directed against tumor necrosis factor-alpha mRNA. J Biol Chem. 1996 Jul 19;271(29):17445-52. |
In vivo Electroporation of Morpholinos into the Adult Zebrafish Retina
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Citation:
J Vis Exp. 2011;58:e3603, doi:10.3791/3603 Epub:
Not Epub Abstract:
The adult zebrafish retina possesses a robust regenerative response. In the light-damaged retina, Müller glial cell divisions... Delivery Method:
Electroporation Organism or Cell Type:
zebrafish Citation Extract: Thummel R, Bailey TJ, Hyde DR. In vivo Electroporation of Morpholinos into the Adult Zebrafish Retina. J Vis Exp. 2011;58:e3603, doi:10.3791/3603. |
Induction of cytochrome P450 1A is required for circulation failure and edema by 2,3,7,8-tetrachlorodibenzo-p-dioxin in zebrafish.
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Citation:
Biochem Biophys Res Commun 2003 May 2;304(2):223-8 Epub:
Not Epub Abstract:
The mechanism of toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is thought to result from changes in gene expression... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Teraoka H, Dong W, Tsujimoto Y, Iwasa H, Endoh D, Ueno N, Stegeman JJ, Peterson RE, Hiraga T. Induction of cytochrome P450 1A is required for circulation failure and edema by 2,3,7,8-tetrachlorodibenzo-p-dioxin in zebrafish.. Biochem Biophys Res Commun 2003 May 2;304(2):223-8. |
Inhibition of Müller glial cell division blocks regeneration of the light-damaged zebrafish retina
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Citation:
Dev Neurobiol. 2008 Feb 15;68(3):392-408. Epub:
Not Epub Abstract:
The adult zebrafish retina possesses a robust regenerative response. In the light-damaged retina, Müller glial cell divisions... Delivery Method:
in vivo: injection then electroporation Organism or Cell Type:
zebrafish Citation Extract: Thummel R, Kassen SC, Montgomery JE, Enright JM, Hyde DR. Inhibition of Müller glial cell division blocks regeneration of the light-damaged zebrafish retina. Dev Neurobiol. 2008 Feb 15;68(3):392-408.. |
Inhibition of neural crest migration underlies craniofacial dysmorphology and Hirschsprung's disease in Bardet-Biedl syndrome
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Citation:
Proc Natl Acad Sci U S A. 2008 May 6;105(18):6714-9. Epub 2008 Apr 28. Epub:
Not Epub Abstract:
Facial recognition is central to the diagnosis of many syndromes, and craniofacial patterns may reflect common etiologies. In... Organism or Cell Type:
zebrafish Citation Extract: Tobin JL, Di Franco M, Eichers E, May-Simera H, Garcia M, Yan J, Quinlan R, Justice MJ, Hennekam RC, Briscoe J, Tada M, Mayor R, Burns AJ, Lupski JR, Hammond P, Beales PL. Inhibition of neural crest migration underlies craniofacial dysmorphology and Hirschsprung's disease in Bardet-Biedl syndrome. Proc Natl Acad Sci U S A. 2008 May 6;105(18):6714-9. Epub 2008 Apr 28.. |