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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

In Vivo Conditions to Identify Prkci Phosphorylation Targets Using the Analog-Sensitive Kinase Method in Zebrafish

Authors:
Uhalte EC, Kirchner M, Hellwig N, Allen JJ, Donat S, Shokat KM, Selbach M, Abdelilah-Seyfried S
Citation:
PLoS One. 2012 June 29;7(6): e40000. doi: 10.1371/journal.pone.0040000
Epub:
Not Epub
Abstract:
Protein kinase C iota is required for various cell biological processes including epithelial tissue polarity and organ...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Uhalte EC, Kirchner M, Hellwig N, Allen JJ, Donat S, Shokat KM, Selbach M, Abdelilah-Seyfried S. In Vivo Conditions to Identify Prkci Phosphorylation Targets Using the Analog-Sensitive Kinase Method in Zebrafish. PLoS One. 2012 June 29;7(6): e40000. doi: 10.1371/journal.pone.0040000.

Inhibition of oct4 expression in mouse preimplantation embryos using morpholino antisense oligonucleotides

Authors:
Tsuji I, Mitani T, Mitsuhashi A, Watanabe Y, Hosoi Y, Hoshiai H
Citation:
Tohoku J Exp Med. 2006 Apr;208(4):333-42
Epub:
Not Epub
Abstract:
Morpholino oligonucleotides (MO) can induce gene silencing by binding to a target mRNA and inhibiting its translation, and this...
Delivery Method:
Special Delivery
Organism or Cell Type:
mouse embryos,preimplantation
Citation Extract:
Tsuji I, Mitani T, Mitsuhashi A, Watanabe Y, Hosoi Y, Hoshiai H. Inhibition of oct4 expression in mouse preimplantation embryos using morpholino antisense oligonucleotides. Tohoku J Exp Med. 2006 Apr;208(4):333-42.

Involvement of the eukaryotic initiation factor 6 and kermit2/gipc2 in Xenopus laevis pronephros formation

Authors:
Tussellino M, de Marco N, Campanella C, Carotenuto R
Citation:
Int J Dev Biol. 2012;[Epub ahead of print] doi: 10.1387/ijdb.120009nd
Epub:
Not Epub
Abstract:
The translation initiation factor Eif6 has been implicated as a regulator of ribosome assembly, selective mRNA translation and...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Tussellino M, de Marco N, Campanella C, Carotenuto R. Involvement of the eukaryotic initiation factor 6 and kermit2/gipc2 in Xenopus laevis pronephros formation. Int J Dev Biol. 2012;[Epub ahead of print] doi: 10.1387/ijdb.120009nd.

KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development

Authors:
Tsukada Y, Ishitani T, Nakayama KI
Citation:
Genes Dev. 2010 Mar 1;24(5):432-7
Epub:
Not Epub
Abstract:
Methylation of histone H3 Lys 9 and Lys 27 (H3K9 and H3K27) is associated with transcriptional silencing. Here we show that...
Organism or Cell Type:
zebrafish
Citation Extract:
Tsukada Y, Ishitani T, Nakayama KI. KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development. Genes Dev. 2010 Mar 1;24(5):432-7.

Lrrn1 is required for formation of the midbrain-hindbrain boundary and organiser through regulation of affinity differences between midbrain and hindbrain cells in chick

Authors:
Tossell K, Andreae LC, Cudmore C, Lang E, Muthukrishnan U, Lumsden A, Gilthorpe JD, Irving C
Citation:
Dev Biol. 2011 Apr 15;352(2):341-52. Epub 2011 Feb 18
Epub:
Not Epub
Abstract:
The midbrain-hindbrain boundary (MHB) acts as an organiser/signalling centre to pattern tectal and cerebellar compartments....
Delivery Method:
Electroporation
Organism or Cell Type:
chick embryo
Citation Extract:
Tossell K, Andreae LC, Cudmore C, Lang E, Muthukrishnan U, Lumsden A, Gilthorpe JD, Irving C. Lrrn1 is required for formation of the midbrain-hindbrain boundary and organiser through regulation of affinity differences between midbrain and hindbrain cells in chick. Dev Biol. 2011 Apr 15;352(2):341-52. Epub 2011 Feb 18.

Mechanism of positioning the cell nucleus in vertebrate photoreceptors

Authors:
Tsujikawa M, Omori Y, Biyanwila J, Malicki J
Citation:
Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14819-24. Epub 2007 Sep 4
Epub:
Not Epub
Abstract:
Organelles are frequently distributed in a nonrandom manner in a cell's cytoplasm. A particular distribution pattern often...
Organism or Cell Type:
zebrafish
Citation Extract:
Tsujikawa M, Omori Y, Biyanwila J, Malicki J. Mechanism of positioning the cell nucleus in vertebrate photoreceptors. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14819-24. Epub 2007 Sep 4.

Medaka osmotic stress transcription factor 1b (Ostf1b/TSC22D3-2) triggers hyperosmotic responses of different ion transporters in medaka gill and human embryonic kidney cells via the JNK signalling pathway

Authors:
Tse WK, Lai KP, Takei Y
Citation:
Int J Biochem Cell Biol. 2011 Sep 1. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Eukaryotic cells undergo rapid regulatory processes to maintain cellular homeostasis upon osmotic stress. In fishes, gill...
Delivery Method:
Microinjection
Organism or Cell Type:
medaka embryos
Citation Extract:
Tse WK, Lai KP, Takei Y. Medaka osmotic stress transcription factor 1b (Ostf1b/TSC22D3-2) triggers hyperosmotic responses of different ion transporters in medaka gill and human embryonic kidney cells via the JNK signalling pathway. Int J Biochem Cell Biol. 2011 Sep 1. [Epub ahead of print].

Mlck1a is expressed in zebrafish thrombocytes and an essential component for thrombus formation

Authors:
Tournoij E, Weber GJ, Akkerman JW, de Groot PG, Zon LI, Moll FL, Schulte-Merker S
Citation:
J Thromb Haemost. 2009. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Summary Background: We have used the advantages of the zebrafish model system to demonstrate which of the vertebrate Myosin...
Organism or Cell Type:
zebrafish
Citation Extract:
Tournoij E, Weber GJ, Akkerman JW, de Groot PG, Zon LI, Moll FL, Schulte-Merker S. Mlck1a is expressed in zebrafish thrombocytes and an essential component for thrombus formation. J Thromb Haemost. 2009. [Epub ahead of print].

Morpholino-mediated gene knockdown in Mammalian organ culture

Authors:
Tufro A
Citation:
Methods Mol Biol. 2012;886:305-9
Epub:
Not Epub
Abstract:
We examined the role of semaphorin3a in ureteric bud (UB) branching morphogenesis using mouse metanephric organ culture [Tufro...
Citation Extract:
Tufro A. Morpholino-mediated gene knockdown in Mammalian organ culture. Methods Mol Biol. 2012;886:305-9.

Mutations in multidomain protein MEGF8 identify a Carpenter syndrome subtype associated with defective lateralization

Authors:
Twigg SR, Lloyd D, Jenkins D, Elçioglu NE, Cooper CD, Al-Sannaa N, Annagür A, Gillessen-Kaesbach G, Hüning I, Knight SJ, Goodship JA, Keavney BD, Beales PL, Gileadi O, McGowan SJ, Wilkie AO
Citation:
Am J Hum Genet. 2012 Nov 2;91(5):897-905. doi: 10.1016/j.ajhg.2012.08.027. Epub 2012 Oct 11
Epub:
Not Epub
Abstract:
Carpenter syndrome is an autosomal-recessive multiple-congenital-malformation disorder characterized by multisuture...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Twigg SR, Lloyd D, Jenkins D, Elçioglu NE, Cooper CD, Al-Sannaa N, Annagür A, Gillessen-Kaesbach G, Hüning I, Knight SJ, Goodship JA, Keavney BD, Beales PL, Gileadi O, McGowan SJ, Wilkie AO. Mutations in multidomain protein MEGF8 identify a Carpenter syndrome subtype associated with defective lateralization. Am J Hum Genet. 2012 Nov 2;91(5):897-905. doi: 10.1016/j.ajhg.2012.08.027. Epub 2012 Oct 11.

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