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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Constitutive and xenobiotics-induced expression of a novel CYP3A gene from zebrafish larva

Authors:
Tseng HP, Hseu TH, Buhler DR, Wang WD, Hu CH
Citation:
Toxicol Appl Pharmacol. 2005 Jun 15;205(3):247-58. Epub 2004 Dec 28
Epub:
Not Epub
Abstract:
In mammals, CYP3A isozymes collectively comprise the largest portion of the liver and small intestinal CYP protein. They are...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tseng HP, Hseu TH, Buhler DR, Wang WD, Hu CH. Constitutive and xenobiotics-induced expression of a novel CYP3A gene from zebrafish larva. Toxicol Appl Pharmacol. 2005 Jun 15;205(3):247-58. Epub 2004 Dec 28.

Contribution of mGluR and Fmr1 Functional Pathways to Neurite Morphogenesis, Craniofacial Development and Fragile X Syndrome

Authors:
Tucker B, Richards RI, Lardelli M
Citation:
Hum Mol Genet. 2006 Dec 1;15(23):3446-58. Epub 2006 Oct 25.
Epub:
Not Epub
Abstract:
Fragile X Syndrome is a leading heritable cause of mental retardation that results from the loss of FMR1 gene function. Studies...
Organism or Cell Type:
zebrafish
Citation Extract:
Tucker B, Richards RI, Lardelli M. Contribution of mGluR and Fmr1 Functional Pathways to Neurite Morphogenesis, Craniofacial Development and Fragile X Syndrome. Hum Mol Genet. 2006 Dec 1;15(23):3446-58. Epub 2006 Oct 25..

Controlling gene loss of function in newts with emphasis on lens regeneration

Authors:
Tsonis PA, Haynes T, Maki N, Nakamura K, Casco-Robles MM, Yamada S, Miura T, Chiba C, Del Rio-Tsonis K
Citation:
Nature Protocols. 2011;6:593–599 doi:10.1038/nprot.2011.341
Epub:
Not Epub
Abstract:
Here we describe a protocol for gene loss of function during regeneration in newts, specifically applied to lens regeneration....
Delivery Method:
Vivo-Morpholino in vivo, Morpholinos and Endo-Porter in cultures
Organism or Cell Type:
Notophthalmus viridescens (newt), cell cutlures and in vivo
Citation Extract:
Tsonis PA, Haynes T, Maki N, Nakamura K, Casco-Robles MM, Yamada S, Miura T, Chiba C, Del Rio-Tsonis K. Controlling gene loss of function in newts with emphasis on lens regeneration. Nature Protocols. 2011;6:593–599 doi:10.1038/nprot.2011.341.

Deficiency of ribosomal protein S19 during early embryogenesis leads to reduction of erythrocytes in a zebrafish model of Diamond-Blackfan anemia

Authors:
Uechi T, Nakajima Y, Chakraborty A, Torihara H, Higa S, Kenmochi N
Citation:
Hum Mol Genet. 2008 Jul 24. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Ribosomes are responsible for protein synthesis in all cells. Ribosomal protein S19 (RPS19) is one of the 79 ribosomal proteins...
Organism or Cell Type:
zebrafish
Citation Extract:
Uechi T, Nakajima Y, Chakraborty A, Torihara H, Higa S, Kenmochi N. Deficiency of ribosomal protein S19 during early embryogenesis leads to reduction of erythrocytes in a zebrafish model of Diamond-Blackfan anemia. Hum Mol Genet. 2008 Jul 24. [Epub ahead of print].

Design and use of transgenic reporter strains for detecting activity of signaling pathways in Xenopus

Authors:
Tran HT, Vleminckx K
Citation:
Methods. 2013 Jun 28. doi:pii: S1046-2023(13)00240-5. 10.1016/j.ymeth.2013.06.028. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Embryos and larvae of vertebrate species with external development are ideal subjects for investigating the dynamic...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Tran HT, Vleminckx K. Design and use of transgenic reporter strains for detecting activity of signaling pathways in Xenopus. Methods. 2013 Jun 28. doi:pii: S1046-2023(13)00240-5. 10.1016/j.ymeth.2013.06.028. [Epub ahead of print].

Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning

Authors:
Umasankar PK, Sanker S, Thieman JR, Chakraborty S, Wendland B, Tsang M, Traub LM
Citation:
Nat Cell Biol. 2012 Apr 8. doi: 10.1038/ncb2473. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Clathrin-mediated endocytosis occurs at multiple independent import sites on the plasma membrane, but how these positions are...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Umasankar PK, Sanker S, Thieman JR, Chakraborty S, Wendland B, Tsang M, Traub LM. Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning. Nat Cell Biol. 2012 Apr 8. doi: 10.1038/ncb2473. [Epub ahead of print].

doublesex/mab3 related-1 (dmrt1) is essential for development of anterior neural plate derivatives in Ciona

Authors:
Tresser J, Chiba S, Veeman M, El-Nachef D, Newman-Smith E, Horie T, Tsuda M, Smith WC
Citation:
Development. 2010 Jul;137(13):2197-203
Epub:
Not Epub
Abstract:
Ascidian larvae have a hollow, dorsal central nervous system that shares many morphological features with vertebrate nervous...
Delivery Method:
Microinjection
Organism or Cell Type:
Ciona savignyi
Citation Extract:
Tresser J, Chiba S, Veeman M, El-Nachef D, Newman-Smith E, Horie T, Tsuda M, Smith WC. doublesex/mab3 related-1 (dmrt1) is essential for development of anterior neural plate derivatives in Ciona. Development. 2010 Jul;137(13):2197-203.

Down-regulation of ATM protein sensitizes human prostate cancer cells to radiation-induced apoptosis

Authors:
Truman JP, Gueven N, Lavin M, Leibel S, Kolesnick R, Fuks Z, Haimovitz-Friedman A
Citation:
J Biol Chem. 2005 Jun 17;280(24):23262-72. Epub 2005 Apr 18
Epub:
Not Epub
Abstract:
Treatment with the protein kinase C activator 12-O-tetradecanoylphorbol 12-acetate (TPA) enables radiation-resistant LNCaP...
Delivery Method:
Scrape Delivery
Organism or Cell Type:
Cell culture: Human prostate cancer LNCaP, PC-3, DU 145 and CWR22-Rv1
Citation Extract:
Truman JP, Gueven N, Lavin M, Leibel S, Kolesnick R, Fuks Z, Haimovitz-Friedman A. Down-regulation of ATM protein sensitizes human prostate cancer cells to radiation-induced apoptosis. J Biol Chem. 2005 Jun 17;280(24):23262-72. Epub 2005 Apr 18.

Dual suppression of hemangiogenesis and lymphangiogenesis by splice-shifting morpholinos targeting vascular endothelial growth factor receptor 2 (KDR)

Authors:
Uehara H, Cho Y, Simonis J, Cahoon J, Archer B, Luo L, Das SK, Singh N, Ambati J, Ambati BK
Citation:
FASEB J, 2013 Jan; 27(1):76–85. doi:10.1096/fj.12-213835
Epub:
Not Epub
Abstract:
The KDR gene, which participates in angiogenesis and lymphangiogenesis, produces two functionally distinct protein products,...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528308/
Delivery Method:
in vitro nucleifection; in vivo intravitreal or subconjunctival Vivo-Morpholino injection
Organism or Cell Type:
cell culture, mouse cornea
Citation Extract:
Uehara H, Cho Y, Simonis J, Cahoon J, Archer B, Luo L, Das SK, Singh N, Ambati J, Ambati BK. Dual suppression of hemangiogenesis and lymphangiogenesis by splice-shifting morpholinos targeting vascular endothelial growth factor receptor 2 (KDR). FASEB J, 2013 Jan; 27(1):76–85. doi:10.1096/fj.12-213835 .

Effects of Stanniocalcin 1 on calcium uptake in zebrafish (Danio rerio) embryo

Authors:
Tseng DY, Chou MY, Tseng YC, Hsiao CD, Huang CJ, Kaneko T, Hwang PP
Citation:
Am J Physiol Regul Integr Comp Physiol. 2008 Dec 10. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Stanniocalcin (STC, formerly called hypocalcin or teleocalcin) is a 50-kDa disulfide-linked homodimeric glycoprotein that was...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tseng DY, Chou MY, Tseng YC, Hsiao CD, Huang CJ, Kaneko T, Hwang PP. Effects of Stanniocalcin 1 on calcium uptake in zebrafish (Danio rerio) embryo. Am J Physiol Regul Integr Comp Physiol. 2008 Dec 10. [Epub ahead of print] .

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