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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Identification of an INSM1 Binding Site in the Insulin Promoter: Negative Regulation of the Insulin Gene Transcription

Authors:
Wang HW, Muguira M, Liu WD, Zhang T, Chen C, Aucoin R, Breslin M, Lan M
Citation:
J Endocrinol. 2008 Jul;198(1):29-39. Epub 2008 Apr 16.
Epub:
Not Epub
Abstract:
In this study, an INSM1-binding site in the proximal promoter sequence of the insulin gene was identified. Co-transfection of...
Organism or Cell Type:
Mouse embryonic pancreas
Citation Extract:
Wang HW, Muguira M, Liu WD, Zhang T, Chen C, Aucoin R, Breslin M, Lan M. Identification of an INSM1 Binding Site in the Insulin Promoter: Negative Regulation of the Insulin Gene Transcription. J Endocrinol. 2008 Jul;198(1):29-39. Epub 2008 Apr 16..

Identification of Small Molecule Activators of BMP Signaling

Authors:
Vrijens K, Lin W, Cui J, Farmer D, Low J, Pronier E, Zeng F-Y, Shelat AA, Guy K, Taylor MR, Chen T, Roussei MF
Citation:
PLoS ONE. 2013;8(3):e59045. doi:10.1371/journal.pone.0059045
Epub:
Not Epub
Abstract:
Bone Morphogenetic Proteins (BMPs) are morphogens that play a major role in regulating development and homeostasis. Although...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Vrijens K, Lin W, Cui J, Farmer D, Low J, Pronier E, Zeng F-Y, Shelat AA, Guy K, Taylor MR, Chen T, Roussei MF. Identification of Small Molecule Activators of BMP Signaling. PLoS ONE. 2013;8(3):e59045. doi:10.1371/journal.pone.0059045.

In vitro evaluation of novel antisense oligonucleotides is predictive of in vivo exon skipping activity for Duchenne muscular dystrophy

Authors:
Wang Q, Yin H, Camelliti P, Betts C, Moulton H, Lee H, Saleh AF, Gait MJ, Wood MJ
Citation:
J Gene Med. 2010 Mar 16. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Targeted splice modulation of pre-mRNA transcripts by antisense oligonucleotides (AOs) can correct the function of...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mdk mice, H2K mdx cells
Citation Extract:
Wang Q, Yin H, Camelliti P, Betts C, Moulton H, Lee H, Saleh AF, Gait MJ, Wood MJ. In vitro evaluation of novel antisense oligonucleotides is predictive of in vivo exon skipping activity for Duchenne muscular dystrophy. J Gene Med. 2010 Mar 16. [Epub ahead of print].

Induction of Antagonistic Soluble Decoy Receptor Tyrosine Kinases by Intronic PolyA Activation

Authors:
Vorlová S, Rocco G, LeFave CV, Jodelka FM, Hess K, Hastings ML, Henke H, Cartegni L
Citation:
Mol Cell. 2011;(43)6:927-39
Epub:
Not Epub
Abstract:
Alternative intronic polyadenylation (IPA) can generate truncated protein isoforms with significantly altered functions. Here,...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: HeLa, MDA-231 & HUVEC
Citation Extract:
Vorlová S, Rocco G, LeFave CV, Jodelka FM, Hess K, Hastings ML, Henke H, Cartegni L. Induction of Antagonistic Soluble Decoy Receptor Tyrosine Kinases by Intronic PolyA Activation. Mol Cell. 2011;(43)6:927-39.

Initiation and propagation of posterior to anterior (PA) waves in zebrafish left-right development

Authors:
Wang X, Yost HJ
Citation:
Dev Dyn. 2008 Nov 4. [Epub ahead of print]
Epub:
Not Epub
Abstract:
One of the most highly conserved steps in left-right patterning is asymmetric gene expression in lateral plate mesoderm (LPM)....
Organism or Cell Type:
zebrafish
Citation Extract:
Wang X, Yost HJ. Initiation and propagation of posterior to anterior (PA) waves in zebrafish left-right development. Dev Dyn. 2008 Nov 4. [Epub ahead of print].

Knockdown of FABP3 Impairs Cardiac Development in Zebrafish through the Retinoic Acid Signaling Pathway

Authors:
Wang X, Zhou L, Jin J, Yang Y, Song G, Shen Y, Liu H, Liu M, Shi C, Qian L
Citation:
Int J Mol Sci. 2013;14(7):13826-41. doi:10.3390/ijms140713826 (doi registration under processing)
Epub:
Not Epub
Abstract:
Fatty acid-binding protein 3 (FABP3) is a member of the intracellular lipid-binding protein family, and is primarily expressed...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang X, Zhou L, Jin J, Yang Y, Song G, Shen Y, Liu H, Liu M, Shi C, Qian L. Knockdown of FABP3 Impairs Cardiac Development in Zebrafish through the Retinoic Acid Signaling Pathway. Int J Mol Sci. 2013;14(7):13826-41. doi:10.3390/ijms140713826 (doi registration under processing).

Label-Free DNA Sensor Based on Surface Charge Modulated Ionic Conductance

Authors:
Wang X, Smirnov S
Citation:
ACS Nano. 2009 Mar 13. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The surface charge effect in controlling ionic conductance through a nanoporous alumina membrane is investigated for its...
Citation Extract:
Wang X, Smirnov S. Label-Free DNA Sensor Based on Surface Charge Modulated Ionic Conductance. ACS Nano. 2009 Mar 13. [Epub ahead of print].

LAR receptor tyrosine phosphatases and HSPGs guide peripheral sensory axons to the skin

Authors:
Wang F, Wolfson SN, Gharib A, Sagasti A
Citation:
Curr Biol. 2012 Mar 6;22(5):373-82. doi: 10.1016/j.cub.2012.01.040. Epub 2012 Feb 9
Epub:
Not Epub
Abstract:
BACKGROUND: Peripheral axons of somatosensory neurons innervate the skin early in development to detect touch stimuli....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang F, Wolfson SN, Gharib A, Sagasti A. LAR receptor tyrosine phosphatases and HSPGs guide peripheral sensory axons to the skin. Curr Biol. 2012 Mar 6;22(5):373-82. doi: 10.1016/j.cub.2012.01.040. Epub 2012 Feb 9.

Live imaging of neutrophil motility in a zebrafish model of WHIM syndrome

Authors:
Walters KB, Green JM, Surfus JC, Yoo SK, Huttenlocher A
Citation:
Blood. 2010 Jun 30. [Epub ahead of print]
Epub:
Not Epub
Abstract:
CXCR4 is a G-protein coupled chemokine receptor that has been implicated in the pathogenesis of primary immunodeficiency...
Organism or Cell Type:
zebrafish
Citation Extract:
Walters KB, Green JM, Surfus JC, Yoo SK, Huttenlocher A. Live imaging of neutrophil motility in a zebrafish model of WHIM syndrome. Blood. 2010 Jun 30. [Epub ahead of print].

Mef2c is an essential regulatory element required for unique expression of the cardiac-specific CARK gene

Authors:
Wang H, Chen C, Song X, Chen J, Zhen Y, Sun K, Hui R
Citation:
J Cell Mol Med. 2008 Jan-Feb;12(1):304-15. Epub 2007 Nov 16.
Epub:
Not Epub
Abstract:
The cardiac ankyrin repeat kinase (CARK) gene, also named TNNI3K for its interaction with cardiac troponin I, is a both unique...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: rat cardiac myocytes
Citation Extract:
Wang H, Chen C, Song X, Chen J, Zhen Y, Sun K, Hui R. Mef2c is an essential regulatory element required for unique expression of the cardiac-specific CARK gene. J Cell Mol Med. 2008 Jan-Feb;12(1):304-15. Epub 2007 Nov 16..

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