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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Analysis of Gene Function and Visualization of Cilia-Generated Fluid Flow in Kupffer's Vesicle

Authors:
Wang G, Yost HJ, Amack JD
Citation:
J Vis Exp. 2013 Mar 31;(73). doi: 10.3791/50038
Epub:
Not Epub
Abstract:
Internal organs such as the heart, brain, and gut develop left-right (LR) asymmetries that are critical for their normal...
Delivery Method:
stage-specific injections
Organism or Cell Type:
zebrafish
Citation Extract:
Wang G, Yost HJ, Amack JD. Analysis of Gene Function and Visualization of Cilia-Generated Fluid Flow in Kupffer's Vesicle. J Vis Exp. 2013 Mar 31;(73). doi: 10.3791/50038.

Antisense morpholino targeting just upstream from a poly(A) tail junction of maternal mRNA removes the tail and inhibits translation

Authors:
Wada T, Hara M, Taneda T, Qingfu C, Takata R, Moro K, Takeda K, Kishimoto T, Handa H
Citation:
Nucleic Acids Res. 2012 Dec;40(22):e173. doi: 10.1093/nar/gks765. Epub 2012 Aug 16.
Epub:
Not Epub
Abstract:
Gene downregulation by antisense morpholino oligonucleotides (MOs) is achieved by either hybridization around the translation...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish and starfish
Citation Extract:
Wada T, Hara M, Taneda T, Qingfu C, Takata R, Moro K, Takeda K, Kishimoto T, Handa H. Antisense morpholino targeting just upstream from a poly(A) tail junction of maternal mRNA removes the tail and inhibits translation. Nucleic Acids Res. 2012 Dec;40(22):e173. doi: 10.1093/nar/gks765. Epub 2012 Aug 16..

APOBEC2, a selective inhibitor of TGFβ signaling, regulates left-right axis specification during early embryogenesis

Authors:
Vonica A, Rosa A, Arduini BL, Brivanlou AH
Citation:
Dev Biol. 2011 Feb 1;350(1):13-23. Epub 2010 Sep 27
Epub:
Not Epub
Abstract:
The specification of left-right asymmetry is an evolutionarily conserved developmental process in vertebrates. The interplay...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Vonica A, Rosa A, Arduini BL, Brivanlou AH. APOBEC2, a selective inhibitor of TGFβ signaling, regulates left-right axis specification during early embryogenesis. Dev Biol. 2011 Feb 1;350(1):13-23. Epub 2010 Sep 27.

Ascidian otx gene Hroth activates transcription of the brain-specific gene HrTRP

Authors:
Wada S, Toyoda R, Yamamoto H, Saiga H
Citation:
Dev Dyn 2002 Sep;225(1):46-53
Epub:
Not Epub
Abstract:
The brain (sensory vesicle) of the ascidian larvae is thought to be homologous to the vertebrate forebrain and midbrain and,...
Delivery Method:
Microinjection
Organism or Cell Type:
Halocynthia roretzi (ascidian)
Citation Extract:
Wada S, Toyoda R, Yamamoto H, Saiga H. Ascidian otx gene Hroth activates transcription of the brain-specific gene HrTRP. Dev Dyn 2002 Sep;225(1):46-53.

ATP4a Is Required for Wnt-Dependent Foxj1 Expression and Leftward Flow in Xenopus Left-Right Development

Authors:
Walentek P, Beyer T, Thumberger T, Schweickert A, Blum M
Citation:
Cell Reports. 2012;[Epub ahead of print] doi:10.1016/j.celrep.2012.03.005
Epub:
Not Epub
Abstract:
Most vertebrate embryos break symmetry by a cilia-driven leftward flow during neurulation. In the frog Xenopus asymmetric...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Walentek P, Beyer T, Thumberger T, Schweickert A, Blum M. ATP4a Is Required for Wnt-Dependent Foxj1 Expression and Leftward Flow in Xenopus Left-Right Development. Cell Reports. 2012;[Epub ahead of print] doi:10.1016/j.celrep.2012.03.005.

C terminus of RGS-GAIP-interacting protein conveys neuropilin-1-mediated signaling during angiogenesis

Authors:
Wang L, Mukhopadhyay D, Xu X
Citation:
FASEB J. 2006 Jul;20(9):1513-5. Epub 2006 Jun 5
Epub:
Not Epub
Abstract:
Initially, it was thought that there was no intracellular signaling mediated by NRP-1 alone in response to its ligands. However...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang L, Mukhopadhyay D, Xu X. C terminus of RGS-GAIP-interacting protein conveys neuropilin-1-mediated signaling during angiogenesis. FASEB J. 2006 Jul;20(9):1513-5. Epub 2006 Jun 5.

Casein Kinase 1 Alpha Regulates Chromosome Congression and Separation during Mouse Oocyte Meiotic Maturation and Early Embryo Development

Authors:
Wang L, Lu A, Zhou H-X, Sun R, Zhao J, Zhou C-J, Shen J-P, Wu S-N, Liang C-G
Citation:
PLoS ONE. 2013;8(5):e63173. doi:10.1371/journal.pone.0063173
Epub:
Not Epub
Abstract:
Casein kinase I alpha (CK1α) is a member of serine/threonine protein kinase, generally present in all eukaryotes. In mammals,...
Delivery Method:
Microinjection
Organism or Cell Type:
mouse oocytes
Citation Extract:
Wang L, Lu A, Zhou H-X, Sun R, Zhao J, Zhou C-J, Shen J-P, Wu S-N, Liang C-G. Casein Kinase 1 Alpha Regulates Chromosome Congression and Separation during Mouse Oocyte Meiotic Maturation and Early Embryo Development. PLoS ONE. 2013;8(5):e63173. doi:10.1371/journal.pone.0063173.

Cellular Retinol Binding Protein 1 Modulates Photoreceptor Outer Segment Folding In the Isolated Eye

Authors:
Wang X, Tong Y, Giorgianni F, Beranova-Giorgianni S, Penn JS, Jablonski MM
Citation:
Dev Neurobiol. 2010 Apr 13. [Epub ahead of print]
Epub:
Not Epub
Abstract:
In a previous study, we used differential proteomics to identify retinal proteins whose steady-state levels were altered in an...
Citation Extract:
Wang X, Tong Y, Giorgianni F, Beranova-Giorgianni S, Penn JS, Jablonski MM. Cellular Retinol Binding Protein 1 Modulates Photoreceptor Outer Segment Folding In the Isolated Eye. Dev Neurobiol. 2010 Apr 13. [Epub ahead of print].

Corticotropin-releasing factor critical for zebrafish camouflage behavior is regulated by light and sensitive to ethanol

Authors:
Wagle M, Mathur P, Guo S
Citation:
J Neurosci. 2011 Jan 5;31(1):214-24
Epub:
Not Epub
Abstract:
The zebrafish camouflage response is an innate “hard-wired” behavior that offers an excellent opportunity to explore neural...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wagle M, Mathur P, Guo S. Corticotropin-releasing factor critical for zebrafish camouflage behavior is regulated by light and sensitive to ethanol. J Neurosci. 2011 Jan 5;31(1):214-24.

Cranioectodermal Dysplasia, Sensenbrenner syndrome, is a ciliopathy caused by mutations in the IFT122 gene

Authors:
Walczak-Sztulpa J, Eggenschwiler J, Osborn D, Brown DA, Emma F, Klingenberg C, Hennekam RC, Torre G, Garshasbi M, Tzschach A, Szczepanska M, Krawczynski M, Zachwieja J, Zwolinska D, Beales PL, Ropers HH, Latos-Bielenska A, Kuss AW
Citation:
Am J Hum Genet. 2010 Jun 11;86(6):949-56. Epub 2010 May 20
Epub:
Not Epub
Abstract:
Cranioectodermal dysplasia (CED) is a disorder characterized by craniofacial, skeletal, and ectodermal abnormalities. Most...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Walczak-Sztulpa J, Eggenschwiler J, Osborn D, Brown DA, Emma F, Klingenberg C, Hennekam RC, Torre G, Garshasbi M, Tzschach A, Szczepanska M, Krawczynski M, Zachwieja J, Zwolinska D, Beales PL, Ropers HH, Latos-Bielenska A, Kuss AW. Cranioectodermal Dysplasia, Sensenbrenner syndrome, is a ciliopathy caused by mutations in the IFT122 gene. Am J Hum Genet. 2010 Jun 11;86(6):949-56. Epub 2010 May 20.

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