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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Loss of zygotic NUP107 protein causes missing of pharyngeal skeleton and other tissue defects with impaired nuclear pore function in zebrafish embryos

Authors:
Zheng X, Yang S, Han Y, Zhao X, Zhao L, Tian T, Tong J, Xu P, Xiong C, Meng A
Citation:
J Biol Chem. 2012 Sep 10. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The Nup107-160 multiprotein subcomplex is essential for the assembly of nuclear pore complexes. The developmental functions of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zheng X, Yang S, Han Y, Zhao X, Zhao L, Tian T, Tong J, Xu P, Xiong C, Meng A. Loss of zygotic NUP107 protein causes missing of pharyngeal skeleton and other tissue defects with impaired nuclear pore function in zebrafish embryos. J Biol Chem. 2012 Sep 10. [Epub ahead of print].

Lrig3 regulates neural crest formation in Xenopus by modulating Fgf and Wnt signaling pathways

Authors:
Zhao H, Tanegashima K, Ro H, Dawid IB
Citation:
Development. 2008 Feb 20; [Epub ahead of print]
Epub:
Not Epub
Abstract:
Leucine-rich repeats and immunoglobulin-like domains 3 (Lrig3) was identified by microarray analysis among genes that show...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Zhao H, Tanegashima K, Ro H, Dawid IB. Lrig3 regulates neural crest formation in Xenopus by modulating Fgf and Wnt signaling pathways. Development. 2008 Feb 20; [Epub ahead of print].

Macrophage-specific gene functions in Spi1-directed innate immunity

Authors:
Zakrzewska A, Cui C, Stockhammer OW, Benard EL, Spaink HP, Meijer AH
Citation:
Blood. 2010 Apr 27. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The Spi1/Pu.1 transcription factor plays a crucial role in myeloid cell development in vertebrates. Despite extensive studies...
Organism or Cell Type:
zebrafish
Citation Extract:
Zakrzewska A, Cui C, Stockhammer OW, Benard EL, Spaink HP, Meijer AH. Macrophage-specific gene functions in Spi1-directed innate immunity. Blood. 2010 Apr 27. [Epub ahead of print].

MAPK-activated protein kinase 2 is required for mouse meiotic spindle assembly and kinetochore-microtubule attachment

Authors:
Yuan J, Xu BZ, Qi ST, Tong JS, Wei L, Li M, Ouyang YC, Hou Y, Schatten H, Sun QY
Citation:
PLoS One. 2010 Jun 28;5(6):e11247
Epub:
Not Epub
Abstract:
MAPK-activated protein kinase 2 (MK2), a direct substrate of p38 MAPK, plays key roles in multiple physiological functions in...
Delivery Method:
Microinjection
Organism or Cell Type:
mouse oocytes
Citation Extract:
Yuan J, Xu BZ, Qi ST, Tong JS, Wei L, Li M, Ouyang YC, Hou Y, Schatten H, Sun QY. MAPK-activated protein kinase 2 is required for mouse meiotic spindle assembly and kinetochore-microtubule attachment. PLoS One. 2010 Jun 28;5(6):e11247.

Massively parallel sequencing identifies the gene Megf8 with ENU-induced mutation causing heterotaxy

Authors:
Zhang Z, Alpert D, Francis R, Chatterjee B, Yu Q, Tansey T, Sabol SL, Cui C, Bai Y, Koriabine M, Yoshinaga Y, Cheng JF, Chen F, Martin J, Schackwitz W, Gunn TM, Kramer KL, De Jong PJ, Pennacchio LA, Lo CW
Citation:
Proc Natl Acad Sci U S A. 2009 Feb 13. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Forward genetic screens with ENU (N-ethyl-N-nitrosourea) mutagenesis can facilitate gene discovery, but mutation identification...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Z, Alpert D, Francis R, Chatterjee B, Yu Q, Tansey T, Sabol SL, Cui C, Bai Y, Koriabine M, Yoshinaga Y, Cheng JF, Chen F, Martin J, Schackwitz W, Gunn TM, Kramer KL, De Jong PJ, Pennacchio LA, Lo CW. Massively parallel sequencing identifies the gene Megf8 with ENU-induced mutation causing heterotaxy. Proc Natl Acad Sci U S A. 2009 Feb 13. [Epub ahead of print].

Microinjection of mRNA and morpholino antisense oligonucleotides in zebrafish embryos

Authors:
Yuan S, Sun Z
Citation:
J Vis Exp. 2009 May 7;(27). pii: 1113. doi: 10.3791/1113
Epub:
Not Epub
Abstract:
An essential tool for investigating the role of a gene during development is the ability to perform gene knockdown,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yuan S, Sun Z. Microinjection of mRNA and morpholino antisense oligonucleotides in zebrafish embryos. J Vis Exp. 2009 May 7;(27). pii: 1113. doi: 10.3791/1113.

MicroRNA miR-133b is essential for functional recovery after spinal cord injury in adult zebrafish

Authors:
Yu YM, Gibbs KM, Davila J, Campbell N, Sung S, Todorova TI, Otsuka S, Sabaawy HE, Hart RP, Schachner M
Citation:
Eur J Neurosci. 2011 May;33(9):1587-97. doi: 10.1111/j.1460-9568.2011.07643.x. Epub 2011 Mar 30.
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) play important roles during development and also in adult organisms by regulating the expression of multiple...
Delivery Method:
Gelfoam at lesion
Organism or Cell Type:
zebrafish
Citation Extract:
Yu YM, Gibbs KM, Davila J, Campbell N, Sung S, Todorova TI, Otsuka S, Sabaawy HE, Hart RP, Schachner M. MicroRNA miR-133b is essential for functional recovery after spinal cord injury in adult zebrafish. Eur J Neurosci. 2011 May;33(9):1587-97. doi: 10.1111/j.1460-9568.2011.07643.x. Epub 2011 Mar 30..

MicroRNA-Mediated Control of Oligodendrocyte Differentiation

Authors:
Zhao X, He X, Han X, Yu Y, Ye F, Chen Y, Hoang T, Xu X, Mi QS, Xin M, Wang F, Appel B, Lu QR
Citation:
Neuron. 2010 Mar 11;65(5):612-626
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) regulate various biological processes, but evidence for miRNAs that control the differentiation program of...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao X, He X, Han X, Yu Y, Ye F, Chen Y, Hoang T, Xu X, Mi QS, Xin M, Wang F, Appel B, Lu QR. MicroRNA-Mediated Control of Oligodendrocyte Differentiation. Neuron. 2010 Mar 11;65(5):612-626.

miR-145 directs intestinal maturation in zebrafish

Authors:
Zeng L, Carter AD, Childs SJ
Citation:
Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17793-8. Epub 2009 Oct 5
Epub:
Not Epub
Abstract:
The rapid specification and differentiation of the embryonic zebrafish gut is essential to provide contractility for the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zeng L, Carter AD, Childs SJ. miR-145 directs intestinal maturation in zebrafish. Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17793-8. Epub 2009 Oct 5.

Morpholino-functionalized silicon nanowire biosensor for sequence-specific label-free detection of DNA

Authors:
Zhang GJ, Luo ZH, Huang MJ, Tay GK, Lim EJ
Citation:
Biosens Bioelectron. 2010 Apr 9. [Epub ahead of print]
Epub:
Not Epub
Abstract:
We investigated Morpholino-functionalized silicon nanowires (SiNWs) as a novel gene chip platform for the sequence-specific...
Citation Extract:
Zhang GJ, Luo ZH, Huang MJ, Tay GK, Lim EJ. Morpholino-functionalized silicon nanowire biosensor for sequence-specific label-free detection of DNA. Biosens Bioelectron. 2010 Apr 9. [Epub ahead of print].

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