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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Activation of Smurf E3 Ligase Promoted by Smoothened Regulates Hedgehog Signaling through Targeting Patched Turnover

Authors:
Huang S, Zhang Z, Zhang C, Lv X, Zheng X, Chen Z, Wang H, Zhu Y, Zhang J, Yang S, Sun Q, Tao Y, Liu F, Zhao Y, Chen D
Citation:
PLoS Biol. 2013;11(11):e1001721. doi:10.1371/journal.pbio.1001721
Epub:
Not Epub
Abstract:
Hedgehog signaling plays conserved roles in controlling embryonic development; its dysregulation has been implicated in many...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Huang S, Zhang Z, Zhang C, Lv X, Zheng X, Chen Z, Wang H, Zhu Y, Zhang J, Yang S, Sun Q, Tao Y, Liu F, Zhao Y, Chen D. Activation of Smurf E3 Ligase Promoted by Smoothened Regulates Hedgehog Signaling through Targeting Patched Turnover. PLoS Biol. 2013;11(11):e1001721. doi:10.1371/journal.pbio.1001721.

Oxidative Stress and Regulation of Pink1 in Zebrafish (Danio rerio)

Authors:
Priyadarshini M, Orosco LA, Panula PJ
Citation:
PLoS ONE. 2013;8(11):e81851. doi:10.1371/journal.pone.0081851
Epub:
Not Epub
Abstract:
Oxidative stress-mediated neuronal dysfunction is characteristic of several neurodegenerative disorders, including Parkinson’s...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Priyadarshini M, Orosco LA, Panula PJ. Oxidative Stress and Regulation of Pink1 in Zebrafish (Danio rerio). PLoS ONE. 2013;8(11):e81851. doi:10.1371/journal.pone.0081851.

Wdpcp, a PCP Protein Required for Ciliogenesis, Regulates Directional Cell Migration and Cell Polarity by Direct Modulation of the Actin Cytoskeleton

Authors:
Cui C, Chatterjee B, Lozito TP, Zhang Z, Francis RJ, Yagi H, Swanhart LM, Sanker S, Francis D, Yu Q, San Agustin JT, Puligilla C, Chatterjee T, Tansey T, Lou X, Kelley MW, Spiliotis ET, Kwiatkowski AV, Tuan R, Pazour GJ, Hukriede NA, Lo CW
Citation:
PLoS Biol. 2013;11(11):e1001720. doi:10.1371/journal.pbio.1001720
Epub:
Not Epub
Abstract:
Planar cell polarity (PCP) regulates cell alignment required for collective cell movement during embryonic development. This...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cui C, Chatterjee B, Lozito TP, Zhang Z, Francis RJ, Yagi H, Swanhart LM, Sanker S, Francis D, Yu Q, San Agustin JT, Puligilla C, Chatterjee T, Tansey T, Lou X, Kelley MW, Spiliotis ET, Kwiatkowski AV, Tuan R, Pazour GJ, Hukriede NA, Lo CW. Wdpcp, a PCP Protein Required for Ciliogenesis, Regulates Directional Cell Migration and Cell Polarity by Direct Modulation of the Actin Cytoskeleton. PLoS Biol. 2013;11(11):e1001720. doi:10.1371/journal.pbio.1001720.

Matrilin-1 is Essential for Zebrafish Development by Facilitating Collagen II Secretion

Authors:
Neacsu CD, Ko Y-P, Tagariello A, Karlsen KR, Neiss WF, Paulsson M, Wagener R
Citation:
J Biol Chem. 2013;[Epub ahead of print] doi:10.1074/jbc.M113.529933
Epub:
Yes
Abstract:
Matrilin-1 is the prototypical member of the matrilin protein family and is highly expressed in cartilage. However, gene...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Neacsu CD, Ko Y-P, Tagariello A, Karlsen KR, Neiss WF, Paulsson M, Wagener R. Matrilin-1 is Essential for Zebrafish Development by Facilitating Collagen II Secretion. J Biol Chem. 2013;[Epub ahead of print] doi:10.1074/jbc.M113.529933 .

Novel evolutionary-conserved role for the activity-dependent neuroprotective protein (ADNP) family that is important for erythropoiesis

Authors:
Dresner E, Malishkevich A, Arviv C, Leibman Barak S, Alon S, Ofir R, Gothilf Y, Gozes I
Citation:
J Biol Chem. 2012 Nov 23;287(48):40173-85. doi: 10.1074/jbc.M112.387027. Epub 2012 Oct 15
Epub:
Not Epub
Abstract:
BACKGROUND: ADNP is vital for embryonic development. Is this function conserved for the homologous protein ADNP2? RESULTS:...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dresner E, Malishkevich A, Arviv C, Leibman Barak S, Alon S, Ofir R, Gothilf Y, Gozes I. Novel evolutionary-conserved role for the activity-dependent neuroprotective protein (ADNP) family that is important for erythropoiesis. J Biol Chem. 2012 Nov 23;287(48):40173-85. doi: 10.1074/jbc.M112.387027. Epub 2012 Oct 15.

Aggf1 acts at the top of the genetic regulatory hierarchy in specification of hemangioblasts in zebrafish

Authors:
Li L, Chen D, Li J, Wang X, Wang N, Xu C, Wang QK
Citation:
Blood. 2013 Nov 25. [Epub ahead of print]
Epub:
Yes
Abstract:
The hemangioblast is a multipotential progenitor, which is derived from the mesoderm and can further differentiate into...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li L, Chen D, Li J, Wang X, Wang N, Xu C, Wang QK. Aggf1 acts at the top of the genetic regulatory hierarchy in specification of hemangioblasts in zebrafish. Blood. 2013 Nov 25. [Epub ahead of print].

Chordin forms a self-organizing morphogen gradient in the extracellular space between ectoderm and mesoderm in the Xenopus embryo

Authors:
Plouhinec JL, Zakin L, Moriyama Y, De Robertis EM
Citation:
Proc Natl Acad Sci U S A. 2013 Nov 27. [Epub ahead of print]
Epub:
Yes
Abstract:
The vertebrate body plan follows stereotypical dorsal-ventral (D-V) tissue differentiation controlled by bone morphogenetic...
Organism or Cell Type:
Xenopus
Citation Extract:
Plouhinec JL, Zakin L, Moriyama Y, De Robertis EM. Chordin forms a self-organizing morphogen gradient in the extracellular space between ectoderm and mesoderm in the Xenopus embryo. Proc Natl Acad Sci U S A. 2013 Nov 27. [Epub ahead of print].

Glutaredoxin regulates vascular development by reversible glutathionylation of sirtuin 1

Authors:
Bräutigam L, Jensen LDE, Poschmann G, Nyström S, Bannenberg S, Dreij K, Lepka K, Prozorovski T, Montano SJ, Aktas O, Uhlén P, Stühler K, Cao Y, Holmgren A, Berndt C
Citation:
PNAS. 2013;[Epub ahead of print] doi:10.1073/pnas.1313753110
Epub:
Not Epub
Abstract:
Embryonic development depends on complex and precisely orchestrated signaling pathways including specific reduction/oxidation...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bräutigam L, Jensen LDE, Poschmann G, Nyström S, Bannenberg S, Dreij K, Lepka K, Prozorovski T, Montano SJ, Aktas O, Uhlén P, Stühler K, Cao Y, Holmgren A, Berndt C. Glutaredoxin regulates vascular development by reversible glutathionylation of sirtuin 1. PNAS. 2013;[Epub ahead of print] doi:10.1073/pnas.1313753110.

Dystromirs as Serum Biomarkers for Monitoring the Disease Severity in Duchenne Muscular Dystrophy

Authors:
Zaharieva IT, Calissano M, Scoto M, Preston M, Cirak S, Feng L, Collins J, Kole R, Guglieri M, Straub V, Bushby K, Ferlini A, Morgan JE, Muntoni F
Citation:
PLoS ONE. 2013;8(11):e80263. doi:10.1371/journal.pone.0080263
Epub:
Not Epub
Abstract:
Duchenne muscular Dystrophy (DMD) is an inherited disease caused by mutations in the dystrophin gene that disrupt the open...
Delivery Method:
i.v. infusion
Organism or Cell Type:
Human - clinical trials
Citation Extract:
Zaharieva IT, Calissano M, Scoto M, Preston M, Cirak S, Feng L, Collins J, Kole R, Guglieri M, Straub V, Bushby K, Ferlini A, Morgan JE, Muntoni F. Dystromirs as Serum Biomarkers for Monitoring the Disease Severity in Duchenne Muscular Dystrophy. PLoS ONE. 2013;8(11):e80263. doi:10.1371/journal.pone.0080263.

A Potential Benefit of Albinism in Astyanax Cavefish: Downregulation of the oca2 Gene Increases Tyrosine and Catecholamine Levels as an Alternative to Melanin Synthesis

Authors:
Bilandžija H, Ma L, Parkhurst A, Jeffery WR
Citation:
PLoS ONE. 2013;8(11):e80823. doi:10.1371/journal.pone.0080823
Epub:
Not Epub
Abstract:
Albinism, the loss of melanin pigmentation, has evolved in a diverse variety of cave animals but the responsible evolutionary...
Delivery Method:
microinjection
Organism or Cell Type:
Astyanax mexicanus
Citation Extract:
Bilandžija H, Ma L, Parkhurst A, Jeffery WR. A Potential Benefit of Albinism in Astyanax Cavefish: Downregulation of the oca2 Gene Increases Tyrosine and Catecholamine Levels as an Alternative to Melanin Synthesis. PLoS ONE. 2013;8(11):e80823. doi:10.1371/journal.pone.0080823.

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