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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12156 scientific papers returned from the database with the search filters currently being used below.

Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field specification

Authors:
Young RM, Hawkins TA, Cavodeassi F, Stickney HL, Schwarz Q, Lawrence LM, Wierzbicki C, Cheng BYL, Luo J, Ambrosio EM, Klosner A, Sealy IM, Rowell J, Trivedi CA, Bianco IH, Allende ML, Busch-Nentwich EM, Gestri G, Wilson SW
Citation:
eLife. 2019;8:e40093 doi:10.7554/eLife.40093
Epub:
Not Epub
Abstract:
The vertebrate eye originates from the eye field, a domain of cells specified by a small number of transcription factors. In...
Link:
https://elifesciences.org/articles/40093
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Young RM, Hawkins TA, Cavodeassi F, Stickney HL, Schwarz Q, Lawrence LM, Wierzbicki C, Cheng BYL, Luo J, Ambrosio EM, Klosner A, Sealy IM, Rowell J, Trivedi CA, Bianco IH, Allende ML, Busch-Nentwich EM, Gestri G, Wilson SW. Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field specification. eLife. 2019;8:e40093 doi:10.7554/eLife.40093.

Mutant Ahi1 affects retinal axon projection in zebrafish via toxic gain of function

Authors:
Li X-J, Zhu L, Chen L, Yan L, Perkins B, Li S, Li B, Xu HA
Citation:
Front Cell Neurosci. 2019 Mar 21;13:81. doi: 10.3389/fncel.2019.00081.
Epub:
Not Epub
Abstract:
Joubert syndrome (JBTS) is an inherited autosomal recessive disorder associated with cerebellum and brainstem malformation and...
Link:
https://www.frontiersin.org/articles/10.3389/fncel.2019.00081/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li X-J, Zhu L, Chen L, Yan L, Perkins B, Li S, Li B, Xu HA. Mutant Ahi1 affects retinal axon projection in zebrafish via toxic gain of function. Front Cell Neurosci. 2019 Mar 21;13:81. doi: 10.3389/fncel.2019.00081. .

Cell-Size-Independent Spindle Checkpoint Failure Underlies Chromosome Segregation Error in Mouse Embryos

Authors:
Vázquez-Diez C, Paim LMG, FitzHarris G
Citation:
Curr Biol. 2019 Jan 17. pii: S0960-9822(18)31676-2. doi: 10.1016/j.cub.2018.12.042. [Epub ahead of print]
Epub:
Yes
Abstract:
Chromosome segregation errors during mammalian preimplantation development cause "mosaic" embryos comprising a...
Link:
https://www.cell.com/current-biology/fulltext/S0960-9822(18)31676-2
Delivery Method:
microinjection
Organism or Cell Type:
mouse zygote
Citation Extract:
Vázquez-Diez C, Paim LMG, FitzHarris G. Cell-Size-Independent Spindle Checkpoint Failure Underlies Chromosome Segregation Error in Mouse Embryos. Curr Biol. 2019 Jan 17. pii: S0960-9822(18)31676-2. doi: 10.1016/j.cub.2018.12.042. [Epub ahead of print].

BMP signaling is required for amphioxus tail regeneration

Authors:
Liang Y, Rathnayake D, Huang S, Pathirana A, Xu Q, Zhang S
Citation:
Development. 2019 Jan 29. pii: dev.166017. doi: 10.1242/dev.166017. [Epub ahead of print]
Epub:
Yes
Abstract:
Amphioxus, a cephalochordate, is an ideal animal in which to address questions about the evolution of regenerative ability and...
Link:
http://dev.biologists.org/content/146/4/dev166017
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Branchiostoma japonicum (amphioxus)
Citation Extract:
Liang Y, Rathnayake D, Huang S, Pathirana A, Xu Q, Zhang S. BMP signaling is required for amphioxus tail regeneration. Development. 2019 Jan 29. pii: dev.166017. doi: 10.1242/dev.166017. [Epub ahead of print].

BMP signaling is required for nkx2.3-positive pharyngeal pouch progenitor specification in zebrafish

Authors:
Li L, Ning G, Yang S, Yan Y, Cao Y, Wang Q
Citation:
PLoS Genet. 2019;15(2):e1007996. https://doi.org/10.1371/journal.pgen.1007996
Epub:
Not Epub
Abstract:
Pharyngeal pouches, a series of outpocketings that bud from the foregut endoderm, are essential to the formation of...
Link:
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1007996
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li L, Ning G, Yang S, Yan Y, Cao Y, Wang Q. BMP signaling is required for nkx2.3-positive pharyngeal pouch progenitor specification in zebrafish. PLoS Genet. 2019;15(2):e1007996. https://doi.org/10.1371/journal.pgen.1007996.

Piezo1 is required for outflow tract and aortic valve development

Authors:
Faucherre A, Moha Ou Maati H, Nasr N, Pinard A, Theron A, Odelin G, Desvignes JP, Salgado D, Collod-Béroud G, Avierinos JF, Lebon G, Zaffran S, Jopling C
Citation:
J Mol Cell Cardiol. 2020 Jun;143:51-62. doi: 10.1016/j.yjmcc.2020.03.013. Epub 2020 Apr 3. PMID: 32251670
Epub:
Not Epub
Abstract:
Aims: During embryogenesis, the onset of circulatory blood flow generates a variety of hemodynamic forces which reciprocally...
Link:
https://www.jmcc-online.com/article/S0022-2828(20)30077-8/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Faucherre A, Moha Ou Maati H, Nasr N, Pinard A, Theron A, Odelin G, Desvignes JP, Salgado D, Collod-Béroud G, Avierinos JF, Lebon G, Zaffran S, Jopling C. Piezo1 is required for outflow tract and aortic valve development. J Mol Cell Cardiol. 2020 Jun;143:51-62. doi: 10.1016/j.yjmcc.2020.03.013. Epub 2020 Apr 3. PMID: 32251670.

CFTR Protects against Mycobacterium abscessus Infection by Fine-Tuning Host Oxidative Defenses

Authors:
Bernut A, Dupont C, Ogryzko NV, Neyret A, Herrmann J-L, Floto RA, Renshaw SA, Kremer L
Citation:
Cell Rep. 2019;26(7):1828-40. doi:10.1016/j.celrep.2019.01.071
Epub:
Not Epub
Abstract:
Infection by rapidly growing Mycobacterium abscessus is increasingly prevalent in cystic fibrosis (CF), a genetic disease...
Link:
https://www.sciencedirect.com/science/article/pii/S2211124719301007
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bernut A, Dupont C, Ogryzko NV, Neyret A, Herrmann J-L, Floto RA, Renshaw SA, Kremer L. CFTR Protects against Mycobacterium abscessus Infection by Fine-Tuning Host Oxidative Defenses. Cell Rep. 2019;26(7):1828-40. doi:10.1016/j.celrep.2019.01.071.

Cdh2 coordinates Myosin-II dependent internalisation of the zebrafish neural plate

Authors:
Araya C, Häkkinen H-M, Carcamo L, Cerda M, Savy T, Rookyard C, Peyriéras N, Clarke JDW
Citation:
Sci Rep. 2019;9:1835. doi:10.1038/s41598-018-38455-w
Epub:
Not Epub
Abstract:
Tissue internalisation is a key morphogenetic mechanism by which embryonic tissues generate complex internal organs and a...
Link:
https://www.nature.com/articles/s41598-018-38455-w
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Araya C, Häkkinen H-M, Carcamo L, Cerda M, Savy T, Rookyard C, Peyriéras N, Clarke JDW. Cdh2 coordinates Myosin-II dependent internalisation of the zebrafish neural plate. Sci Rep. 2019;9:1835. doi:10.1038/s41598-018-38455-w.

Novel mutations of AXIN2 identified in a Chinese Congenital Heart Disease Cohort

Authors:
Zhu M-J, Ma X-Y, Ding P-C, Tang H-F, Peng R, Lu L, Li P-Q, Qiao B, Yang X-Y, Zheng Y-F, Wang H-Y, Gao Y-Q, Chen F-S
Citation:
J Hum Genet. 2019;[Epub ahead of print] doi:10.1038/s10038-019-0572-x
Epub:
Yes
Abstract:
Congenital heart defects (CHDs), the most common congenital human birth anomalies, involves complex genetic factors. Wnt/β-...
Link:
https://www.nature.com/articles/s10038-019-0572-x
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhu M-J, Ma X-Y, Ding P-C, Tang H-F, Peng R, Lu L, Li P-Q, Qiao B, Yang X-Y, Zheng Y-F, Wang H-Y, Gao Y-Q, Chen F-S. Novel mutations of AXIN2 identified in a Chinese Congenital Heart Disease Cohort. J Hum Genet. 2019;[Epub ahead of print] doi:10.1038/s10038-019-0572-x.

tmem33 is essential for VEGF-mediated endothelial calcium oscillations and angiogenesis

Authors:
Savage AM, Kurusamy S, Chen Y, Jiang Z, Chhabria K, MacDonald RB, Kim HR, Wilson HL, van Eeden FJM, Armesilla AL, Chico TJA, Wilkinson RN
Citation:
Nat Comm. 2019;10:732. doi:10.1038/s41467-019-08590-7
Epub:
Not Epub
Abstract:
Angiogenesis requires co-ordination of multiple signalling inputs to regulate the behaviour of endothelial cells (ECs) as they...
Link:
https://www.nature.com/articles/s41467-019-08590-7
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Savage AM, Kurusamy S, Chen Y, Jiang Z, Chhabria K, MacDonald RB, Kim HR, Wilson HL, van Eeden FJM, Armesilla AL, Chico TJA, Wilkinson RN. tmem33 is essential for VEGF-mediated endothelial calcium oscillations and angiogenesis. Nat Comm. 2019;10:732. doi:10.1038/s41467-019-08590-7.

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