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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12176 scientific papers returned from the database with the search filters currently being used below.

Blockade of a Laminin-411-Notch Axis with CRISPR/Cas9 or a Nanobioconjugate Inhibits Glioblastoma Growth through Tumor-Microenvironment Cross-talk

Authors:
Sun T, Patil R, Galstyan A, Klymyshyn D, Ding H, Chesnokova A, Cavenee WK, Furnari FB, Ljubimov VA, Shatalova ES, Wagner S, Li D, Mamelak AN, Bannykh SI, Patil CG, Rudnick JD, Hu J, Grodzinski ZB, Rekechenetskiy A, Falahatian V, Lyubimov AV, Chen YL, Leoh LS, Daniels-Wells TR, Penichet ML, Holler E, Ljubimov AV, Black KL, Ljubimova JY
Citation:
Cancer Res. 2019 Mar 15;79(6):1239-1251. doi: 10.1158/0008-5472.CAN-18-2725. Epub 2019 Jan 18
Epub:
Not Epub
Abstract:
. . . There is an unmet need for the treatment of glioblastoma multiforme (GBM). The extracellular matrix, including...
Link:
http://cancerres.aacrjournals.org/content/79/6/1239
Delivery Method:
nanoparticles
Organism or Cell Type:
mice with glioblastome xenograft
Citation Extract:
Sun T, Patil R, Galstyan A, Klymyshyn D, Ding H, Chesnokova A, Cavenee WK, Furnari FB, Ljubimov VA, Shatalova ES, Wagner S, Li D, Mamelak AN, Bannykh SI, Patil CG, Rudnick JD, Hu J, Grodzinski ZB, Rekechenetskiy A, Falahatian V, Lyubimov AV, Chen YL, Leoh LS, Daniels-Wells TR, Penichet ML, Holler E, Ljubimov AV, Black KL, Ljubimova JY. Blockade of a Laminin-411-Notch Axis with CRISPR/Cas9 or a Nanobioconjugate Inhibits Glioblastoma Growth through Tumor-Microenvironment Cross-talk. Cancer Res. 2019 Mar 15;79(6):1239-1251. doi: 10.1158/0008-5472.CAN-18-2725. Epub 2019 Jan 18.

A critical role for miR-142 in alveolar epithelial lineage formation in mouse lung development

Authors:
Shrestha A, Carraro G, Nottet N, Vazquez-Armendariz AI, Susanne Herold S, Cordero J, Singh I, Jochen Wilhelm J, Barreto G, Morty R, El Agha E, Mari B, Chen C, Jin-San Zhang J-S, Chao C-M, Bellusci S
Citation:
Cell Molec Life Sci. 2019;[Epub] doi:10.1007/s00018-019-03067-8
Epub:
Yes
Abstract:
The respiratory epithelium arises from alveolar epithelial progenitors which differentiate into alveolar epithelial type 1 (AT1...
Link:
https://link.springer.com/article/10.1007%2Fs00018-019-03067-8
Organism or Cell Type:
lung explants
Citation Extract:
Shrestha A, Carraro G, Nottet N, Vazquez-Armendariz AI, Susanne Herold S, Cordero J, Singh I, Jochen Wilhelm J, Barreto G, Morty R, El Agha E, Mari B, Chen C, Jin-San Zhang J-S, Chao C-M, Bellusci S. A critical role for miR-142 in alveolar epithelial lineage formation in mouse lung development. Cell Molec Life Sci. 2019;[Epub] doi:10.1007/s00018-019-03067-8.

Zebrafish Model for Non-Syndromic X-linked Sensorineural Deafness, DFNX1

Authors:
DeSmidt AA, Zou B, Grati M, Yan D, Mittal R, Yao Q, Richmond MT, Denyer S, Liu XZ, Lu Z
Citation:
Anat Rec (Hoboken). 2019 Mar 15. doi: 10.1002/ar.24115. [Epub ahead of print]
Epub:
Yes
Abstract:
Hereditary deafness is often a neurosensory disorder and affects the quality of life of humans. Only three X-linked genes (POU...
Link:
https://onlinelibrary.wiley.com/doi/abs/10.1002/ar.24115
Organism or Cell Type:
zebrafish
Citation Extract:
DeSmidt AA, Zou B, Grati M, Yan D, Mittal R, Yao Q, Richmond MT, Denyer S, Liu XZ, Lu Z. Zebrafish Model for Non-Syndromic X-linked Sensorineural Deafness, DFNX1. Anat Rec (Hoboken). 2019 Mar 15. doi: 10.1002/ar.24115. [Epub ahead of print].

cMet signaling functions during zebrafish hindbrain development

Authors:
Elsen GE, Choi LY, Prince VE, Ho RK
Citation:
Dev Biol. 2008;329(2):541. doi:10.1016/j.ydbio.2008.05.270
Epub:
Not Epub
Abstract:
During development, cMet signaling regulates a range of cellular processes, including growth, survival and migration (...
Link:
https://www.sciencedirect.com/science/article/pii/S0012160608006015
Organism or Cell Type:
zebrafish
Citation Extract:
Elsen GE, Choi LY, Prince VE, Ho RK. cMet signaling functions during zebrafish hindbrain development. Dev Biol. 2008;329(2):541. doi:10.1016/j.ydbio.2008.05.270.

Generation of anisotropic strain dysregulates wild-type cell division at the interface between host and oncogenic tissue

Authors:
Moruzzi M, Nestor-Bergmann A, Goddard GK, Tarannum N, Brennan K, Woolner S
Citation:
Curr Biol. 2021 Aug 9;31(15):3409-3418.e6. doi: 10.1016/j.cub.2021.05.023. Epub 2021 Jun 9. PMID: 34111402; PMCID: PMC8360906
Epub:
Not Epub
Abstract:
Epithelial tissues are highly sensitive to anisotropies in mechanical force, with cells altering fundamental behaviors, such as...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC8360906/
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Moruzzi M, Nestor-Bergmann A, Goddard GK, Tarannum N, Brennan K, Woolner S. Generation of anisotropic strain dysregulates wild-type cell division at the interface between host and oncogenic tissue. Curr Biol. 2021 Aug 9;31(15):3409-3418.e6. doi: 10.1016/j.cub.2021.05.023. Epub 2021 Jun 9. PMID: 34111402; PMCID: PMC8360906.

A Smart Imaging Workflow for Organ-Specific Screening in a Cystic Kidney Zebrafish Disease Model

Authors:
Pandey G, Westhoff JH, Schaefer F, Gehrig L
Citation:
Int J Med Sci. 2019;20(6):1290. doi:10.3390/ijms20061290
Epub:
Not Epub
Abstract:
The zebrafish is being increasingly used in biomedical research and drug discovery to conduct large-scale compound screening....
Link:
https://www.mdpi.com/1422-0067/20/6/1290/htm
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pandey G, Westhoff JH, Schaefer F, Gehrig L. A Smart Imaging Workflow for Organ-Specific Screening in a Cystic Kidney Zebrafish Disease Model. Int J Med Sci. 2019;20(6):1290. doi:10.3390/ijms20061290.

FoxN3 is necessary for the development of the interatrial septum, the ventricular trabeculae and the muscles at the head/trunk interface in the African clawed frog, Xenopus laevis (Lissamphibia: Anura: Pipidae)

Authors:
Naumann B, Schmidt J, Olsson L
Citation:
Dev Dyn. 2019 Mar 11. doi: 10.1002/dvdy.25. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: Fox genes are a large family of transcription factors that play diverse roles in the immune system, metabolism,...
Link:
https://onlinelibrary.wiley.com/doi/abs/10.1002/dvdy.25
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Naumann B, Schmidt J, Olsson L. FoxN3 is necessary for the development of the interatrial septum, the ventricular trabeculae and the muscles at the head/trunk interface in the African clawed frog, Xenopus laevis (Lissamphibia: Anura: Pipidae). Dev Dyn. 2019 Mar 11. doi: 10.1002/dvdy.25. [Epub ahead of print].

The Frog Xenopus as a Model to Study Joubert Syndrome: The Case of a Human Patient With Compound Heterozygous Variants in PIBF1

Authors:
Ott T, Kaufmann L, Granzow M, Hinderhofer K, Bartram CR, Theiß S, Seitz A, Paramasivam N, Schulz A, Moog U, Blum M, Evers CM
Citation:
Front Physiol. 2019 Feb 25;10:134. doi: 10.3389/fphys.2019.00134. eCollection 2019
Epub:
Not Epub
Abstract:
Joubert syndrome (JS) is a congenital autosomal-recessive or-in rare cases-X-linked inherited disease. The diagnostic hallmark...
Link:
https://www.frontiersin.org/articles/10.3389/fphys.2019.00134/full
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ott T, Kaufmann L, Granzow M, Hinderhofer K, Bartram CR, Theiß S, Seitz A, Paramasivam N, Schulz A, Moog U, Blum M, Evers CM. The Frog Xenopus as a Model to Study Joubert Syndrome: The Case of a Human Patient With Compound Heterozygous Variants in PIBF1. Front Physiol. 2019 Feb 25;10:134. doi: 10.3389/fphys.2019.00134. eCollection 2019.

Ultrasensitive detection of microRNA using an array of Au nanowires deposited within the channels of a porous anodized alumina membrane

Authors:
Li C, He L, Jiang S, Mo R, Yan X, Qian Z-J, Zhou C, Sun S, Hong P, Huang Y
Citation:
Elecrochem Comm. 2019;[Epub ahead of print] doi:10.1016/j.elecom.2019.03.008
Epub:
Yes
Abstract:
A new nanopore array/Au electrode was fabricated and applied to the detection of microRNA. The electrode was prepared via...
Link:
https://www.sciencedirect.com/science/article/pii/S1388248119300724
Citation Extract:
Li C, He L, Jiang S, Mo R, Yan X, Qian Z-J, Zhou C, Sun S, Hong P, Huang Y. Ultrasensitive detection of microRNA using an array of Au nanowires deposited within the channels of a porous anodized alumina membrane. Elecrochem Comm. 2019;[Epub ahead of print] doi:10.1016/j.elecom.2019.03.008.

Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly

Authors:
Lahrouchi N, George A, Ratbi I, Schneider R, Elalaoui SC, Moosa S, Bharti S, Sharma R, Abu-Asab M, Onojafe F, Adadi N, Lodder EM, Laarabi F-Z, Lamsyah Y, Elorch H, Chebbar I, Postma AV, Lougaris V, Plebani A, Altmueller J, Kyrieleis H, Meiner V, McNeill H, Bharti K, Lyonnet S, Wollnik B, Henrion-Caude A, Berraho A, Hildebrandt F, Bezzina CR, Brooks BP, Sefiani A
Citation:
Nat Comm. 2019;10:1180. doi:10.1038/s41467-019-08547-w
Epub:
Not Epub
Abstract:
A failure in optic fissure fusion during development can lead to blinding malformations of the eye. Here, we report a syndrome...
Link:
https://www.nature.com/articles/s41467-019-08547-w
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lahrouchi N, George A, Ratbi I, Schneider R, Elalaoui SC, Moosa S, Bharti S, Sharma R, Abu-Asab M, Onojafe F, Adadi N, Lodder EM, Laarabi F-Z, Lamsyah Y, Elorch H, Chebbar I, Postma AV, Lougaris V, Plebani A, Altmueller J, Kyrieleis H, Meiner V, McNeill H, Bharti K, Lyonnet S, Wollnik B, Henrion-Caude A, Berraho A, Hildebrandt F, Bezzina CR, Brooks BP, Sefiani A. Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly. Nat Comm. 2019;10:1180. doi:10.1038/s41467-019-08547-w.

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