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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12351 scientific papers returned from the database with the search filters currently being used below.
There are 12351 scientific papers returned from the database with the search filters currently being used below.
Abnormal cerebellar development and ataxia in CARP VIII morphant zebrafish
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Citation:
Hum Mol Genet. 2012;[Epub ahead of print] doi:10.1093/hmg/dds438 Epub:
Not Epub Abstract:
Congenital ataxia and mental retardation are mainly caused by variations in the genes that affect brain development. Recent... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Aspatwar A, Tolvanen MEE, Jokitalo E, Parikka M, Ortutay C, Harjula S-K E, Rämet M, Vihinen M, Parkkila S. Abnormal cerebellar development and ataxia in CARP VIII morphant zebrafish. Hum Mol Genet. 2012;[Epub ahead of print] doi:10.1093/hmg/dds438. |
Acetylcholinesterase is required for neuronal and muscular development in the zebrafish embryo
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Citation:
Nat Neurosci. 2002 Feb;5(2):111-8 Epub:
Not Epub Abstract:
The neurotransmitter acetylcholine (ACh) has a crucial role in central and neuromuscular synapses of the cholinergic system.... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Behra M, Cousin X, Bertrand C, Vonesch JL, Biellmann D, Chatonnet A, Strahle U. Acetylcholinesterase is required for neuronal and muscular development in the zebrafish embryo. Nat Neurosci. 2002 Feb;5(2):111-8. |
Ambra1 knockdown in zebrafish leads to incomplete development due to severe defects in organogenesis
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Citation:
Autophagy. 2013 Jan 24;9(4). [Epub ahead of print] Epub:
Not Epub Abstract:
AMBRA1 is a positive regulator of the BECN1-dependent program of autophagy recently identified in mouse. In this study, we... Organism or Cell Type:
zebrafish Citation Extract: Benato F, Skobo T, Gioacchini G, Moro I, Ciccosanti F, Piacentini M, Fimia GM, Carnevali O, Valle LD. Ambra1 knockdown in zebrafish leads to incomplete development due to severe defects in organogenesis. Autophagy. 2013 Jan 24;9(4). [Epub ahead of print]. |
Antisense Antibiotics: A Brief Review of Novel Target Discovery and Delivery
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Citation:
Curr Drug Discov Technol. 2010 Sep 14. [Epub ahead of print] Epub:
Not Epub Abstract:
The nightmare of multi-drug resistant bacteria will still haunt if no panacea is ever found. Efforts on seeking desirable... Organism or Cell Type:
Bacteria (review) Citation Extract: Bai H, Xue X, Hou Z, Zhou Y, Meng J, Luo X. Antisense Antibiotics: A Brief Review of Novel Target Discovery and Delivery. Curr Drug Discov Technol. 2010 Sep 14. [Epub ahead of print]. |
Antisense oligonucleotides targeted to the p53 gene modulate rat liver regeneration
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Citation:
Drug Metab. And Disp. 2000. 28(2):131-138 Epub:
Not Epub Abstract:
The rapidly proliferating cells of the regenerating liver after partial hepatectomy (PH) present a reproducible in vivo model... Delivery Method:
in vivo: injection Organism or Cell Type:
rats, Sprague Dawley Citation Extract: Arora V, Iversen PL. Antisense oligonucleotides targeted to the p53 gene modulate rat liver regeneration. Drug Metab. And Disp. 2000. 28(2):131-138. |
ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor 1
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Citation:
Nat Med. 2012;[Epub ahead of print] doi:10.1038/nm.2759 Epub:
Not Epub Abstract:
Despite the clear major contribution of hyperlipidemia to the prevalence of cardiovascular disease in the developed world, the... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Avraham-Davidi I, Ely Y, Pham VN, Castranova D, Grunspan M, Malkinson G, Gibbs-Bar L, Mayseless O, Allmog G, Lo B, Warren CM, Chen TT, Ungos J, Kidd K, Shaw K, Rogachev I, Wan W, Murphy PM, Farber SA, Carmel L, Shelness GS, Iruela-Arispe ML, Weinstein BM, Yaniv K. ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor 1. Nat Med. 2012;[Epub ahead of print] doi:10.1038/nm.2759. |
Bioavailability and efficacy of antisense morpholino oligomers targeted to c-myc and cytochrome P-450 3A2 following oral administration in rats
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Citation:
J Pharm Sci. 2002 Apr;91(4):1009-18 Epub:
Not Epub Abstract:
Antisense phosphorodiamidate Morpholino oligomers (PMO) are resistant to degradation by cellular hydrolases, DNases, RNases,... Delivery Method:
in vivo: injection Organism or Cell Type:
rats, Sprague Dawley Citation Extract: Arora V, Knapp DC, Reddy MT, Weller DD, Iversen PL.. Bioavailability and efficacy of antisense morpholino oligomers targeted to c-myc and cytochrome P-450 3A2 following oral administration in rats. J Pharm Sci. 2002 Apr;91(4):1009-18. |
Brain selective transgene expression in zebrafish using an NRSE derived motif
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Citation:
Front Neur Circuits. 2012;6(00110). doi:10.3389/fncir.2012.00110 Epub:
Not Epub Abstract:
Transgenic technologies enable the manipulation and observation of circuits controlling behavior by permitting expression of... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Bergeron SA, Hannan MC, Codore H, Fero K, Li G, Moak ZB, Yokogawa T, Burgess HA. Brain selective transgene expression in zebrafish using an NRSE derived motif. Front Neur Circuits. 2012;6(00110). doi:10.3389/fncir.2012.00110. |
Brother of cdo (umleitung) is cell-autonomously required for Hedgehog-mediated ventral CNS patterning in the zebrafish
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Citation:
Development. 2011 Jan;138(1):75-85. Epub 2010 Nov 29 Epub:
Not Epub Abstract:
The transmembrane protein Brother of Cdo (Boc) has been implicated in Shh-mediated commissural axon guidance, and can both... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Bergeron SA, Tyurina OV, Miller E, Bagas A, Karlstrom RO. Brother of cdo (umleitung) is cell-autonomously required for Hedgehog-mediated ventral CNS patterning in the zebrafish. Development. 2011 Jan;138(1):75-85. Epub 2010 Nov 29. |
c-Myc antisense limits rat liver regeneration and indicates role for c-Myc in regulating cytochrome P-450 3A activity
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Citation:
Exp Ther 2000 Mar 292(3):921-8 Epub:
Not Epub Abstract:
Expression of c-myc protein is associated with cell proliferation. The present study uses antisense oligomers to inhibit c-myc... Delivery Method:
Injection Organism or Cell Type:
rats, Sprague Dawley Citation Extract: Arora V, Knapp DC, Smith BL, Statdfield ML, Stein DA, Reddy MT, Weller DD, Iversen PL. c-Myc antisense limits rat liver regeneration and indicates role for c-Myc in regulating cytochrome P-450 3A activity. Exp Ther 2000 Mar 292(3):921-8. |