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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Targeted mutation of the talpid3 gene in zebrafish reveals its conserved requirement for ciliogenesis and Hedgehog signalling across the vertebrates

Authors:
Ben J, Elworthy S, Ng AS, van Eeden F, Ingham PW
Citation:
Development. 2011 Nov;138(22):4969-78
Epub:
Not Epub
Abstract:
Using zinc-finger nuclease-mediated mutagenesis, we have generated mutant alleles of the zebrafish orthologue of the chicken...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ben J, Elworthy S, Ng AS, van Eeden F, Ingham PW. Targeted mutation of the talpid3 gene in zebrafish reveals its conserved requirement for ciliogenesis and Hedgehog signalling across the vertebrates. Development. 2011 Nov;138(22):4969-78.

TBP2, a vertebrate-specific member of the TBP family, is required in embryonic development of zebrafish

Authors:
Bartfai R, Balduf C, Hilton T, Rathmann Y, Hadzhiev Y, Tora L, Orban L, Muller F
Citation:
Curr Biol. 2004 Apr 6;14(7):593-8.
Epub:
Not Epub
Abstract:
TATA binding protein (TBP) is a key regulator of RNA polymerase transcription. It binds to core promoters, often in large...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bartfai R, Balduf C, Hilton T, Rathmann Y, Hadzhiev Y, Tora L, Orban L, Muller F. TBP2, a vertebrate-specific member of the TBP family, is required in embryonic development of zebrafish. Curr Biol. 2004 Apr 6;14(7):593-8..

Tenascin-R as a repellent guidance molecule for developing optic axons in zebrafish

Authors:
Becker CG, Schweitzer J, Feldner J, Becker T, Schachner M
Citation:
J Neurosci. 2003 Jul 16;23(15):6232-7
Epub:
Not Epub
Abstract:
To investigate the role of tenascin-R in nervous system development, we studied axon pathfinding in the developing optic system...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Becker CG, Schweitzer J, Feldner J, Becker T, Schachner M. Tenascin-R as a repellent guidance molecule for developing optic axons in zebrafish. J Neurosci. 2003 Jul 16;23(15):6232-7.

The B-cell maturation factor Blimp-1 specifies vertebrate slow-twitch muscle fiber identity in response to Hedgehog signaling

Authors:
Baxendale S, Davison C, Muxworthy C, Wolff C, Ingham PW, Roy S
Citation:
Nat Genet. 2004 Jan;36(1):88-93. Epub 2003 Dec 21
Epub:
Not Epub
Abstract:
Vertebrate skeletal muscles comprise distinct fiber types that differ in their morphology, contractile function, mitochondrial...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Baxendale S, Davison C, Muxworthy C, Wolff C, Ingham PW, Roy S. The B-cell maturation factor Blimp-1 specifies vertebrate slow-twitch muscle fiber identity in response to Hedgehog signaling. Nat Genet. 2004 Jan;36(1):88-93. Epub 2003 Dec 21.

The Ca2+-induced methyltransferase xPRMT1b controls neural fate in amphibian embryo

Authors:
Batut J, Vandel L, Leclerc C, Daguzan C, Moreau M, Neant I
Citation:
Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15128-15133. Epub 2005 Oct 7
Epub:
Not Epub
Abstract:
We have previously shown that an increase in intracellular Ca(2+) is both necessary and sufficient to commit ectoderm to a...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Batut J, Vandel L, Leclerc C, Daguzan C, Moreau M, Neant I. The Ca2+-induced methyltransferase xPRMT1b controls neural fate in amphibian embryo. Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15128-15133. Epub 2005 Oct 7.

The centriolar satellite protein SSX2IP promotes centrosome maturation

Authors:
Bärenz F, Inoue D, Yokoyama H, Tegha-Dunghu J, Freiss S, Draeger S, Mayilo D, Cado I, Merker S, Klinger M, Hoeckendorf B, Pilz S, Hupfeld K, Steinbeisser H, Lorenz H, Ruppert T, Wittbrodt J, Gruss OJ
Citation:
J Cell Biol. 2013 Jul 8;202(1):81-95. doi: 10.1083/jcb.201302122. Epub 2013 Jul 1
Epub:
Not Epub
Abstract:
Meiotic maturation in vertebrate oocytes is an excellent model system for microtubule reorganization during M-phase spindle...
Delivery Method:
Microinjection
Organism or Cell Type:
medaka
Citation Extract:
Bärenz F, Inoue D, Yokoyama H, Tegha-Dunghu J, Freiss S, Draeger S, Mayilo D, Cado I, Merker S, Klinger M, Hoeckendorf B, Pilz S, Hupfeld K, Steinbeisser H, Lorenz H, Ruppert T, Wittbrodt J, Gruss OJ. The centriolar satellite protein SSX2IP promotes centrosome maturation. J Cell Biol. 2013 Jul 8;202(1):81-95. doi: 10.1083/jcb.201302122. Epub 2013 Jul 1.

The Ciliopathy Gene cc2d2a controls Zebrafish Photoreceptor Outer Segment Development Through a Role in Rab8-dependent Vesicle Trafficking

Authors:
Bachmann-Gagescu R, Phelps IG, Stearns G, Link BA, Brockerhoff SE, Moens CB, Doherty D
Citation:
Hum Mol Genet. 2011 Aug 4. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Ciliopathies are a genetically and phenotypically heterogeneous group of human developmental disorders whose root cause is the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bachmann-Gagescu R, Phelps IG, Stearns G, Link BA, Brockerhoff SE, Moens CB, Doherty D. The Ciliopathy Gene cc2d2a controls Zebrafish Photoreceptor Outer Segment Development Through a Role in Rab8-dependent Vesicle Trafficking. Hum Mol Genet. 2011 Aug 4. [Epub ahead of print].

The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation

Authors:
Becker-Heck A, Zohn IE, Okabe N, Pollock A, Lenhart KB, Sullivan-Brown J, McSheene J, Loges NT, Olbrich H, Haeffner K, Fliegauf M, Horvath J, Reinhardt R, Nielsen KG, Marthin JK, Baktai G, Anderson KV, Geisler R, Niswander L, Omran H, Burdine RD
Citation:
Nat Genet. 2010 Dec 5. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Primary ciliary dyskinesia (PCD) is a genetically heterogeneous autosomal recessive disorder characterized by recurrent...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Becker-Heck A, Zohn IE, Okabe N, Pollock A, Lenhart KB, Sullivan-Brown J, McSheene J, Loges NT, Olbrich H, Haeffner K, Fliegauf M, Horvath J, Reinhardt R, Nielsen KG, Marthin JK, Baktai G, Anderson KV, Geisler R, Niswander L, Omran H, Burdine RD. The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation. Nat Genet. 2010 Dec 5. [Epub ahead of print].

The ERRalpha orphan nuclear receptor controls morphogenetic movements during zebrafish gastrulation

Authors:
Bardet PL, Horard B, Laudet V, Vanacker JM
Citation:
Dev Biol. 2005 May 1;281(1):102-11
Epub:
Not Epub
Abstract:
Gastrulation is a process involving cellular commitment and movements whereby the three fundamental germ layers are established...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bardet PL, Horard B, Laudet V, Vanacker JM. The ERRalpha orphan nuclear receptor controls morphogenetic movements during zebrafish gastrulation. Dev Biol. 2005 May 1;281(1):102-11.

The function of Xenopus germ cell nuclear factor (xGCNF) in morphogenetic movements during neurulation.

Authors:
Barreto G, Reintsch W, Kaufmann C, Dreyer C.
Citation:
Dev Biol 2003 May 15;257(2):329-42
Epub:
Not Epub
Abstract:
The germ cell nuclear factor (GCNF, NR6A1) is a nuclear orphan receptor first described in the mouse testis and subsequently...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Barreto G, Reintsch W, Kaufmann C, Dreyer C.. The function of Xenopus germ cell nuclear factor (xGCNF) in morphogenetic movements during neurulation.. Dev Biol 2003 May 15;257(2):329-42.

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