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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Role of Zebrafish Lbx2 in Embryonic Lateral Line Development

Authors:
Chen X, Lou Q, He J, Yin Z
Citation:
PLoS ONE. 2011;6(12): e29515. doi:10.1371/journal.pone.0029515
Epub:
Not Epub
Abstract:
Cellular functions and survival are dependent on a tightly controlled redox potential. Currently, an increasing amount of data...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen X, Lou Q, He J, Yin Z. Role of Zebrafish Lbx2 in Embryonic Lateral Line Development. PLoS ONE. 2011;6(12): e29515. doi:10.1371/journal.pone.0029515.

Splicing factors PTBP1 and PTBP2 promote proliferation and migration of glioma cell lines

Authors:
Cheung HC, Hai T, Zhu W, Baggerly KA, Tsavachidis S, Krahe R, Cote GJ
Citation:
Brain. 2009 Jun 8. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Polypyrimidine tract-binding protein 1 (PTBP1) is a multi-functional RNA-binding protein that is aberrantly overexpressed in...
Delivery Method:
Scrape Delivery
Organism or Cell Type:
cell culture: glioma lines U 251 and LN 229
Citation Extract:
Cheung HC, Hai T, Zhu W, Baggerly KA, Tsavachidis S, Krahe R, Cote GJ. Splicing factors PTBP1 and PTBP2 promote proliferation and migration of glioma cell lines. Brain. 2009 Jun 8. [Epub ahead of print].

Syndecan-2 is essential for angiogenic sprouting during zebrafish development

Authors:
Chen E, Hermanson S, Ekker SC
Citation:
Blood. 2004 Mar 1;103(5):1710-9. Epub 2003 Oct 30.
Epub:
Not Epub
Abstract:
We used a morpholino-based gene targeting screen to identify a novel protein essential for vascular development using the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen E, Hermanson S, Ekker SC. Syndecan-2 is essential for angiogenic sprouting during zebrafish development. Blood. 2004 Mar 1;103(5):1710-9. Epub 2003 Oct 30..

Synthesis and in Vitro Characterization of a Dendrimer-MORF Conjugate for Amplification Pretargeting

Authors:
Chen X, Dou S, Liu G, Liu X, Wang Y, Chen L, Rusckowski M, Hnatowich DJ
Citation:
Bioconjug Chem. 2008 Jul 23. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Amplification pretargeting can play an important role in molecular imaging by significantly increasing the accumulation of...
Citation Extract:
Chen X, Dou S, Liu G, Liu X, Wang Y, Chen L, Rusckowski M, Hnatowich DJ. Synthesis and in Vitro Characterization of a Dendrimer-MORF Conjugate for Amplification Pretargeting. Bioconjug Chem. 2008 Jul 23. [Epub ahead of print].

The essential vertebrate ABCE1 protein interacts with eukaryotic initiation factors

Authors:
Chen ZQ, Dong J, Ishimura A, Daar I, Hinnebusch A, Dean M
Citation:
J Biol Chem. 2006 Mar 17;281(11):7452-7. Epub 2006 Jan 18
Epub:
Not Epub
Abstract:
The ABCE1 gene is a member of the ATP-binding cassette (ABC) multigene family and is composed of two nucleotide binding domains...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chen ZQ, Dong J, Ishimura A, Daar I, Hinnebusch A, Dean M. The essential vertebrate ABCE1 protein interacts with eukaryotic initiation factors. J Biol Chem. 2006 Mar 17;281(11):7452-7. Epub 2006 Jan 18.

The mitochondrial respiratory chain controls intracellular calcium signaling and NFAT activity essential for heart formation in Xenopus laevis

Authors:
Chen Y, Yuen WH, Fu J, Huang G, Melendez AJ, Ibrahim FB, Lu H, Cao X
Citation:
Mol Cell Biol. 2007 Sep;27(18):6420-32. Epub 2007 Jul 16
Epub:
Not Epub
Abstract:
The mitochondrial respiratory chain (MRC) plays crucial roles in cellular energy production. However, its function in early...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chen Y, Yuen WH, Fu J, Huang G, Melendez AJ, Ibrahim FB, Lu H, Cao X. The mitochondrial respiratory chain controls intracellular calcium signaling and NFAT activity essential for heart formation in Xenopus laevis. Mol Cell Biol. 2007 Sep;27(18):6420-32. Epub 2007 Jul 16.

The physiological role of CTGF/CCN2 in zebrafish notochond development and biological analysis of the proximal promoter region

Authors:
Chiou MJ, Chao TT, Wu JL, Kuo CM, Chen JY
Citation:
Biochem Biophys Res Commun. 2006 Oct 20;349(2):750-8. Epub 2006 Aug 28.
Epub:
Not Epub
Abstract:
During mouse embryogenesis, CTGF/CCN2 is expressed in zones containing hypertrophic chondroctyes and calcifying cartilage such...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chiou MJ, Chao TT, Wu JL, Kuo CM, Chen JY. The physiological role of CTGF/CCN2 in zebrafish notochond development and biological analysis of the proximal promoter region. Biochem Biophys Res Commun. 2006 Oct 20;349(2):750-8. Epub 2006 Aug 28..

The toxic effect of Amiodarone on valve formation in the developing heart of zebrafish embryos

Authors:
Chen YH, Hsu RJ, Chen TY, Huang YK, Lee HC, Hu SC, Harn HJ, Jeng JR, Sun CK, Lin SZ, Tsai HJ
Citation:
Reprod Toxicol. 2011 Dec 29. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Amiodarone is a class D drug given to treat arrhythmia, including pregnant women, but its effects on the developing...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen YH, Hsu RJ, Chen TY, Huang YK, Lee HC, Hu SC, Harn HJ, Jeng JR, Sun CK, Lin SZ, Tsai HJ. The toxic effect of Amiodarone on valve formation in the developing heart of zebrafish embryos. Reprod Toxicol. 2011 Dec 29. [Epub ahead of print].

The Transcription Factor MEF2 Directs Developmental Visually Driven Functional and Structural Metaplasticity

Authors:
Chen SX, Cherry A, Tari PK, Podgorski K, Kwong YKK, Haas K
Citation:
Cell. 2012;151(1):41–55 doi:10.1016/j.cell.2012.08.028
Epub:
Not Epub
Abstract:
Natural sensory input shapes both structure and function of developing neurons, but how early experience-driven morphological...
Delivery Method:
Vivo-Morpholino and seperately electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chen SX, Cherry A, Tari PK, Podgorski K, Kwong YKK, Haas K. The Transcription Factor MEF2 Directs Developmental Visually Driven Functional and Structural Metaplasticity. Cell. 2012;151(1):41–55 doi:10.1016/j.cell.2012.08.028.

The voltage-gated calcium channel CACNB2 (β2.1) protein is required in the heart for control of cell proliferation and heart tube integrity

Authors:
Chernyavskaya Y, Ebert AM, Milligan E, Garrity DM
Citation:
Dev Dyn. 2012 Jan 23. doi: 10.1002/dvdy.23746. [Epub ahead of print]
Epub:
Not Epub
Abstract:
L-type calcium channels (LTCC) regulate calcium entry into cardiomyocytes. CACNB2 (β2) LTCC auxiliary subunits traffic the pore...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chernyavskaya Y, Ebert AM, Milligan E, Garrity DM. The voltage-gated calcium channel CACNB2 (β2.1) protein is required in the heart for control of cell proliferation and heart tube integrity. Dev Dyn. 2012 Jan 23. doi: 10.1002/dvdy.23746. [Epub ahead of print].

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