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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

p53 isoform {Delta}113p53 is a p53 target gene that antagonizes p53 apoptotic activity via BclxL activation in zebrafish

Authors:
Chen J, Ng SM, Chang C, Zhang Z, Bourdon JC, Lane DP, Peng J
Citation:
Genes Dev. 2009 Feb 1;23(3):278-290
Epub:
Not Epub
Abstract:
p53 is a well-known tumor suppressor and is also involved in processes of organismal aging and developmental control. A recent...
Organism or Cell Type:
zebrafish
Citation Extract:
Chen J, Ng SM, Chang C, Zhang Z, Bourdon JC, Lane DP, Peng J. p53 isoform {Delta}113p53 is a p53 target gene that antagonizes p53 apoptotic activity via BclxL activation in zebrafish. Genes Dev. 2009 Feb 1;23(3):278-290.

Paraxial protocadherin mediates cell sorting and tissue morphogenesis by regulating C-cadherin adhesion activity

Authors:
Chen X, Gumbiner BM
Citation:
J Cell Biol. 2006 Jul 17;174(2):301-13
Epub:
Not Epub
Abstract:
Little is known about how protocadherins function in cell adhesion and tissue development. Paraxial protocadherin (PAPC)...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chen X, Gumbiner BM. Paraxial protocadherin mediates cell sorting and tissue morphogenesis by regulating C-cadherin adhesion activity. J Cell Biol. 2006 Jul 17;174(2):301-13.

Patterning of angiogenesis in the zebrafish embryo

Authors:
Childs S, Chen JN, Garrity DM, Fishman MC
Citation:
Development. 2002 Feb;129(4):973-8
Epub:
Not Epub
Abstract:
Little is known about how vascular patterns are generated in the embryo. The vasculature of the zebrafish trunk has an...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Childs S, Chen JN, Garrity DM, Fishman MC. Patterning of angiogenesis in the zebrafish embryo. Development. 2002 Feb;129(4):973-8.

Polymer Nanoparticle-Mediated Delivery of MicroRNA Inhibition and Alternative Splicing

Authors:
Cheng CJ, Saltzman WM
Citation:
Mol Pharm. 2012 Apr 18. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The crux of current RNA-based therapeutics relies on association of synthetic nucleic acids with cellular RNA targets....
Delivery Method:
Nanoparticle
Organism or Cell Type:
cell culture: human cancer cells
Citation Extract:
Cheng CJ, Saltzman WM. Polymer Nanoparticle-Mediated Delivery of MicroRNA Inhibition and Alternative Splicing. Mol Pharm. 2012 Apr 18. [Epub ahead of print].

Progranulin modulates zebrafish motoneuron development in vivo and rescues truncation defects associated with knockdown of Survival motor neuron 1

Authors:
Chitramuthu BP, Baranowski DC, Kay DG, Bateman A, Bennett HP
Citation:
Mol Neurodegener. 2010 Oct 14;5(1):41. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Progranulin (PGRN) encoded by the GRN gene, is a secreted glycoprotein growth factor that has been implicated in...
Organism or Cell Type:
zebrafish
Citation Extract:
Chitramuthu BP, Baranowski DC, Kay DG, Bateman A, Bennett HP. Progranulin modulates zebrafish motoneuron development in vivo and rescues truncation defects associated with knockdown of Survival motor neuron 1. Mol Neurodegener. 2010 Oct 14;5(1):41. [Epub ahead of print].

Progress towards a method of targeted protein knockdown in Fundulus heteroclitus

Authors:
Choe KP, Stidham J, Evans DH
Citation:
The Bulletin, MDI Biological Laboratory V. 45, 2006
Epub:
Not Epub
Abstract:
The isolated opercular epithelium of killifish, Fundulus heteroclitus, has been an electrophysiological model for elucidating...
Delivery Method:
Endo-Porter
Organism or Cell Type:
Fundulus heteroclitus
Citation Extract:
Choe KP, Stidham J, Evans DH. Progress towards a method of targeted protein knockdown in Fundulus heteroclitus. The Bulletin, MDI Biological Laboratory V. 45, 2006.

Protocadherin-17 function in zebrafish retinal development

Authors:
Chen Y, Londraville R, Brickner S, El-Shaar L, Fankhauser K, Dearth C, Fulton L, Sochacka A, Bhattarai S, Marrs JA, Liu Q
Citation:
Dev Neurobiol. 2012 Aug 28. doi: 10.1002/dneu.22053. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Cadherin cell adhesion molecules play crucial roles in vertebrate development including the development of the retina. Most...
Delivery Method:
microinjection or Vivo-Morpholino injection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen Y, Londraville R, Brickner S, El-Shaar L, Fankhauser K, Dearth C, Fulton L, Sochacka A, Bhattarai S, Marrs JA, Liu Q. Protocadherin-17 function in zebrafish retinal development. Dev Neurobiol. 2012 Aug 28. doi: 10.1002/dneu.22053. [Epub ahead of print].

PRSS23 is essential for the Snail-dependent endothelial to mesenchymal transition during valvulogenesis in zebrafish

Authors:
Chen IH, Wang HH, Hsieh YS, Huang WC, Yeh HI, Chuang YJ
Citation:
Cardiovasc Res. 2012 Dec 4. [Epub ahead of print]
Epub:
Not Epub
Abstract:
AIM: Cardiac valve disease is a common cause of congenital heart failure. Cardiac valve development requires a complex...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen IH, Wang HH, Hsieh YS, Huang WC, Yeh HI, Chuang YJ. PRSS23 is essential for the Snail-dependent endothelial to mesenchymal transition during valvulogenesis in zebrafish. Cardiovasc Res. 2012 Dec 4. [Epub ahead of print].

Repression of RNA polymerase II elongation in vivo is critically dependent on the C-terminus of Spt5

Authors:
Chen H, Contreras X, Yamaguchi Y, Handa H, Peterlin BM, Guo S
Citation:
PLoS One. 2009 Sep 9;4(9):e6918
Epub:
Not Epub
Abstract:
The stalling of RNA polymerase II (RNAPII) at the promoters of many genes, including developmental regulators, stress-...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen H, Contreras X, Yamaguchi Y, Handa H, Peterlin BM, Guo S. Repression of RNA polymerase II elongation in vivo is critically dependent on the C-terminus of Spt5. PLoS One. 2009 Sep 9;4(9):e6918.

Retinoic acid signaling is essential for pancreas development and promotes endocrine at the expense of exocrine cell differentiation in Xenopus

Authors:
Chen Y, Pan FC, Brandes N, Afelik S, Solter M, Pieler T
Citation:
Dev Biol. 2004 Jul 1;271(1):144-60
Epub:
Not Epub
Abstract:
How and when the vertebrate endoderm is first subdivided into discrete progenitor cell populations that will give rise to the...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chen Y, Pan FC, Brandes N, Afelik S, Solter M, Pieler T. Retinoic acid signaling is essential for pancreas development and promotes endocrine at the expense of exocrine cell differentiation in Xenopus. Dev Biol. 2004 Jul 1;271(1):144-60.

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