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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Links between tumor suppressors: p53 is required for TGF-beta gene responses by cooperating with Smads.

Authors:
Cordenonsi M, Dupont S, Maretto S, Insinga A, Imbriano C, Piccolo S.
Citation:
Cell. 2003 May 2;113(3):301-14.
Epub:
Not Epub
Abstract:
The p53 tumor suppressor belongs to a family of proteins that sense multiple cellular inputs to regulate cell proliferation,...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Cordenonsi M, Dupont S, Maretto S, Insinga A, Imbriano C, Piccolo S.. Links between tumor suppressors: p53 is required for TGF-beta gene responses by cooperating with Smads.. Cell. 2003 May 2;113(3):301-14..

Local tissue interactions across the dorsal midline of the forebrain establish CNS laterality.

Authors:
Concha ML, Russell C, Regan JC, Tawk M, Sidi S, Gilmour DT, Kapsimali M, Sumoy L, Goldstone K, Amaya E, Kimelman D, Nicolson T, Grunder S, Gomperts M, Clarke JD, Wilson SW.
Citation:
Neuron. 2003 Jul 31;39(3):423-38.
Epub:
Not Epub
Abstract:
The mechanisms that establish behavioral, cognitive, and neuroanatomical asymmetries are poorly understood. In this study, we...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Concha ML, Russell C, Regan JC, Tawk M, Sidi S, Gilmour DT, Kapsimali M, Sumoy L, Goldstone K, Amaya E, Kimelman D, Nicolson T, Grunder S, Gomperts M, Clarke JD, Wilson SW.. Local tissue interactions across the dorsal midline of the forebrain establish CNS laterality.. Neuron. 2003 Jul 31;39(3):423-38..

Loss of hspa9b in zebrafish recapitulates the ineffective hematopoiesis of the myelodysplastic syndromes

Authors:
Craven SE, French D, Ye W, de Sauvage F, Rosenthal A
Citation:
Blood. 2005 May 1;105(9):3528-34. Epub 2005 Jan 13.
Epub:
Not Epub
Abstract:
Myelodysplastic syndrome (MDS) comprises a heterogeneous group of often fatal hematopoietic stem cell disorders for which...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Craven SE, French D, Ye W, de Sauvage F, Rosenthal A. Loss of hspa9b in zebrafish recapitulates the ineffective hematopoiesis of the myelodysplastic syndromes. Blood. 2005 May 1;105(9):3528-34. Epub 2005 Jan 13..

Membrane wounding triggers ATP release and dysferlin-mediated intercellular calcium signaling

Authors:
Covian-Nares JF, Koushik SV, Puhl HL 3rd, Vogel SS
Citation:
J Cell Sci. 2010 May 4. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Dysferlin is a Ca(2+)-binding protein found in many different cell types. It is required for membrane wound repair in muscle,...
Organism or Cell Type:
sea urchin
Citation Extract:
Covian-Nares JF, Koushik SV, Puhl HL 3rd, Vogel SS. Membrane wounding triggers ATP release and dysferlin-mediated intercellular calcium signaling. J Cell Sci. 2010 May 4. [Epub ahead of print].

Membrane-type 1 matrix metalloproteinase regulates cell migration during zebrafish gastrulation: Evidence for an interaction with non-canonical Wnt signaling

Authors:
Coyle RC, Latimer A, Jessen JR
Citation:
Exp Cell Res. 2008 Jun 10;314(10):2150-62. Epub 2008 Mar 21.
Epub:
Not Epub
Abstract:
Key to invasiveness is the ability of tumor cells to modify the extracellular matrix, become motile, and engage in directed...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Coyle RC, Latimer A, Jessen JR. Membrane-type 1 matrix metalloproteinase regulates cell migration during zebrafish gastrulation: Evidence for an interaction with non-canonical Wnt signaling. Exp Cell Res. 2008 Jun 10;314(10):2150-62. Epub 2008 Mar 21..

miR-204 is required for lens and retinal development via Meis2 targeting

Authors:
Conte I, Carrella S, Avellino R, Karali M, Marco-Ferreres R, Bovolenta P, Banfi S
Citation:
Proc Natl Acad Sci U S A. 2010 Aug 16. [Epub ahead of print]
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) are small noncoding RNAs that have important roles in the regulation of gene expression. The roles of...
Delivery Method:
Microinjection
Organism or Cell Type:
medaka
Citation Extract:
Conte I, Carrella S, Avellino R, Karali M, Marco-Ferreres R, Bovolenta P, Banfi S. miR-204 is required for lens and retinal development via Meis2 targeting. Proc Natl Acad Sci U S A. 2010 Aug 16. [Epub ahead of print].

Mnx1: a gatekeeper of β cell fate

Authors:
Dalgin G, Prince VE
Citation:
Islets. 2012 Jul-Aug;4(4):320-2. doi: 10.4161/isl.21984. Epub 2012 Jul 1
Epub:
Not Epub
Abstract:
A full understanding of embryonic endocrine pancreas development will be key to the establishment of islet replacement...
Organism or Cell Type:
zebrafish
Citation Extract:
Dalgin G, Prince VE. Mnx1: a gatekeeper of β cell fate. Islets. 2012 Jul-Aug;4(4):320-2. doi: 10.4161/isl.21984. Epub 2012 Jul 1.

Morpholino antisense oligonucleotides: tools for investigating vertebrate development

Authors:
Corey DR, Abrams JM
Citation:
Genome Biology 2001 2(5): reviews1015.1-1015.3
Epub:
Not Epub
Abstract:
Antisense oligonucleotides provide a promising approach to investigating gene function in vivo, but their ability to offer...
Delivery Method:
not applicable
Organism or Cell Type:
not applicable
Citation Extract:
Corey DR, Abrams JM. Morpholino antisense oligonucleotides: tools for investigating vertebrate development. Genome Biology 2001 2(5): reviews1015.1-1015.3.

Negative regulation of Smad2 by PIASy is required for proper Xenopus mesoderm formation

Authors:
Daniels M, Shimizu K, Zorn AM, Ohnuma S
Citation:
Development. 2004 Nov;131(22):5613-26. Epub 2004 Oct 20
Epub:
Not Epub
Abstract:
Mesoderm induction and patterning are primarily regulated by the concentration of locally expressed morphogens such as members...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Daniels M, Shimizu K, Zorn AM, Ohnuma S. Negative regulation of Smad2 by PIASy is required for proper Xenopus mesoderm formation. Development. 2004 Nov;131(22):5613-26. Epub 2004 Oct 20.

Noggin1 and Follistatin-like2 function redundantly to Chordin to antagonize BMP activity

Authors:
Dal-Pra S, Fürthauer M, Van-Celst J, Thisse B, Thisse C
Citation:
Dev Biol. 2006 Oct 15;298(2):514-26. Epub 2006 Jul 12.
Epub:
Not Epub
Abstract:
In Xenopus, the dorso-ventral (D/V) axis is thought to be specified by the bone morphogenetic proteins (Bmp) activity arising...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Dal-Pra S, Fürthauer M, Van-Celst J, Thisse B, Thisse C. Noggin1 and Follistatin-like2 function redundantly to Chordin to antagonize BMP activity. Dev Biol. 2006 Oct 15;298(2):514-26. Epub 2006 Jul 12..

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