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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Molecular Mechanisms in Morpholino-DNA Surface Hybridization

Authors:
Gong P, Wang K, Liu Y, Shepard K, Levicky R
Citation:
J Am Chem Soc. 2010 Jun 24. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Synthetic nucleic acid mimics provide opportunity for redesigning the specificity and affinity of hybridization with natural...
Citation Extract:
Gong P, Wang K, Liu Y, Shepard K, Levicky R. Molecular Mechanisms in Morpholino-DNA Surface Hybridization. J Am Chem Soc. 2010 Jun 24. [Epub ahead of print].

NAD+ Biosynthesis Ameliorates a Zebrafish Model of Muscular Dystrophy

Authors:
Goody MF, Kelly MW, Reynolds CJ, Khalil A, Crawford BD, Henry CA
Citation:
PLoS Biol. 2012;10(10): e1001409. doi:10.1371/journal.pbio.1001409
Epub:
Not Epub
Abstract:
Muscular dystrophies are common, currently incurable diseases. A subset of dystrophies result from genetic disruptions in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Goody MF, Kelly MW, Reynolds CJ, Khalil A, Crawford BD, Henry CA. NAD+ Biosynthesis Ameliorates a Zebrafish Model of Muscular Dystrophy. PLoS Biol. 2012;10(10): e1001409. doi:10.1371/journal.pbio.1001409.

Nrk2b-mediated NAD+ production regulates cell adhesion and is required for muscle morphogenesis in vivo: Nrk2b and NAD+ in muscle morphogenesis

Authors:
Goody MF, Kelly MW, Lessard KN, Khalil A, Henry CA
Citation:
Dev Biol. 2010 Aug 15;344(2):809-26. Epub 2010 Jun 8
Epub:
Not Epub
Abstract:
Cell-matrix adhesion complexes (CMACs) play fundamental roles during morphogenesis. Given the ubiquitous nature of CMACs and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Goody MF, Kelly MW, Lessard KN, Khalil A, Henry CA. Nrk2b-mediated NAD+ production regulates cell adhesion and is required for muscle morphogenesis in vivo: Nrk2b and NAD+ in muscle morphogenesis. Dev Biol. 2010 Aug 15;344(2):809-26. Epub 2010 Jun 8.

OTUB1 modulates c-IAP1 stability to regulate signalling pathways

Authors:
Goncharov T, Niessen K, de Almagro MC, Izrael-Tomasevic A, Fedorova AV, Varfolomeev E, Arnott D, Deshayes K, Kirkpatrick DS, Vucic D
Citation:
EMBO J. 2013;[Epub ahead of print] doi:10.1038/emboj.2013.62
Epub:
Not Epub
Abstract:
The cellular inhibitor of apoptosis (c-IAP) proteins are E3 ubiquitin ligases that are critical regulators of tumour necrosis...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Goncharov T, Niessen K, de Almagro MC, Izrael-Tomasevic A, Fedorova AV, Varfolomeev E, Arnott D, Deshayes K, Kirkpatrick DS, Vucic D. OTUB1 modulates c-IAP1 stability to regulate signalling pathways. EMBO J. 2013;[Epub ahead of print] doi:10.1038/emboj.2013.62.

Plasma membrane Ca2+ ATPase Atp2b1a Regulates Bone Mineralisation in Zebrafish

Authors:
Go W, Korzh V
Citation:
Bone. 2013 Jan 24. doi:pii: S8756-3282(13)00043-4. 10.1016/j.bone.2013.01.026. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The zebrafish transgenic lines provide a possibility to observe development of tissues and organs in real time. Using the...
Organism or Cell Type:
zebrafish
Citation Extract:
Go W, Korzh V. Plasma membrane Ca2+ ATPase Atp2b1a Regulates Bone Mineralisation in Zebrafish. Bone. 2013 Jan 24. doi:pii: S8756-3282(13)00043-4. 10.1016/j.bone.2013.01.026. [Epub ahead of print].

Poly(A)-binding proteins are functionally distinct and have essential roles during vertebrate development

Authors:
Gorgoni B, Richardson WA, Burgess HM, Anderson RC, Wilkie GS, Gautier P, Sousa Martins JP, Brook M, Sheets MD, Gray NK
Citation:
Proc Natl Acad Sci U S A. 2011;[Epub ahead of print] 10.1073/pnas.1017664108
Epub:
Not Epub
Abstract:
Translational control of many mRNAs in developing metazoan embryos is achieved by alterations in their poly(A) tail length. A...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gorgoni B, Richardson WA, Burgess HM, Anderson RC, Wilkie GS, Gautier P, Sousa Martins JP, Brook M, Sheets MD, Gray NK. Poly(A)-binding proteins are functionally distinct and have essential roles during vertebrate development. Proc Natl Acad Sci U S A. 2011;[Epub ahead of print] 10.1073/pnas.1017664108.

Prevention of Dystrophic Pathology in Severely Affected Dystrophin/Utrophin-deficient Mice by Morpholino-oligomer-mediated Exon-skipping

Authors:
Goyenvalle A, Babbs A, Powell D, Kole R, Fletcher S, Wilton SD, Davies KE
Citation:
Mol Ther. 2009 Oct 20. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is a severe neuromuscular disorder caused by mutations in the dystrophin gene that result in...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice: dystrophin & utrophin dKO
Citation Extract:
Goyenvalle A, Babbs A, Powell D, Kole R, Fletcher S, Wilton SD, Davies KE. Prevention of Dystrophic Pathology in Severely Affected Dystrophin/Utrophin-deficient Mice by Morpholino-oligomer-mediated Exon-skipping. Mol Ther. 2009 Oct 20. [Epub ahead of print].

Rspo1/Wnt signaling promotes angiogenesis via Vegfc/Vegfr3

Authors:
Gore AV, Swift MR, Cha YR, Lo B, McKinney MC, Li W, Castranova D, Davis A, Mukouyama YS, Weinstein BM
Citation:
Development. 2011 Oct 17. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Here, we show that a novel Rspo1-Wnt-Vegfc-Vegfr3 signaling pathway plays an essential role in developmental angiogenesis. A...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gore AV, Swift MR, Cha YR, Lo B, McKinney MC, Li W, Castranova D, Davis A, Mukouyama YS, Weinstein BM. Rspo1/Wnt signaling promotes angiogenesis via Vegfc/Vegfr3. Development. 2011 Oct 17. [Epub ahead of print].

TBX5 is required for embryonic cardiac cell cycle progression

Authors:
Goetz SC, Brown DD, Conlon FL
Citation:
Development. 2006 Jul;133(13):2575-84. Epub 2006 May 25
Epub:
Not Epub
Abstract:
Despite the critical importance of TBX5 in normal development and disease, relatively little is known about the mechanisms by...
Organism or Cell Type:
Xenopus
Citation Extract:
Goetz SC, Brown DD, Conlon FL. TBX5 is required for embryonic cardiac cell cycle progression. Development. 2006 Jul;133(13):2575-84. Epub 2006 May 25.

The heparan sulfate editing enzyme Sulf1 plays a novel role in zebrafish VegfA mediated arterial venous identity

Authors:
Gorsi B, Liu F, Ma X, Chico TJA, Shrinivasan A, Kramer KL, Bridges E, Monteiro R, Harris AL, Patient R, Stringer SE
Citation:
Angiogenesis. 2013;[Epub ahead of print] doi:10.1007/s10456-013-9379-0
Epub:
Not Epub
Abstract:
Arterial and venous specification is critical for establishing and maintaining a functioning vascular system, and defects in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gorsi B, Liu F, Ma X, Chico TJA, Shrinivasan A, Kramer KL, Bridges E, Monteiro R, Harris AL, Patient R, Stringer SE. The heparan sulfate editing enzyme Sulf1 plays a novel role in zebrafish VegfA mediated arterial venous identity. Angiogenesis. 2013;[Epub ahead of print] doi:10.1007/s10456-013-9379-0.

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