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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Paralysis and delayed Z-disc formation in the Xenopus tropicalis unc45b mutant dicky ticker

Authors:
Geach TJ, Zimmerman LB
Citation:
BMC Dev Biol. 2010 Jul 16;10(1):75. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The protein components of mature skeletal muscle have largely been characterized, but the mechanics and sequence of their...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Geach TJ, Zimmerman LB. Paralysis and delayed Z-disc formation in the Xenopus tropicalis unc45b mutant dicky ticker. BMC Dev Biol. 2010 Jul 16;10(1):75. [Epub ahead of print].

Perlecan-Induced Suppression of Smooth Muscle Cell Proliferation Is Mediated Through Increased Activity of the Tumor Suppressor PTEN

Authors:
Garl PJ, Wenzlau JM, Walker HA, Whitelock JM, Costell M, Weiser-Evans MC
Citation:
Circ Res. 2004 Feb 6;94(2):175-83.
Epub:
Not Epub
Abstract:
We were interested in the elucidation of the interaction between the heparan sulfate proteoglycan, perlecan, and PTEN in the...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: vascular smooth muscle cells
Citation Extract:
Garl PJ, Wenzlau JM, Walker HA, Whitelock JM, Costell M, Weiser-Evans MC. Perlecan-Induced Suppression of Smooth Muscle Cell Proliferation Is Mediated Through Increased Activity of the Tumor Suppressor PTEN. Circ Res. 2004 Feb 6;94(2):175-83..

Physical Interaction Between Tbx5 and Mef2c is Required for Early Heart Development

Authors:
Ghosh TK, Song FF, Packham EA, Buxton S, Robinson TE, Ronksley J, Self T, Bonser AJ, Brook JD
Citation:
Mol Cell Biol. 2009 Feb 9. [Epub ahead of print]
Epub:
Not Epub
Abstract:
TBX5 is a transcription factor which plays important roles in the development of the heart and upper-limbs. Mutations in this...
Organism or Cell Type:
zebrafish
Citation Extract:
Ghosh TK, Song FF, Packham EA, Buxton S, Robinson TE, Ronksley J, Self T, Bonser AJ, Brook JD. Physical Interaction Between Tbx5 and Mef2c is Required for Early Heart Development. Mol Cell Biol. 2009 Feb 9. [Epub ahead of print].

Pro-metastatic splicing of Ron proto-oncogene mRNA can be reversed: therapeutic potential of bifunctional oligonucleotides and indole derivatives

Authors:
Ghigna C, De Toledo M, Bonomi S, Valacca C, Gallo S, Apicella M, Eperon I, Tazi J, Biamonti G
Citation:
RNA Biol. 2010 Jul-Aug;7(4):495-503. Epub 2010 Jul 1
Epub:
Not Epub
Abstract:
Alternative splicing is a key molecular mechanism for increasing the complexity of the human transcriptome. Nearly all human...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture, human various
Citation Extract:
Ghigna C, De Toledo M, Bonomi S, Valacca C, Gallo S, Apicella M, Eperon I, Tazi J, Biamonti G. Pro-metastatic splicing of Ron proto-oncogene mRNA can be reversed: therapeutic potential of bifunctional oligonucleotides and indole derivatives. RNA Biol. 2010 Jul-Aug;7(4):495-503. Epub 2010 Jul 1.

Prolactin receptor knockdown in the rat paraventricular nucleus by a morpholino-antisense oligonucleotide causes hypocalcemia and stress gastric erosion

Authors:
Fujikawa T, Tamura K, Kawase T, Mori Y, Sakai RR, Sakuma K, Yamaguchi A, Ogata M, Soya H, Nakashima K.
Citation:
Endocrinology. 2005 Aug;146(8):3471-80. Epub 2005 Apr 21.
Epub:
Not Epub
Abstract:
Under acute stress conditions in the rat, there is rapid and transient increase in circulating prolactin (PRL). This leads to...
Delivery Method:
in vivo: injection
Organism or Cell Type:
rats, Sprague Dawley
Citation Extract:
Fujikawa T, Tamura K, Kawase T, Mori Y, Sakai RR, Sakuma K, Yamaguchi A, Ogata M, Soya H, Nakashima K.. Prolactin receptor knockdown in the rat paraventricular nucleus by a morpholino-antisense oligonucleotide causes hypocalcemia and stress gastric erosion. Endocrinology. 2005 Aug;146(8):3471-80. Epub 2005 Apr 21..

Rargb regulates organ laterality in a zebrafish model of right atrial isomerism

Authors:
Garnaas MK, Cutting CC, Meyers A, Kelsey PB Jr, Harris JM, North TE, Goessling W
Citation:
Dev Biol. 2012 Sep 13. pii: S0012-1606(12)00492-7. doi: 10.1016/j.ydbio.2012.09.001. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Developmental signals determine organ morphology and position during embryogenesis. To discover novel modifiers of liver...
Organism or Cell Type:
zebrafish
Citation Extract:
Garnaas MK, Cutting CC, Meyers A, Kelsey PB Jr, Harris JM, North TE, Goessling W. Rargb regulates organ laterality in a zebrafish model of right atrial isomerism. Dev Biol. 2012 Sep 13. pii: S0012-1606(12)00492-7. doi: 10.1016/j.ydbio.2012.09.001. [Epub ahead of print].

Rbfox-regulated alternative splicing is critical for zebrafish cardiac and skeletal muscle functions

Authors:
Gallagher TL, Arribere JA, Geurts PA, Exner CR, McDonald KL, Dill KK, Marr HL, Adkar SS, Garnett AT, Amacher SL, Conboy JG
Citation:
Dev Biol. 2011 Sep 7. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Rbfox RNA binding proteins are implicated as regulators of phylogenetically-conserved alternative splicing events important for...
Organism or Cell Type:
zebrafish
Citation Extract:
Gallagher TL, Arribere JA, Geurts PA, Exner CR, McDonald KL, Dill KK, Marr HL, Adkar SS, Garnett AT, Amacher SL, Conboy JG. Rbfox-regulated alternative splicing is critical for zebrafish cardiac and skeletal muscle functions. Dev Biol. 2011 Sep 7. [Epub ahead of print].

Reduced TFAP2A function causes variable optic fissure closure and retinal defects and sensitizes eye development to mutations in other morphogenetic regulators

Authors:
Gestri G, Osborne RJ, Wyatt AW, Gerrelli D, Gribble S, Stewart H, Fryer A, Bunyan DJ, Prescott K, Collin JR, Fitzgerald T, Robinson D, Carter NP, Wilson SW, Ragge NK
Citation:
Hum Genet. 2009 Aug 14. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Mutations in the transcription factor encoding TFAP2A gene underlie branchio-oculo-facial syndrome (BOFS), a rare dominant...
Organism or Cell Type:
zebrafish
Citation Extract:
Gestri G, Osborne RJ, Wyatt AW, Gerrelli D, Gribble S, Stewart H, Fryer A, Bunyan DJ, Prescott K, Collin JR, Fitzgerald T, Robinson D, Carter NP, Wilson SW, Ragge NK. Reduced TFAP2A function causes variable optic fissure closure and retinal defects and sensitizes eye development to mutations in other morphogenetic regulators. Hum Genet. 2009 Aug 14. [Epub ahead of print].

Reexpression of pyruvate kinase M2 in type 1 myofibers correlates with altered glucose metabolism in myotonic dystrophy

Authors:
Gao Z, Cooper TA
Citation:
PNAS USA. 2013; [Epub ahead of print] doi:10.1073/pnas.1308806110
Epub:
Not Epub
Abstract:
Myotonic dystrophy type 1 (DM1) is caused by expansion of CTG repeats in the 3′ UTR of the DMPK gene. Expression of CUG...
Organism or Cell Type:
mice and cell culture
Citation Extract:
Gao Z, Cooper TA. Reexpression of pyruvate kinase M2 in type 1 myofibers correlates with altered glucose metabolism in myotonic dystrophy. PNAS USA. 2013; [Epub ahead of print] doi:10.1073/pnas.1308806110 .

Regulation of ciliary polarity by the APC/C

Authors:
Ganner A, Lienkamp S, Schäfer T, Romaker D, Wegierski T, Park TJ, Spreitzer S, Simons M, Gloy J, Kim E, Wallingford JB, Walz G
Citation:
Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17799-804. Epub 2009 Oct 5
Epub:
Not Epub
Abstract:
Planar cell polarity signaling controls a variety of polarized cell behaviors. In multiciliated Xenopus epidermal cells,...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ganner A, Lienkamp S, Schäfer T, Romaker D, Wegierski T, Park TJ, Spreitzer S, Simons M, Gloy J, Kim E, Wallingford JB, Walz G. Regulation of ciliary polarity by the APC/C. Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17799-804. Epub 2009 Oct 5.

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