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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Generation and Characterization of a zebrafish model of SMA carrying the human SMN2 gene
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Citation:
Molecular Neurodegeneration 2011, 6:24 doi:10.1186/1750-1326-6-24 Epub:
Not Epub Abstract:
Animal models of human diseases are essential as they allow analysis of the disease process at the cellular level and can... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Hao LT, Burghes AHM, Beattie CE. Generation and Characterization of a zebrafish model of SMA carrying the human SMN2 gene. Molecular Neurodegeneration 2011, 6:24 doi:10.1186/1750-1326-6-24. |
Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during kidney development
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Citation:
Development. 2010 Apr;137(7):1189-203 Epub:
Not Epub Abstract:
The Wilms' tumor suppressor 1 (WT1) gene encodes a DNA- and RNA-binding protein that plays an essential role in nephron... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Mouse kidney explants, embryonic Citation Extract: Hartwig S, Ho J, Pandey P, Macisaac K, Taglienti M, Xiang M, Alterovitz G, Ramoni M, Fraenkel E, Kreidberg JA. Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during kidney development. Development. 2010 Apr;137(7):1189-203. |
Glucose metabolism impacts the spatio-temporal onset and magnitude of HSC induction in vivo
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Citation:
Blood. 2012;[Epub ahead of print] doi:10.1182/blood-2012-12-471201 Epub:
Not Epub Abstract:
Many pathways regulating blood formation have been elucidated, yet how each coordinates with embryonic biophysiology to... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Harris JM, Esain V, Frechette GM, Harris LJ, Cox AG, Cortes M, Garnaas MK, Carroll KJ, Cutting CC, Khan T, Elks PM, Renshaw SA, Dickinson BC, Chang CJ, Murphy MP, Paw BH, Heiden MGV, Goessling W, North TE. Glucose metabolism impacts the spatio-temporal onset and magnitude of HSC induction in vivo. Blood. 2012;[Epub ahead of print] doi:10.1182/blood-2012-12-471201. |
Glycome and transcriptome regulation of vasculogenesis
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Citation:
Circulation. 2009 Nov 10;120(19):1883-92. Epub 2009 Oct 26 Epub:
Not Epub Abstract:
BACKGROUND: Therapeutic vasculogenesis is an emerging concept that can potentially be harnessed for the management of ischemic... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Harfouche R, Hentschel DM, Piecewicz S, Basu S, Print C, Eavarone D, Kiziltepe T, Sasisekharan R, Sengupta S. Glycome and transcriptome regulation of vasculogenesis. Circulation. 2009 Nov 10;120(19):1883-92. Epub 2009 Oct 26. |
her3, a zebrafish member of the hairy-E(spl) family, is repressed by Notch signalling
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Citation:
Development. 2004 Jun;131(12):2957-2969 Epub:
Not Epub Abstract:
her3 encodes a zebrafish bHLH protein of the Hairy-E(Spl) family. During embryogenesis, the gene is transcribed exclusively in... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Hans S, Scheer N, Riedl I, Weizsäcker E, Blader P, Campos-Ortega JA. her3, a zebrafish member of the hairy-E(spl) family, is repressed by Notch signalling. Development. 2004 Jun;131(12):2957-2969. |
How Variable Clones Build an Invariant Retina
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Citation:
Neuron. 2012;75(5):786-798. doi:10.1016/j.neuron.2012.06.033 Epub:
Not Epub Abstract:
A fundamental question in developmental neuroscience is how a collection of progenitor cells proliferates and differentiates to... Organism or Cell Type:
zebrafish Citation Extract: He J, Zhang G, Almeida AD, Cayouette M, Simons BD, Harris WA. How Variable Clones Build an Invariant Retina. Neuron. 2012;75(5):786-798. doi:10.1016/j.neuron.2012.06.033. |
In vivo comparison of 2'-O-methyl phosphorothioate and morpholino antisense oligonucleotides for Duchenne muscular dystrophy exon skipping
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Citation:
J Gene Med. 2009 Mar;11(3):257-66. doi: 10.1002/jgm.1288 Epub:
Not Epub Abstract:
BACKGROUND: Antisense-mediated exon skipping is a putative treatment for Duchenne muscular dystrophy (DMD). Using antisense... Delivery Method:
i.m. injection Organism or Cell Type:
mice Citation Extract: Heemskerk HA, de Winter CL, de Kimpe SJ, van Kuik-Romeijn P, Heuvelmans N, Platenburg GJ, van Ommen GJ, van Deutekom JC, Aartsma-Rus A. In vivo comparison of 2'-O-methyl phosphorothioate and morpholino antisense oligonucleotides for Duchenne muscular dystrophy exon skipping. J Gene Med. 2009 Mar;11(3):257-66. doi: 10.1002/jgm.1288. |
In vivo studies of liver-type fatty acid binding protein (L-FABP) gene expression in liver of transgenic zebrafish (Danio rerio).
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Citation:
FEBS Lett 2003 Mar 13;538(1-3):125-33 Epub:
Not Epub Abstract:
Mammalian liver fatty acid binding protein (L-FABP) is a small cytosolic protein in various tissues including liver, small... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Her GM, Chiang CC, Chen WY, Wu JL. In vivo studies of liver-type fatty acid binding protein (L-FABP) gene expression in liver of transgenic zebrafish (Danio rerio).. FEBS Lett 2003 Mar 13;538(1-3):125-33. |
Initiation of zebrafish haematopoiesis by the TATA-box-binding protein-related factor Trf3
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Citation:
Nature. 2007 Dec 13;450(7172):1082-5. Epub 2007 Nov 28 Epub:
Not Epub Abstract:
TATA-box-binding protein (TBP)-related factor 3, TRF3 (also called TBP2), is a vertebrate-specific member of the TBP family... Organism or Cell Type:
zebrafish Citation Extract: Hart DO, Raha T, Lawson ND, Green MR. Initiation of zebrafish haematopoiesis by the TATA-box-binding protein-related factor Trf3. Nature. 2007 Dec 13;450(7172):1082-5. Epub 2007 Nov 28. |
Innate immune response to Streptococcus iniae infection in zebrafish larvae
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Citation:
Infect Immun. 2013 Jan;81(1):110-21. doi: 10.1128/IAI.00642-12. Epub 2012 Oct 22 Epub:
Not Epub Abstract:
Streptococcus iniae causes systemic infection characterized by meningitis and sepsis. Here, we report a larval zebrafish model... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Harvie EA, Green JM, Neely MN, Huttenlocher A. Innate immune response to Streptococcus iniae infection in zebrafish larvae. Infect Immun. 2013 Jan;81(1):110-21. doi: 10.1128/IAI.00642-12. Epub 2012 Oct 22. |