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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

A mutation in the Gsk3-binding domain of zebrafish Masterblind/Axin1 leads to a fate transformation of telencephalon and eyes to diencephalon

Authors:
Heisenberg CP, Houart C, Take-Uchi M, Rauch GJ, Young N, Coutinho P, Masai I, Caneparo L, Concha ML, Geisler R, Dale TC, Wilson SW, Stemple DL
Citation:
Genes Dev. 2001 Jun 1;15(11):1427-34
Epub:
Not Epub
Abstract:
Zebrafish embryos homozygous for the masterblind (mbl) mutation exhibit a striking phenotype in which the eyes and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Heisenberg CP, Houart C, Take-Uchi M, Rauch GJ, Young N, Coutinho P, Masai I, Caneparo L, Concha ML, Geisler R, Dale TC, Wilson SW, Stemple DL. A mutation in the Gsk3-binding domain of zebrafish Masterblind/Axin1 leads to a fate transformation of telencephalon and eyes to diencephalon. Genes Dev. 2001 Jun 1;15(11):1427-34.

A role for Tbx5 in proepicardial cell migration during cardiogenesis

Authors:
Hatcher CJ, Diman NY, Kim MS, Pennisi D, Song Y, Goldstein MM, Mikawa T, Basson CT
Citation:
Physiol Genomics. 2004 Jul 8;18(2):129-40
Epub:
Not Epub
Abstract:
Transcriptional regulatory cascades during epicardial and coronary vascular development from proepicardial progenitor cells...
Delivery Method:
Special Delivery
Organism or Cell Type:
organ culture: chick proepicardial organ explant
Citation Extract:
Hatcher CJ, Diman NY, Kim MS, Pennisi D, Song Y, Goldstein MM, Mikawa T, Basson CT. A role for Tbx5 in proepicardial cell migration during cardiogenesis. Physiol Genomics. 2004 Jul 8;18(2):129-40.

A sensitive and reproducible assay to measure the activity of glucosylceramide synthase and lactosylceramide synthase using HPLC and fluorescent substrates

Authors:
Hayashi Y, Horibata Y, Sakaguchi K, Okino N, Ito M
Citation:
Anal Biochem. 2005 Oct 15;345(2):181-6. Epub 2005 Jun 13.
Epub:
Not Epub
Abstract:
Glucosylceramide synthase (GlcT) and lactosylceramide synthase (GalT) are key enzymes for the synthesis of major...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hayashi Y, Horibata Y, Sakaguchi K, Okino N, Ito M. A sensitive and reproducible assay to measure the activity of glucosylceramide synthase and lactosylceramide synthase using HPLC and fluorescent substrates. Anal Biochem. 2005 Oct 15;345(2):181-6. Epub 2005 Jun 13..

A Y-linked anti-Mullerian hormone duplication takes over a critical role in sex determination

Authors:
Hattori RS, Murai Y, Oura M, Masuda S, Majhi SK, Sakamoto T, Fernandino JI, Somoza GM, Yokota M, Strüssmann CA
Citation:
Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2955-9. Epub 2012 Feb 7
Epub:
Not Epub
Abstract:
Gonadal sex determination in vertebrates generally follows a sequence of genetically programmed events. In what is seemingly...
Delivery Method:
Microinjection
Organism or Cell Type:
Odontesthes hatcheri (Patagonian pejerrey)
Citation Extract:
Hattori RS, Murai Y, Oura M, Masuda S, Majhi SK, Sakamoto T, Fernandino JI, Somoza GM, Yokota M, Strüssmann CA. A Y-linked anti-Mullerian hormone duplication takes over a critical role in sex determination. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2955-9. Epub 2012 Feb 7.

Affinity enhancement bivalent morpholino for pretargeting: initial evidence by surface plasmon resonance

Authors:
He J, Liu G, Vanderheyden JL, Dou S, Mary R, Hnatowich DJ
Citation:
Bioconjug Chem. 2005 Mar-Apr;16(2):338-45
Epub:
Not Epub
Abstract:
Pretargeting with bivalent effectors capable of bridging antitumor antibodies has been reported to provide superior results by...
Delivery Method:
not applicable
Organism or Cell Type:
not applicable
Citation Extract:
He J, Liu G, Vanderheyden JL, Dou S, Mary R, Hnatowich DJ. Affinity enhancement bivalent morpholino for pretargeting: initial evidence by surface plasmon resonance. Bioconjug Chem. 2005 Mar-Apr;16(2):338-45.

Affinity enhancement bivalent morpholinos for pretargeting: surface plasmon resonance studies of molecular dimensions

Authors:
He J, Liu X, Zhang S, Liu G, Hnatowich DJ
Citation:
Bioconjug Chem. 2005 Sep-Oct;16(5):1098-104
Epub:
Not Epub
Abstract:
Bivalent effectors have been reported to provide superior pretargeting by affinity enhancement. We recently reported that one...
Delivery Method:
not applicable
Organism or Cell Type:
Abiotic system
Citation Extract:
He J, Liu X, Zhang S, Liu G, Hnatowich DJ. Affinity enhancement bivalent morpholinos for pretargeting: surface plasmon resonance studies of molecular dimensions. Bioconjug Chem. 2005 Sep-Oct;16(5):1098-104.

Affinity Enhancement Pretargeting: synthesis and testing of a 99mTc-labeled bivalent MORF

Authors:
He J, Wang Y, Dou S, Liu X, Zhang S, Liu G, Hnatowich D
Citation:
Mol Pharm. 2010 Aug 2;7(4):1118-24. doi: 10.1021/mp9002909
Epub:
Not Epub
Abstract:
Pretargeting with bivalent effectors capable of bridging antitumor antibodies (affinity enhancement pretargeting) has been...
Link:
http://pubs.acs.org/doi/abs/10.1021/mp9002909
Organism or Cell Type:
mice and cell culture
Citation Extract:
He J, Wang Y, Dou S, Liu X, Zhang S, Liu G, Hnatowich D. Affinity Enhancement Pretargeting: synthesis and testing of a 99mTc-labeled bivalent MORF. Mol Pharm. 2010 Aug 2;7(4):1118-24. doi: 10.1021/mp9002909.

Amplification targeting: a modified pretargeting approach with potential for signal amplification-proof of a concept

Authors:
He J, Liu G, Gupta S, Zhang Y, Rusckowski M, Hnatowich DJ
Citation:
J Nucl Med. 2004 Jun;45(6):1087-95
Epub:
Not Epub
Abstract:
Conventional nuclear medicine imaging with large radiolabeled molecules such as antitumor antibodies suffers from slow...
Organism or Cell Type:
mice, nude
Citation Extract:
He J, Liu G, Gupta S, Zhang Y, Rusckowski M, Hnatowich DJ. Amplification targeting: a modified pretargeting approach with potential for signal amplification-proof of a concept. J Nucl Med. 2004 Jun;45(6):1087-95.

An Improved Method for Covalently Conjugating Morpholino Oligomers to Antitumor Antibodies

Authors:
He J, Liu G, Dou S, Gupta S, Rusckowski M, Hnatowich D
Citation:
Bioconjug Chem. 2007 May-Jun;18(3):983-8. Epub 2007 Mar 27.
Epub:
Not Epub
Abstract:
Whether for conventional pretargeting, amplification pretargeting, or affinity enhancement pretargeting, it will be necessary...
Citation Extract:
He J, Liu G, Dou S, Gupta S, Rusckowski M, Hnatowich D. An Improved Method for Covalently Conjugating Morpholino Oligomers to Antitumor Antibodies. Bioconjug Chem. 2007 May-Jun;18(3):983-8. Epub 2007 Mar 27..

Analysis of leukemia inhibitory factor and leukemia inhibitory factor receptor in embryonic and adult zebrafish (Danio rerio)

Authors:
Hanington PC, Patten SA, Reaume LM, Waskiewicz AJ, Belosevic M, Ali DW
Citation:
Dev Biol. 2008 Feb 15;314(2):250-60. Epub 2007 Oct 22.
Epub:
Not Epub
Abstract:
Leukemia inhibitory factor (LIF) is a member of the IL-6 cytokine family that functions in the survival, repair and formation...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hanington PC, Patten SA, Reaume LM, Waskiewicz AJ, Belosevic M, Ali DW. Analysis of leukemia inhibitory factor and leukemia inhibitory factor receptor in embryonic and adult zebrafish (Danio rerio). Dev Biol. 2008 Feb 15;314(2):250-60. Epub 2007 Oct 22..

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