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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Engrailed and Fgf8 act synergistically to maintain the boundary between diencephalon and mesencephalon
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Citation:
Development. 2003 Oct;130(20):4881-93. doi: 10.1242/dev.00683. Epub 2003 Aug 13 Epub:
Not Epub Abstract:
Specification of the forebrain, midbrain and hindbrain primordia occurs during gastrulation in response to signals that pattern... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Scholpp S, Lohs C, Brand M. Engrailed and Fgf8 act synergistically to maintain the boundary between diencephalon and mesencephalon. Development. 2003 Oct;130(20):4881-93. doi: 10.1242/dev.00683. Epub 2003 Aug 13. |
SAT066 Leukotriene B4 Receptor 2 Mediates Macrophage Migration To Injured β Cells
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Citation:
J Endocrinol 2023;7(Supp1):bvad114.933. doi:10.1210/jendso/bvad114.933 Epub:
Not Epub Abstract:
Type 1 diabetes (T1D) is an autoimmune disease, characterized in part by islet inflammation and macrophage infiltration leading... Organism or Cell Type:
zebrafish Citation Extract: Ermis E, Nargis T, Kulkarni A, May S, Tersey SA, Mirmira RG, Anderson RM. SAT066 Leukotriene B4 Receptor 2 Mediates Macrophage Migration To Injured β Cells. J Endocrinol 2023;7(Supp1):bvad114.933. doi:10.1210/jendso/bvad114.933. |
The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling
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Citation:
Nat Commun. 2023 Oct 5;14(1):6173. doi: 10.1038/s41467-023-41836-z Epub:
Not Epub Abstract:
The relative abundance of Wnt receptors plays a crucial role in controlling Wnt signaling in tissue homeostasis and human... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, Li J, D'Souza S, Lebensohn AM, Rohatgi R, Weiss WA, Weiss VL, Williams C, Hong CC, Robbins DJ, Ahmed Y, Lee E. The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling. Nat Commun. 2023 Oct 5;14(1):6173. doi: 10.1038/s41467-023-41836-z. |
Xenopus Ssbp2 is required for embryonic pronephros morphogenesis and terminal differentiation
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Citation:
Sci Rep. 2023 Oct 4;13(1):16671. doi: 10.1038/s41598-023-43662-1 Epub:
Not Epub Abstract:
The nephron, functional unit of the vertebrate kidney, is specialized in metabolic wastes excretion and body fluids... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Cervino AS, Collodel MG, Lopez IA, Roa C, Hochbaum D, Hukriede NA, Cirio MC. Xenopus Ssbp2 is required for embryonic pronephros morphogenesis and terminal differentiation. Sci Rep. 2023 Oct 4;13(1):16671. doi: 10.1038/s41598-023-43662-1. |
Purine Biosynthesis Pathways Are Required for Myogenesis in Xenopus laevis
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Citation:
Cells. 2023;12:2379. doi:10.3390/cells12192379 Epub:
Not Epub Abstract:
Purines are required for fundamental biological processes and alterations in their metabolism lead to severe genetic diseases... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Duperray M, Hardet F, Henriet E, Saint-Marc C, Boué-Grabot E, Daignan-Fornier B, Massé K, Pinson B. Purine Biosynthesis Pathways Are Required for Myogenesis in Xenopus laevis. Cells. 2023;12:2379. doi:10.3390/cells12192379 . |
A digital twin reproducing gene regulatory network dynamics of early Ciona embryos indicates robust buffers in the network
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Citation:
PLoS Genet. 2023 Sep 27;19(9):e1010953. doi: 10.1371/journal.pgen.1010953. eCollection 2023 Sep Epub:
Not Epub Abstract:
How gene regulatory networks (GRNs) encode gene expression dynamics and how GRNs evolve are not well understood, although these... Delivery Method:
microinjection Organism or Cell Type:
Ciona intestinalis (ascidian) Citation Extract: Tokuoka M, Satou Y. A digital twin reproducing gene regulatory network dynamics of early Ciona embryos indicates robust buffers in the network. PLoS Genet. 2023 Sep 27;19(9):e1010953. doi: 10.1371/journal.pgen.1010953. eCollection 2023 Sep. |
Prickle and Ror modulate Dishevelled-Vangl interaction to regulate non-canonical Wnt signaling during convergent extension
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Citation:
eLife. 2023;12:RP91199 doi:10.7554/eLife.91199.1 Epub:
Not Epub Abstract:
Convergent extension (CE) is a fundamental morphogenetic process where oriented cell behaviors lead to polarized extension of... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Seo H-s, Yu D, Popov I, Tao J, Angermeier A, Sha B, Axelrod J, Chang C, Wang J. Prickle and Ror modulate Dishevelled-Vangl interaction to regulate non-canonical Wnt signaling during convergent extension. eLife. 2023;12:RP91199 doi:10.7554/eLife.91199.1. |
A bioelectrical phase transition patterns the first vertebrate heartbeats
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Citation:
Nature. 2023 Sep 27. doi: 10.1038/s41586-023-06561-z. Online ahead of print Epub:
Yes Abstract:
A regular heartbeat is essential to vertebrate life. In the mature heart, this function is driven by an anatomically localized... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jia BZ, Qi Y, Wong-Campos JD, Megason SG, Cohen AE. A bioelectrical phase transition patterns the first vertebrate heartbeats. Nature. 2023 Sep 27. doi: 10.1038/s41586-023-06561-z. Online ahead of print. |
Lymphatic Defects in Zebrafish sox18 Mutants Are Exacerbated by Perturbed VEGFC Signaling, While Masked by Elevated sox7 Expression
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Citation:
Cells. 2023 Sep 19;12(18):2309. doi: 10.3390/cells12182309 Epub:
Not Epub Abstract:
Mutations in the transcription factor-coding gene SOX18, the growth factor-coding gene VEGFC and its receptor-coding gene... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Moleri S, Mercurio S, Pezzotta A, D'Angelo D, Brix A, Plebani A, Lini G, Di Fuorti M, Beltrame M. Lymphatic Defects in Zebrafish sox18 Mutants Are Exacerbated by Perturbed VEGFC Signaling, While Masked by Elevated sox7 Expression. Cells. 2023 Sep 19;12(18):2309. doi: 10.3390/cells12182309. |
Regulation of Human Sortilin Alternative Splicing by Glucagon-like Peptide-1 (GLP1) in Adipocytes
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Citation:
Int J Mol Sci. 2023 Sep 20;24(18):14324. doi: 10.3390/ijms241814324 Epub:
Not Epub Abstract:
Type 2 diabetes mellitus is a chronic metabolic disease with no cure. Adipose tissue is a major site of systemic insulin... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: human diabetic pre-adipocytes Citation Extract: Lui A, Patel RS, Krause-Hauch M, Sparks RP, Patel NA. Regulation of Human Sortilin Alternative Splicing by Glucagon-like Peptide-1 (GLP1) in Adipocytes. Int J Mol Sci. 2023 Sep 20;24(18):14324. doi: 10.3390/ijms241814324. |