You are here
Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Peripheral blood transcriptome profiling enables monitoring disease progression in dystrophic mice and patients
|
Citation:
EMBO Mol Med. 2021;e13328. doi:10.15252/emmm.202013328 Epub:
Not Epub Abstract:
DMD is a rare disorder characterized by progressive muscle degeneration and premature death. Therapy development is delayed by... Delivery Method:
i.v. injection Organism or Cell Type:
mice mdx Citation Extract: Signorelli M, Ebrahimpoor M, Veth O, Hettne K, Verwey N, García‐Rodríguez R, Tanganyika‐deWinter CL, Lopez Hernandez LB, Cedillo RE, Díaz BG, Magnusson OT, Mei H, Tsonaka R, Aartsma‐Rus A, Spitali P. Peripheral blood transcriptome profiling enables monitoring disease progression in dystrophic mice and patients. EMBO Mol Med. 2021;e13328. doi:10.15252/emmm.202013328. |
Exome sequencing and functional studies in zebrafish identify WDR8 as the causative gene for isolated Microspherophakia in Indian families
|
Citation:
Hum Mol Genet. 2021;ddab061. doi:10.1093/hmg/ddab061 Epub:
Not Epub Abstract:
Isolated Microspherophakia (MSP) is an autosomal recessive disorder characterised by a smaller than normal spherical lens. Till... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Madhangi M, Dutta D, Show S, Bhat VK, Rather MI, Tiwari A, Singh N, Duvvari MR, Murthy GJ, Kumar A, Nongthomba U. Exome sequencing and functional studies in zebrafish identify WDR8 as the causative gene for isolated Microspherophakia in Indian families. Hum Mol Genet. 2021;ddab061. doi:10.1093/hmg/ddab061. |
An early global role for Axin is required for correct patterning of the anterior-posterior axis in the sea urchin embryo
|
Citation:
Development. 2021;dev.191197 doi:10.1242/dev.191197 Epub:
Yes Abstract:
Activation of Wnt/β-catenin (cWnt) signaling at the future posterior end of early bilaterian embryos is a highly conserved... Delivery Method:
microinjection Organism or Cell Type:
Strongylocentrotus purpuratus & Lytechinus variegatus (sea urchin) Citation Extract: Sun H, Peng CFJ, Wang L, Feng H, Wikramanayake AH
. An early global role for Axin is required for correct patterning of the anterior-posterior axis in the sea urchin embryo. Development. 2021;dev.191197 doi:10.1242/dev.191197. |
Characterization of quinoxaline derivatives for protection against iatrogenically induced hearing loss
|
Citation:
JCI Insight. 2021 Mar 8;6(5):141561. doi: 10.1172/jci.insight.141561 Epub:
Not Epub Abstract:
Hair cell loss is the leading cause of hearing and balance disorders in humans. It can be caused by many factors, including... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zallocchi M, Hati S, Xu Z, Hausman W, Liu H, He DZ, Zuo J. Characterization of quinoxaline derivatives for protection against iatrogenically induced hearing loss. JCI Insight. 2021 Mar 8;6(5):141561. doi: 10.1172/jci.insight.141561. |
The enpp4 ectonucleotidase regulates kidney patterning signalling networks in Xenopus embryos
|
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.03.04.433320 Epub:
Not Epub Abstract:
The enpp ectonucleotidases regulate lipidic and purinergic signalling pathways by controlling the extracellular concentrations... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Massé K, Bhamra S, Paroissin C, Maneta-Peyret L, Boué-Grabot E, Jones EA. The enpp4 ectonucleotidase regulates kidney patterning signalling networks in Xenopus embryos. bioRxiv. 2021;[preprint] doi:10.1101/2021.03.04.433320. |
Mechanism and consequences of herpes simplex virus 1-mediated regulation of host mRNA alternative polyadenylation
|
Citation:
PLoS Genet. 2021;17(3):e1009263. doi:10.1371/journal.pgen.1009263 Epub:
Not Epub Abstract:
Eukaryotic gene expression is extensively regulated by cellular stress and pathogen infections. We have previously shown that... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: HEK293 Citation Extract: Wang X, Liu L, Whisnant AW, Hennig T, Djakovic L, Haque N, Bach C, Sandri-Goldin RM, Erhard F, Friedel CC, Dölken L, Shi Y. Mechanism and consequences of herpes simplex virus 1-mediated regulation of host mRNA alternative polyadenylation. PLoS Genet. 2021;17(3):e1009263. doi:10.1371/journal.pgen.1009263. |
Stepwise candidate drug screening for myopia control by using zebrafish, mouse, and Golden Syrian Hamster myopia models
|
Citation:
EBioMedicine. 2021;65:103263. doi:10.1016/j.ebiom.2021.103263 Epub:
Not Epub Abstract:
Background: We developed a preclinical protocol for the screening of candidate drugs able to control myopia and prevent its... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lin M-Y, Lin I-T, Wu Y-C, Wang I-J. Stepwise candidate drug screening for myopia control by using zebrafish, mouse, and Golden Syrian Hamster myopia models. EBioMedicine. 2021;65:103263. doi:10.1016/j.ebiom.2021.103263. |
Conditional gene knockdowns in sea urchins using caged morpholinos
|
Citation:
Dev Biol . 2021 Mar 5;475:21-29. doi: 10.1016/j.ydbio.2021.02.014 Epub:
Not Epub Abstract:
Sea urchins and other echinoderms are important experimental models for analyzing embryonic development, but a lack of spatial... Delivery Method:
microinjection Organism or Cell Type:
sea urchin Citation Extract: Bardhan A, Deiters A, Ettensohn CA. Conditional gene knockdowns in sea urchins using caged morpholinos. Dev Biol . 2021 Mar 5;475:21-29. doi: 10.1016/j.ydbio.2021.02.014. |
The altered expression of neurofilament in mouse models and patients with spinal muscular atrophy
|
Citation:
Ann Clin Transl Neurol. 2021 Mar 8. doi: 10.1002/acn3.51336. Online ahead of print Epub:
Not Epub Abstract:
Objectives: To investigate the levels of neurofilaments (NFs) in transgenic mice and patients with spinal muscular atrophy (SMA... Delivery Method:
subcutaneous (s.c.) injection Organism or Cell Type:
severe SMA mice Citation Extract: Spicer C, Lu CH, Catapano F, Scoto M, Zaharieva I, Malaspina A, Morgan JE, Greensmith L, Muntoni F, Zhou H. The altered expression of neurofilament in mouse models and patients with spinal muscular atrophy. Ann Clin Transl Neurol. 2021 Mar 8. doi: 10.1002/acn3.51336. Online ahead of print. |
Knockdown of hspg2 is associated with abnormal mandibular joint formation and neural crest cell dysfunction in zebrafish
|
Citation:
BMC Dev Biol. 2021 Mar 8;21(1):7. doi: 10.1186/s12861-021-00238-4 Epub:
Not Epub Abstract:
Background: Heparan sulfate proteoglycan 2 (HSPG2) encodes for perlecan, a large proteoglycan that plays an important role in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Castellanos BS, Reyes-Nava NG, Quintana AM. Knockdown of hspg2 is associated with abnormal mandibular joint formation and neural crest cell dysfunction in zebrafish. BMC Dev Biol. 2021 Mar 8;21(1):7. doi: 10.1186/s12861-021-00238-4. |