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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Pluripotency factors determine gene expression repertoire at zygotic genome activation

Authors:
Gao M, Veil M, Rosenblatt M, Gebhard A, Hass H, Buryanova L, Yampolsky LY, Grüning B, Ulianov SV, Timmer J, Onichtchouk D
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2020.02.16.949362
Epub:
Not Epub
Abstract:
Awakening of zygotic transcription in animal embryos relies on maternal pioneer transcription factors. The interplay of global...
Link:
https://www.biorxiv.org/content/10.1101/2020.02.16.949362v3
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gao M, Veil M, Rosenblatt M, Gebhard A, Hass H, Buryanova L, Yampolsky LY, Grüning B, Ulianov SV, Timmer J, Onichtchouk D. Pluripotency factors determine gene expression repertoire at zygotic genome activation. bioRxiv. 2021;[preprint] doi:10.1101/2020.02.16.949362.

Sobp modulates Six1 transcriptional activation and is required during craniofacial development

Authors:
Tavares ALP, Jourdeuil K, Neilson K, Majumdar H, Moody SA
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.05.438472
Epub:
Not Epub
Abstract:
Branchio-oto-renal syndrome (BOR) is a disorder characterized by hearing loss, craniofacial and/or renal defects. Mutations in...
Link:
https://www.biorxiv.org/content/10.1101/2021.04.05.438472v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Tavares ALP, Jourdeuil K, Neilson K, Majumdar H, Moody SA. Sobp modulates Six1 transcriptional activation and is required during craniofacial development. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.05.438472.

Kapd Is Essential for Specification of the Dopaminergic Neurogenesis in Zebrafish Embryos

Authors:
Jung J, Kim E, Rhee M
Citation:
Mol Cells. 2021 Apr 6. doi: 10.14348/molcells.2021.0005. Online ahead of print
Epub:
Yes
Abstract:
To define novel networks of Parkinson's disease (PD) pathogenesis, the substantia nigra pars compacta of A53T mice, where...
Link:
http://www.molcells.org/journal/view.html?doi=10.14348/molcells.2021.0005
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jung J, Kim E, Rhee M. Kapd Is Essential for Specification of the Dopaminergic Neurogenesis in Zebrafish Embryos. Mol Cells. 2021 Apr 6. doi: 10.14348/molcells.2021.0005. Online ahead of print.

Sea urchin larvae utilize light for regulating the pyloric opening

Authors:
Yaguchi J, Yaguchi S
Citation:
BMC Biol. 2021 Apr 6;19(1):64. doi: 10.1186/s12915-021-00999-1
Epub:
Not Epub
Abstract:
Background: Light is essential for various biological activities. In particular, visual information through eyes or eyespots is...
Link:
https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-021-00999-1
Delivery Method:
microinjection
Organism or Cell Type:
Hemicentrotus pulcherrimus (sea urchin)
Citation Extract:
Yaguchi J, Yaguchi S. Sea urchin larvae utilize light for regulating the pyloric opening. BMC Biol. 2021 Apr 6;19(1):64. doi: 10.1186/s12915-021-00999-1.

Rap1b Promotes Notch-Signal-Mediated Hematopoietic Stem Cell Development by Enhancing Integrin-Mediated Cell Adhesion

Authors:
Rho SS, Kobayashi I, Oguri-Nakamura E, Ando K, Fujiwara M, Kamimura N, Hirata H, Iida A, Iwai Y, Mochizuki N, Fukuhara S
Citation:
Dev Cell. 2019 Jun 3;49(5):681-696.e6. doi: 10.1016/j.devcel.2019.03.023. Epub 2019 Apr 18
Epub:
Not Epub
Abstract:
Hematopoietic stem cells (HSCs) emerge from hemogenic endothelium (HE) within the ventral portion of the dorsal aorta during...
Link:
https://www.sciencedirect.com/science/article/pii/S1534580719302345
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rho SS, Kobayashi I, Oguri-Nakamura E, Ando K, Fujiwara M, Kamimura N, Hirata H, Iida A, Iwai Y, Mochizuki N, Fukuhara S. Rap1b Promotes Notch-Signal-Mediated Hematopoietic Stem Cell Development by Enhancing Integrin-Mediated Cell Adhesion. Dev Cell. 2019 Jun 3;49(5):681-696.e6. doi: 10.1016/j.devcel.2019.03.023. Epub 2019 Apr 18.

Novel zebrafish mutants reveal new roles for Apolipoprotein B during embryonic development and pathological conditions

Authors:
Templehof H, Moshe N, Avraham-Davidi I, Yaniv K
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.01.437990
Epub:
Not Epub
Abstract:
Apolipoprotein B (ApoB) is the primary protein of chylomicrons, VLDLs and LDLs and is essential for their assembly. Defects in...
Link:
https://www.biorxiv.org/content/10.1101/2021.04.01.437990v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Templehof H, Moshe N, Avraham-Davidi I, Yaniv K. Novel zebrafish mutants reveal new roles for Apolipoprotein B during embryonic development and pathological conditions. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.01.437990.

The Kunitz-type serine protease inhibitor Spint2 is required for cellular cohesion, coordinated cell migration and cell survival during zebrafish hatching gland development

Authors:
Hatzold J, Wessendorf H, Pogoda H-M, Bloch W, Hammerschmidt M
Citation:
Dev Biol. 2021;[Epub ahead of print] doi: 10.1016/j.ydbio.2021.03.017
Epub:
Yes
Abstract:
We have previously shown that the Kunitz-type serine protease inhibitor Spint1a, also named Hai1a, is required in the zebrafish...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0012160621000774
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hatzold J, Wessendorf H, Pogoda H-M, Bloch W, Hammerschmidt M. The Kunitz-type serine protease inhibitor Spint2 is required for cellular cohesion, coordinated cell migration and cell survival during zebrafish hatching gland development. Dev Biol. 2021;[Epub ahead of print] doi: 10.1016/j.ydbio.2021.03.017.

Haploinsufficiency of the Sin3/HDAC corepressor complex member SIN3B causes a syndromic intellectual disability/autism spectrum disorder

Authors:
Latypova X, Vincent M, Mollé A, Adebambo OA, Fourgeux C, Khan TN, Caro A, Rosello M, Orellana C, Niyazov D, Lederer D, Deprez M, Capri Y, Kannu P, Tabet AC, Levy J, Aten E, den Hollander N, Splitt M, Walia J, Immken LL, Stankiewicz P, McWalter K, Suchy S, Louie RJ, Bell S, Stevenson RE, Rousseau J, Willem C, Retiere C, Yang X-J, Campeau PM, Martinez F, Rosenfeld JA, Le Caignec C, Küry S, Mercier S, Moradkhani K, Conrad S, Besnard T, Cogné B, Katsanis N, Bézieau S, Poschmann J, Davis EE, Isidor B
Citation:
Am J Hum Genet. 2021;108(5):929-41. doi:10.1016/j.ajhg.2021.03.017
Epub:
Not Epub
Abstract:
Proteins involved in transcriptional regulation harbor a demonstrated enrichment of mutations in neurodevelopmental disorders....
Link:
https://www.cell.com/ajhg/fulltext/S0002-9297(21)00101-4
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Latypova X, Vincent M, Mollé A, Adebambo OA, Fourgeux C, Khan TN, Caro A, Rosello M, Orellana C, Niyazov D, Lederer D, Deprez M, Capri Y, Kannu P, Tabet AC, Levy J, Aten E, den Hollander N, Splitt M, Walia J, Immken LL, Stankiewicz P, McWalter K, Suchy S, Louie RJ, Bell S, Stevenson RE, Rousseau J, Willem C, Retiere C, Yang X-J, Campeau PM, Martinez F, Rosenfeld JA, Le Caignec C, Küry S, Mercier S, Moradkhani K, Conrad S, Besnard T, Cogné B, Katsanis N, Bézieau S, Poschmann J, Davis EE, Isidor B. Haploinsufficiency of the Sin3/HDAC corepressor complex member SIN3B causes a syndromic intellectual disability/autism spectrum disorder. Am J Hum Genet. 2021;108(5):929-41. doi:10.1016/j.ajhg.2021.03.017.

Capillarity and active cell movement at mesendoderm translocation in the Xenopus gastrula

Authors:
Nagel M, Barua D, Damm EW, Kashef J, Hofmann R, Ershov A, Cecilia A, Moosmann J, Baumbach T, Winklbauer R
Citation:
Development. 2021 Mar 29;148(18):dev198960. doi: 10.1242/dev.198960
Epub:
Not Epub
Abstract:
During Xenopus gastrulation, leading edge mesendoderm (LEM) advances animally as a wedge-shaped cell mass over the vegetally...
Link:
https://dev.biologists.org/content/148/18/dev198960
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Nagel M, Barua D, Damm EW, Kashef J, Hofmann R, Ershov A, Cecilia A, Moosmann J, Baumbach T, Winklbauer R. Capillarity and active cell movement at mesendoderm translocation in the Xenopus gastrula. Development. 2021 Mar 29;148(18):dev198960. doi: 10.1242/dev.198960.

Loss of splicing factor IK impairs normal skeletal muscle development

Authors:
In Ka H, Seo H, Choi YKim J, Cho M, Choi SY, Park S, Han S, An J, Chung HS, Yang Y, Kim MJ
Citation:
BMC Biol. 2021 Apr 1;19(1):44. doi:10.1186/s12915-021-00980-y
Epub:
Not Epub
Abstract:
Background: IK is a splicing factor that promotes spliceosome activation and contributes to pre-mRNA splicing. Although the...
Link:
https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-021-00980-y
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
In Ka H, Seo H, Choi YKim J, Cho M, Choi SY, Park S, Han S, An J, Chung HS, Yang Y, Kim MJ. Loss of splicing factor IK impairs normal skeletal muscle development. BMC Biol. 2021 Apr 1;19(1):44. doi:10.1186/s12915-021-00980-y.

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