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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Cryo-EM structures of human GMPPA–GMPPB complex reveal how cells maintain GDP-mannose homeostasis
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Citation:
Nat Struct Mol Biol. 2021;28(5):1–12. doi:10.1038/s41594-021-00591-9 Epub:
Not Epub Abstract:
GDP-mannose (GDP-Man) is a key metabolite essential for protein glycosylation and glycophosphatidylinositol anchor synthesis,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zheng L, Liu Z, Wang Y, Yang F, Wang J, Huang W, Qin J, Tian M, Cai X, Liu X, Mo X, Gao N, Jia D. Cryo-EM structures of human GMPPA–GMPPB complex reveal how cells maintain GDP-mannose homeostasis. Nat Struct Mol Biol. 2021;28(5):1–12. doi:10.1038/s41594-021-00591-9. |
A prometastatic splicing program regulated by SNRPA1 interactions with structured RNA elements
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Citation:
Science. 2021;372(6543): doi:10.1126/science.abc7531 Epub:
Not Epub Abstract:
Aberrant alternative splicing is a hallmark of cancer, yet the underlying regulatory programs that control this process remain... Delivery Method:
Endo-Porter Organism or Cell Type:
Cell culture: HCC1806-LM2 , MDA-LM2 Citation Extract: Fish L, Khoroshkin M, Navickas A, Garcia K, Culbertson B, Hänisch B, Zhang S, Nguyen CB, Soto LM, Dermit M, Mardakheh FK, Molina H, Alarcón C, Najafabadi HS, Goodarzi H. A prometastatic splicing program regulated by SNRPA1 interactions with structured RNA elements. Science. 2021;372(6543): doi:10.1126/science.abc7531. |
Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis
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Citation:
Science. 2021;372(6543):716-21. doi:10.1126/science.aaz2740 Epub:
Not Epub Abstract:
Transcription and metabolism both influence cell function, but dedicated transcriptional control of metabolic pathways that... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rossmann MP, Hoi K, Chan V, Abraham BJ, Yang S, Mullahoo J, Papanastasiou M, Wang Y, Elia I, Perlin JR, Hagedorn EJ, Hetzel S, Weigert R, Vyas S, Nag PP, Sullivan LB, Warren CR, Dorjsuren B, Greig EC, Adatto I, Cowan CA, Schreiber SL, Young RA, Meissner A, Haigis MC, Hekimi S, Carr SA, Zon LI. Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis. Science. 2021;372(6543):716-21. doi:10.1126/science.aaz2740. |
Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.02.438148 Epub:
Not Epub Abstract:
RUNX1 is essential for the generation of hematopoietic stem cells (HSCs). Runx1 null mouse embryos lack definitive... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bresciani E, Carrington B, Yu K, Kim EM, Zhen T, Guzman VS, Broadbridge E, Bishop K, Kirby M, Harper U, Wincovitch S, Dell’Orso S, Sartorelli V, Sood R, Liu P. Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.02.438148 . |
Maternal and zygotic factors sequentially shape the tissue regionalization of chromatin landscapes in early vertebrate embryos
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.14.439777 Epub:
Not Epub Abstract:
One of the first steps in cellular differentiation of vertebrate embryos is the formation of the three germ layers. Maternal... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Paraiso KD, Blitz IL, Cho KWY. Maternal and zygotic factors sequentially shape the tissue regionalization of chromatin landscapes in early vertebrate embryos. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.14.439777. |
Somite morphogenesis is required for axial blood vessel formation
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Citation:
bioRxiv. 2021;[preprint] doi:/10.1101/2021.04.07.438831 Epub:
Not Epub Abstract:
Angioblasts that form the major axial blood vessels of the dorsal aorta and cardinal vein migrate towards the embryonic midline... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Paulissen E, Waxman JS, Martin BL. Somite morphogenesis is required for axial blood vessel formation. bioRxiv. 2021;[preprint] doi:/10.1101/2021.04.07.438831. |
Sox8 is sufficient to reprogram ectoderm into ear vesicles and associated neurons
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.20.440617 Epub:
Not Epub Abstract:
The vertebrate inner ear arises from a pool of progenitors with the potential to give rise to all the sense organs and cranial... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Buzzi AL, Chen J, Thiery A, Delile J, Streit A. Sox8 is sufficient to reprogram ectoderm into ear vesicles and associated neurons. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.20.440617 . |
Involvement of Huntingtin in Development and Ciliary Beating Regulation of Larvae of the Sea Urchin, Hemicentrotus pulcherrimus
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Citation:
Int J Mol Sci. 2021;22(10):5116. doi:10.3390/ijms22105116 Epub:
Not Epub Abstract:
The multiple functions of the wild type Huntington’s disease protein of the sea urchin Hemicentrotus pulcherrimus (Hp-Htt) have... Delivery Method:
Endo-Porter PEG Organism or Cell Type:
Hemicentrotus pulcherrimus (sea urchin) Citation Extract: Katow H, Katow T, Yoshida H, Kiyomoto M. Involvement of Huntingtin in Development and Ciliary Beating Regulation of Larvae of the Sea Urchin, Hemicentrotus pulcherrimus. Int J Mol Sci. 2021;22(10):5116. doi:10.3390/ijms22105116. |
Knockdown of miR-26a in Zebrafish Leads to Impairment of the Anti-Inflammatory Function of TnP in the Control of Neutrophilia
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Citation:
Fish Shellfish Immunol. 2021;[Epub] doi:10.1016/j.fsi.2021.04.029 Epub:
Yes Abstract:
Our recent data show the valuable potential of TnP for the development of a new and safe anti-inflammatory drug due to its... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Falcao MAP, Walker COB, Disner GR, Batista-Filho J, Soares ABS, Balan-Lima L, Lima C, Lopes-Ferreira M. Knockdown of miR-26a in Zebrafish Leads to Impairment of the Anti-Inflammatory Function of TnP in the Control of Neutrophilia. Fish Shellfish Immunol. 2021;[Epub] doi:10.1016/j.fsi.2021.04.029. |
Identification of Zebrafish Ortholog for Human Coagulation Factor IX and its Age-dependent Expression
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Citation:
J Thromb Haemost. 2021 May 11. doi: 10.1111/jth.15365. Online ahead of print Epub:
Yes Abstract:
Background: Coagulation factor IX (FIX) is a serine protease zymogen involved in the intrinsic blood coagulation pathway, and... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
zebrafish Citation Extract: Iyer N, Al Qaryoute A, Kacham M, Jagadeeswaran P. Identification of Zebrafish Ortholog for Human Coagulation Factor IX and its Age-dependent Expression. J Thromb Haemost. 2021 May 11. doi: 10.1111/jth.15365. Online ahead of print. |