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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Transient ribosome slowdown at the decoding step triggers mRNA degradation independent of Znf598 in zebrafish
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.12.443743 Epub:
Not Epub Abstract:
The control of mRNA stability plays a central role in regulating gene expression patterns. Recent studies have revealed that... Organism or Cell Type:
zebrafish Citation Extract: Mishima Y, Han P, Kimura S, Iwasaki S. Transient ribosome slowdown at the decoding step triggers mRNA degradation independent of Znf598 in zebrafish. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.12.443743. |
The STING ligand 2′3′-cGAMP induces an NF-κB-dependent anti-bacterial innate immune response in the starlet sea anemone Nematostella vectensis
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.13.443009 Epub:
Not Epub Abstract:
In mammals, the cGAS-cGAMP-STING pathway is crucial for sensing viral infection and initiating an anti-viral type I interferon... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (anemone) Citation Extract: Margolis SR, Dietzen PA, Hayes BM, Wilson SC, Remick BC, Chou S, Vance RE. The STING ligand 2′3′-cGAMP induces an NF-κB-dependent anti-bacterial innate immune response in the starlet sea anemone Nematostella vectensis. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.13.443009. |
Slit2 is necessary for optic axon organization in the zebrafish ventral midline
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Citation:
Cells Dev. 2021 Apr 10;166:203677. doi: 10.1016/j.cdev.2021.203677. Online ahead of print Epub:
Not Epub Abstract:
Slit-Robo signaling has been implicated in regulating several steps of retinal ganglion cell axon guidance, with a central role... Organism or Cell Type:
zebrafish Citation Extract: Davison C, Zolessi FR. Slit2 is necessary for optic axon organization in the zebrafish ventral midline. Cells Dev. 2021 Apr 10;166:203677. doi: 10.1016/j.cdev.2021.203677. Online ahead of print. |
Role of vertebrate GAGA associated factor (vGAF) in early development of zebrafish
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Citation:
Cells Dev. 2021 Apr 24;166:203682. doi: 10.1016/j.cdev.2021.203682. Online ahead of print Epub:
Not Epub Abstract:
Homeotic genes and their genomic organization show remarkable conservation across bilaterians. Consequently, the regulatory... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Matharu NK, Yadav S, Kumar M, Mishra RK. Role of vertebrate GAGA associated factor (vGAF) in early development of zebrafish. Cells Dev. 2021 Apr 24;166:203682. doi: 10.1016/j.cdev.2021.203682. Online ahead of print. |
Molluscan dorsal-ventral patterning relying on bmp2/4 and chordin provides insights into spiralian development and bilaterian evolution
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.11.245670 Epub:
Not Epub Abstract:
Although a conserved mechanism relying on bmp2/4 and chordin is suggested in animal dorsal-ventral (DV) patterning, this... Delivery Method:
microinjection Organism or Cell Type:
Lottia goshimai (mollusk) Citation Extract: Tan S, Huan P, Liu B. Molluscan dorsal-ventral patterning relying on bmp2/4 and chordin provides insights into spiralian development and bilaterian evolution. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.11.245670 . |
Targeted SMN Exon Skipping: A Useful Control to Assess In Vitro and In Vivo Splice-Switching Studies
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Citation:
Biomedicines. 2021;9(5):552. doi:10.3390/biomedicines9050552 Epub:
Not Epub Abstract:
The literature surrounding the use of antisense oligonucleotides continues to grow, with new disease and mechanistic... Delivery Method:
cell bathing, subcutaneous and intraperitoneal (s.c. & i.p.) injection Organism or Cell Type:
cell culture: human fibroblasts, SH-SY5Y neuroblastoma, mdx myoblasts; mice Citation Extract: Flynn LL, Mitrpant C, Adams A, Pitout IL, Stirnweiss A, Fletcher S, Wilton SD. Targeted SMN Exon Skipping: A Useful Control to Assess In Vitro and In Vivo Splice-Switching Studies. Biomedicines. 2021;9(5):552. doi:10.3390/biomedicines9050552. |
Insm1-expressing neurons and secretory cells develop from a common pool of progenitors in the sea anemone Nematostella vectensis
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.09.439178 Epub:
Not Epub Abstract:
Neurons are highly specialized cells present in nearly all animals, but their evolutionary origin and relationship to other... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (cniderian) Citation Extract: Tournière O, Busengdal H, Gahan JM, Rentzsch F. Insm1-expressing neurons and secretory cells develop from a common pool of progenitors in the sea anemone Nematostella vectensis. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.09.439178. |
Myeloid and endothelial cells cooperate to promote hematopoietic stem cells expansion in the fetal niche
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.07.438809 Epub:
Not Epub Abstract:
During embryonic development, very few hematopoietic stem cells (HSCs) are produced from the hemogenic endothelium, that will... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cacialli P, Mailhe M-P, Golub R, Bertrand JY. Myeloid and endothelial cells cooperate to promote hematopoietic stem cells expansion in the fetal niche. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.07.438809. |
Surrogate production of genome edited sperm from a different subfamily by spermatogonial stem cell transplantation
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.20.440715 Epub:
Not Epub Abstract:
The surrogate reproduction technique provides a powerful tool for production of allogenic or xenogeneic gametes derived from... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang F, Li X, Hao Y, Li Y, Ye D, He M, Wang H, Zhu Z, Sun Y. Surrogate production of genome edited sperm from a different subfamily by spermatogonial stem cell transplantation. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.20.440715. |
TBX5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.09.439219 Epub:
Not Epub Abstract:
The gene regulatory networks that coordinate the development of the cardiac and pulmonary systems are essential for terrestrial... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis, Xenopus tropicalis Citation Extract: Rankin SA, Steimle JD, Yang XH, Rydeen AB, Agarwal K, Chaturvedi P, Ikegami K, Herriges MJ, Moskowitz IP, Zorn AM. TBX5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.09.439219. |