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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements

Authors:
Jessen JR, Topczewski J, Bingham S, Sepich DS, Marlow F, Chandrasekhar A, Solnica-Krezel L
Citation:
Nat Cell Biol. 2002 Aug;4(8):610-5
Epub:
Not Epub
Abstract:
Embryonic morphogenesis is driven by a suite of cell behaviours, including coordinated shape changes, cellular rearrangements...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jessen JR, Topczewski J, Bingham S, Sepich DS, Marlow F, Chandrasekhar A, Solnica-Krezel L. Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements. Nat Cell Biol. 2002 Aug;4(8):610-5.

A role for iro1 and iro7 in the establishment of an anteroposterior compartment of the ectoderm adjacent to the midbrain-hindbrain boundary

Authors:
Itoh M, Kudoh T, Dedekian M, Kim CH, Chitnis AB
Citation:
Development. 2002 May;129(10):2317-27
Epub:
Not Epub
Abstract:
We have identified a novel Iroquois (Iro) gene, iro7, in zebrafish. iro7 is expressed during gastrulation along with iro1 in a...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Itoh M, Kudoh T, Dedekian M, Kim CH, Chitnis AB. A role for iro1 and iro7 in the establishment of an anteroposterior compartment of the ectoderm adjacent to the midbrain-hindbrain boundary. Development. 2002 May;129(10):2317-27.

Angiogenic network formation in the developing vertebrate trunk

Authors:
Isogai S, Lawson ND, Torrealday S, Horiguchi M, Weinstein BM
Citation:
Development. 2003 Nov;130(21):5281-90. Epub 2003 Sep 3
Epub:
Not Epub
Abstract:
We have used time-lapse multiphoton microscopy of living Tg(fli1:EGFP)y1 zebrafish embryos to examine how a patterned,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Isogai S, Lawson ND, Torrealday S, Horiguchi M, Weinstein BM. Angiogenic network formation in the developing vertebrate trunk. Development. 2003 Nov;130(21):5281-90. Epub 2003 Sep 3.

ATF6α/β-mediated Adjustment of ER Chaperone Levels Is Essential for Development of the Notochord in Medaka Fish

Authors:
Ishikawa T, Okada T, Ishikawa-Fujiwara T, Todo T, Kamei Y, Shigenobu S, Tanaka M, Saito TL, Yoshimura J, Morishita S, Toyoda A, Sakaki Y, Taniguchi Y, Takeda S, Mori K
Citation:
Mol Biol Cell. 2013 May;24(9):1387-95. doi: 10.1091/mbc.E12-11-0830. Epub 2013 Feb 27.
Epub:
Not Epub
Abstract:
ATF6α and ATF6β are membrane-bound transcription factors which are activated by regulated intramembrane proteolysis in response...
Delivery Method:
Microinjection
Organism or Cell Type:
medaka
Citation Extract:
Ishikawa T, Okada T, Ishikawa-Fujiwara T, Todo T, Kamei Y, Shigenobu S, Tanaka M, Saito TL, Yoshimura J, Morishita S, Toyoda A, Sakaki Y, Taniguchi Y, Takeda S, Mori K. ATF6α/β-mediated Adjustment of ER Chaperone Levels Is Essential for Development of the Notochord in Medaka Fish. Mol Biol Cell. 2013 May;24(9):1387-95. doi: 10.1091/mbc.E12-11-0830. Epub 2013 Feb 27..

BcI-xL antisense treatment sensitizes Bcl-xL-overexpressing squamous cell carcinoma cells to carboplatin

Authors:
Itoh M, Noutomi T, Chiba H, Mizuguchi J
Citation:
Oral Oncol. 2002 Dec;38(8):752-6
Epub:
Not Epub
Abstract:
Carboplatin (CBDCA) has been widely used for the treatment of oral squamous cell carcinoma (SCC). The Bcl-2 family member Bcl-...
Delivery Method:
Scrape Delivery
Organism or Cell Type:
cell culture: squamous cell carcinoma
Citation Extract:
Itoh M, Noutomi T, Chiba H, Mizuguchi J. BcI-xL antisense treatment sensitizes Bcl-xL-overexpressing squamous cell carcinoma cells to carboplatin. Oral Oncol. 2002 Dec;38(8):752-6.

Blockade of thrombospondin-1-CD47 interactions prevents necrosis of full thickness skin grafts.

Authors:
Isenberg JS, Pappan LK, Romeo MJ, Abu-Asab M, Tsokos M, Wink DA, Frazier WA, Roberts DD
Citation:
Ann. Surg. 247(1):180-190, 2008.
Epub:
Not Epub
Abstract:
BACKGROUND: Skin graft survival and healing requires rapid restoration of blood flow to the avascular graft. Failure or delay...
Delivery Method:
in vivo: injection
Organism or Cell Type:
mice
Citation Extract:
Isenberg JS, Pappan LK, Romeo MJ, Abu-Asab M, Tsokos M, Wink DA, Frazier WA, Roberts DD. Blockade of thrombospondin-1-CD47 interactions prevents necrosis of full thickness skin grafts.. Ann. Surg. 247(1):180-190, 2008..

Blocking thrombospondin-1/CD47 signaling alleviates deleterious effects of aging on tissue responses to ischemia.

Authors:
Isenberg JS, Hyodo F, Pappan LK, Abu-Asab M, Tsokos M, Krishna MC, Frazier WA, Roberts DD
Citation:
Arterioscler. Thromb. Vasc. Biol. 27:2582-2588, 2007
Epub:
Not Epub
Abstract:
OBJECTIVE: Decreased blood flow secondary to peripheral vascular disease underlies a significant number of chronic diseases...
Delivery Method:
In vitro: transfection; in vivo: intramuscular injection
Organism or Cell Type:
mice
Citation Extract:
Isenberg JS, Hyodo F, Pappan LK, Abu-Asab M, Tsokos M, Krishna MC, Frazier WA, Roberts DD. Blocking thrombospondin-1/CD47 signaling alleviates deleterious effects of aging on tissue responses to ischemia.. Arterioscler. Thromb. Vasc. Biol. 27:2582-2588, 2007.

Cellular Uptake of Neutral Phosphorodiamidate Morpholino Oligomers

Authors:
Iversen PL, Aird KM, Wu R, Morse MM, Devi GR
Citation:
Curr Pharm Biotechnol. 2009 Sep;10(6):579-88. Epub 2009 Sep 1.
Epub:
Not Epub
Abstract:
Phosphorodiamidate morpholino oligomers (PMO), which have a neutral chemistry, are extensively being used as tools for...
Organism or Cell Type:
cell culture
Citation Extract:
Iversen PL, Aird KM, Wu R, Morse MM, Devi GR. Cellular Uptake of Neutral Phosphorodiamidate Morpholino Oligomers. Curr Pharm Biotechnol. 2009 Sep;10(6):579-88. Epub 2009 Sep 1..

Close association of carbonic anhydrase (CA2a & CA15a), Na+/H+ exchanger (Nhe3b), and ammonia transporter Rhcg1 in zebrafish ionocytes responsible for Na+ uptake

Authors:
Ito Y, Kobayashi S, Nakamura N, Esaki M, Miyagi H, Hoshijima K, Hirose S
Citation:
Frontiers in Physiology. 2013;4(59) doi:10.3389/fphys.2013.00059
Epub:
Not Epub
Abstract:
Freshwater (FW) fishes actively absorb salt from their environment to tolerate low salinities. We previously reported that...
Organism or Cell Type:
zebrafish
Citation Extract:
Ito Y, Kobayashi S, Nakamura N, Esaki M, Miyagi H, Hoshijima K, Hirose S. Close association of carbonic anhydrase (CA2a & CA15a), Na+/H+ exchanger (Nhe3b), and ammonia transporter Rhcg1 in zebrafish ionocytes responsible for Na+ uptake. Frontiers in Physiology. 2013;4(59) doi:10.3389/fphys.2013.00059.

Combined zebrafish-yeast chemical-genetic screens reveal gene-copper-nutrition interactions that modulate melanocyte pigmentation

Authors:
Ishizaki H, Spitzer M, Wildenhain J, Anastasaki C, Zeng Z, Dolma S, Shaw M, Madsen E, Gitlin J, Marais R, Tyers M, Patton EE
Citation:
Dis Model Mech. 2010 Sep-Oct;3(9-10):639-51. doi: 10.1242/dmm.005769. Epub 2010 Aug 16.
Epub:
Not Epub
Abstract:
Hypopigmentation is a feature of copper deficiency in humans, as caused by mutation of the copper (Cu(2+)) transporter ATP7A in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ishizaki H, Spitzer M, Wildenhain J, Anastasaki C, Zeng Z, Dolma S, Shaw M, Madsen E, Gitlin J, Marais R, Tyers M, Patton EE. Combined zebrafish-yeast chemical-genetic screens reveal gene-copper-nutrition interactions that modulate melanocyte pigmentation. Dis Model Mech. 2010 Sep-Oct;3(9-10):639-51. doi: 10.1242/dmm.005769. Epub 2010 Aug 16..

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