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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Reverse Effect of Mammalian Hypocalcemic Cortisol in Fish: Cortisol Stimulates Ca2+ Uptake via Glucocorticoid Receptor-Mediated Vitamin D3 Metabolism

Authors:
Lin CH, Tsai IL, Su CH, Tseng DY, Hwang PP
Citation:
PLoS ONE. 2011;6(8): e23689. doi:10.1371/journal.pone.0023689
Epub:
Not Epub
Abstract:
Cortisol was reported to downregulate body-fluid Ca2+ levels in mammals but was proposed to show hypercalcemic effects in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin CH, Tsai IL, Su CH, Tseng DY, Hwang PP. Reverse Effect of Mammalian Hypocalcemic Cortisol in Fish: Cortisol Stimulates Ca2+ Uptake via Glucocorticoid Receptor-Mediated Vitamin D3 Metabolism. PLoS ONE. 2011;6(8): e23689. doi:10.1371/journal.pone.0023689.

Serotonin stimulation of cAMP-dependent plasticity in Aplysia sensory neurons is mediated by calmodulin-sensitive adenylyl cyclase

Authors:
Lin AH, Cohen JE, Wan Q, Niu K, Shrestha P, Bernstein SL, Abrams TW
Citation:
Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15607-12. Epub 2010 Aug 11
Epub:
Not Epub
Abstract:
Calmodulin (CaM)-sensitive adenylyl cyclase (AC) in sensory neurons (SNs) in Aplysia has been proposed as a molecular...
Delivery Method:
in vivo injection into neurons
Organism or Cell Type:
Aplysia
Citation Extract:
Lin AH, Cohen JE, Wan Q, Niu K, Shrestha P, Bernstein SL, Abrams TW. Serotonin stimulation of cAMP-dependent plasticity in Aplysia sensory neurons is mediated by calmodulin-sensitive adenylyl cyclase. Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15607-12. Epub 2010 Aug 11.

Spacer-length dependence of programmed −1 or −2 ribosomal frameshifting on a U6A heptamer supports a role for messenger RNA (mRNA) tension in frameshifting

Authors:
Lin Z, Gilbert RJC, Brierley I
Citation:
Nucl. Acids Res. 2012 June 28. [Epub ahead of print] doi:10.1093/nar/gks629
Epub:
Not Epub
Abstract:
Programmed −1 ribosomal frameshifting is employed in the expression of a number of viral and cellular genes. In this process,...
Organism or Cell Type:
Cell culture: COS-7 cells (monkey kidney)
Citation Extract:
Lin Z, Gilbert RJC, Brierley I. Spacer-length dependence of programmed −1 or −2 ribosomal frameshifting on a U6A heptamer supports a role for messenger RNA (mRNA) tension in frameshifting. Nucl. Acids Res. 2012 June 28. [Epub ahead of print] doi:10.1093/nar/gks629 .

Successful Radiotherapy of Tumor in Pretargeted Mice by 188Re-Radiolabeled Phosphorodiamidate Morpholino Oligomer, a Synthetic DNA Analogue

Authors:
Liu G, Dou S, Mardirossian G, He J, Zhang S, Liu X, Rusckowski M, Hnatowich DJ
Citation:
Clin Cancer Res. 2006 Aug 15;12(16):4958-4964
Epub:
Not Epub
Abstract:
PURPOSE: Pretargeting has been attracting increasing attention as a drug delivery approach. We recently proposed Watson-Crick...
Delivery Method:
Injection
Organism or Cell Type:
mice
Citation Extract:
Liu G, Dou S, Mardirossian G, He J, Zhang S, Liu X, Rusckowski M, Hnatowich DJ. Successful Radiotherapy of Tumor in Pretargeted Mice by 188Re-Radiolabeled Phosphorodiamidate Morpholino Oligomer, a Synthetic DNA Analogue. Clin Cancer Res. 2006 Aug 15;12(16):4958-4964.

Systemic splicing factor deficiency causes tissue-specific defects: a zebrafish model for retinitis pigmentosa

Authors:
Linder B, Dill H, Hirmer A, Brocher J, Lee GP, Mathavan S, Bolz HJ, Winkler C, Laggerbauer B, Fischer U
Citation:
Hum Mol Genet. 2010 Nov 25. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Retinitis pigmentosa (RP) is a common hereditary eye disease that causes blindness due to a progressive loss of photoreceptors...
Organism or Cell Type:
zebrafish
Citation Extract:
Linder B, Dill H, Hirmer A, Brocher J, Lee GP, Mathavan S, Bolz HJ, Winkler C, Laggerbauer B, Fischer U. Systemic splicing factor deficiency causes tissue-specific defects: a zebrafish model for retinitis pigmentosa. Hum Mol Genet. 2010 Nov 25. [Epub ahead of print].

TAK1 promotes BMP4/Smad1 signaling via inhibition of erk MAPK: A new link in the FGF/BMP regulatory network

Authors:
Liu C, Goswami M, Talley J, Chesser-Martinez PL, Lou CH, Sater AK
Citation:
Differentiation. 2012 Mar 1;83(4):210-219. [Epub ahead of print]
Epub:
Not Epub
Abstract:
FGFs and BMPs act in concert to regulate a wide range of processes in vertebrate development. In most cases, FGFs and BMPs have...
Organism or Cell Type:
Xenopus
Citation Extract:
Liu C, Goswami M, Talley J, Chesser-Martinez PL, Lou CH, Sater AK. TAK1 promotes BMP4/Smad1 signaling via inhibition of erk MAPK: A new link in the FGF/BMP regulatory network. Differentiation. 2012 Mar 1;83(4):210-219. [Epub ahead of print].

The Cell Neural Adhesion Molecule Contactin-2 (TAG-1) Is Beneficial for Functional Recovery after Spinal Cord Injury in Adult Zebrafish

Authors:
Lin JF, Pan HC, Ma LP, Shen YQ, Schachner M
Citation:
PLoS ONE. 2012;7(12):e52376. doi:10.1371/journal.pone.0052376
Epub:
Not Epub
Abstract:
The cell neural adhesion molecule contactin-2 plays a key role in axon extension and guidance, fasciculation, and myelination...
Delivery Method:
Vivo-Morpholino in Gelfoam
Organism or Cell Type:
zebrafish
Citation Extract:
Lin JF, Pan HC, Ma LP, Shen YQ, Schachner M. The Cell Neural Adhesion Molecule Contactin-2 (TAG-1) Is Beneficial for Functional Recovery after Spinal Cord Injury in Adult Zebrafish. PLoS ONE. 2012;7(12):e52376. doi:10.1371/journal.pone.0052376.

The Critical Role of Protein Arginine Methyltransferase prmt8 in Zebrafish Embryonic and Neural Development Is Non-Redundant with Its Paralogue prmt1

Authors:
Lin Y-l, Tsai Y-J, Liu Y-F, Cheng Y-C, Hung C-M, Lee Y-J, Pan H, Li C
Citation:
PLoS ONE. 2013;8(3):e55221. doi:10.1371/journal.pone.0055221
Epub:
Not Epub
Abstract:
Protein arginine methyltransferase (PRMT) 1 is the most conserved and widely distributed PRMT in eukaryotes. PRMT8 is a...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin Y-l, Tsai Y-J, Liu Y-F, Cheng Y-C, Hung C-M, Lee Y-J, Pan H, Li C. The Critical Role of Protein Arginine Methyltransferase prmt8 in Zebrafish Embryonic and Neural Development Is Non-Redundant with Its Paralogue prmt1. PLoS ONE. 2013;8(3):e55221. doi:10.1371/journal.pone.0055221.

The influence of chain length and base sequence on the pharmacokinetic behavior of 99mTc-morpholinos in mice

Authors:
Liu G, Zhang S, He J, Liu N, Gupta S, Rusckowski M, Hnatowich DJ.
Citation:
Q J Nucl Med. 2002 Sep;46(3):233-43
Epub:
Not Epub
Abstract:
BACKGROUND: Despite in vivo use now over several years, in particular for nuclear medicine imaging, the influences on...
Citation Extract:
Liu G, Zhang S, He J, Liu N, Gupta S, Rusckowski M, Hnatowich DJ.. The influence of chain length and base sequence on the pharmacokinetic behavior of 99mTc-morpholinos in mice. Q J Nucl Med. 2002 Sep;46(3):233-43.

The ratio of maximum percent tumor accumulations of the pretargeting agent and the radiolabeled effector is independent of tumor size

Authors:
Liu G, Dou S, Liang M, Chen X, Rusckowski R, Hnatowich DJ
Citation:
Eur J Cancer. 2009 Nov;45(17):3098-103. doi: 10.1016/j.ejca.2009.09.007. Epub 2009 Oct 5
Epub:
Not Epub
Abstract:
Our previous studies have indicated that the optimal dosage ratio of pretargeting antibody to effector is proportional to their...
Link:
http://www.ejcancer.com/article/S0959-8049%2809%2900679-0/abstract
Citation Extract:
Liu G, Dou S, Liang M, Chen X, Rusckowski R, Hnatowich DJ. The ratio of maximum percent tumor accumulations of the pretargeting agent and the radiolabeled effector is independent of tumor size. Eur J Cancer. 2009 Nov;45(17):3098-103. doi: 10.1016/j.ejca.2009.09.007. Epub 2009 Oct 5.

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