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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Solid Phase Synthesis of Casimersen and Its 3ʹ-end Modification for Therapeutic Benefits
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Citation:
ChemRxiv [preprint]. 2025; doi:10.26434/chemrxiv-2025-mf99n Epub:
Not Epub Abstract:
Phosphorodiamidate Morpholino Oligonucleotides (PMO) have been well established in the treatment of muscular dystrophies with... Delivery Method:
None Organism or Cell Type:
None Citation Extract: Sinha S, Das A, Pratihar S, Nath Sharma S, Kundu J. Solid Phase Synthesis of Casimersen and Its 3ʹ-end Modification for Therapeutic Benefits. ChemRxiv [preprint]. 2025; doi:10.26434/chemrxiv-2025-mf99n. |
Yellow catfish (Pelteobagrus fulvidraco) lacking of germ cells exhibited gonadal sexual dimorphism
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Citation:
Aquaculture. Online 28 January 2025 Epub:
Not Epub Abstract:
Yellow catfish (Pelteobagrus fulvidraco) is a valuable freshwater aquaculture species in China, characterized by an XX/XY sex... Delivery Method:
microinjection Organism or Cell Type:
catfish Citation Extract: Ye H, Hou Y, Huang L, Yue H, Qu Z, Ruan R, Li C. Yellow catfish (Pelteobagrus fulvidraco) lacking of germ cells exhibited gonadal sexual dimorphism. Aquaculture. Online 28 January 2025. |
Combined loss of glyoxalase 1 and aldehyde dehydrogenase 3a1 amplifies dicarbonyl stress, impairs proteasome activity resulting in hyperglycemia and activated retinal angiogenesis
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Citation:
Metabolism. 2025 Jan 30:156149. doi: 10.1016/j.metabol.2025.156149. Epub ahead of print. PMID: 39892865 Epub:
Not Epub Abstract:
Background & aims: Any energy consumption results in the generation of highly reactive dicarbonyls and the need to prevent... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li S, Li H, Bennewitz K, Poschet G, Buettner M, Hausser I, Szendroedi J, Nawroth PP, Kroll J. Combined loss of glyoxalase 1 and aldehyde dehydrogenase 3a1 amplifies dicarbonyl stress, impairs proteasome activity resulting in hyperglycemia and activated retinal angiogenesis. Metabolism. 2025 Jan 30:156149. doi: 10.1016/j.metabol.2025.156149. Epub ahead of print. PMID: 39892865. |
Peptidoglycan recognition protein PGRP-5 is involved in immune defence and neuro-behavioral disorders in zebrafish embryos
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Citation:
PLoS One. 2025 Jan 31;20(1):e0315714. doi: 10.1371/journal.pone.0315714. PMID: 39888929; PMCID: PMC11785313 Epub:
Not Epub Abstract:
Peptidoglycan recognition proteins (PGRPs) are the evolutionarily highly conserved class of pattern recognition receptors,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li X, Xiong G, Luo M, Mao S, Zhang R, Meng Z, Li J, Liao X. Peptidoglycan recognition protein PGRP-5 is involved in immune defence and neuro-behavioral disorders in zebrafish embryos. PLoS One. 2025 Jan 31;20(1):e0315714. doi: 10.1371/journal.pone.0315714. PMID: 39888929; PMCID: PMC11785313. |
Monocyte-Derived cxcl12 Guides a Directional Migration of Blood Vessels in Zebra Fish
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Citation:
Arterioscler Thromb Vasc Biol. 2025 Jan 23. doi: 10.1161/ATVBAHA.124.321588. Epub ahead of print. PMID: 39846165 Epub:
Not Epub Abstract:
Background: Sprouting blood vessels, reaching the aimed location, and establishing the proper connections are vital for... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lu X, Wang X, Li B, Wang X, Duan X, Liu D. Monocyte-Derived cxcl12 Guides a Directional Migration of Blood Vessels in Zebra Fish. Arterioscler Thromb Vasc Biol. 2025 Jan 23. doi: 10.1161/ATVBAHA.124.321588. Epub ahead of print. PMID: 39846165. |
Knockdown of zebrafish tmem242 enhances the production of ROS that signals to increase f9a expression resulting in DIC-like condition
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Citation:
Sci Rep. 2025 Jan 24;15(1):3058. doi: 10.1038/s41598-025-87117-1. PMID: 39856164; PMCID: PMC11761473 Epub:
Not Epub Abstract:
Transmembrane proteins (TMEMs) are embedded in cell membranes and often have poorly understood functions. Our RNAseq analysis... Delivery Method:
Vivo-Morpholino piggyback hybrid; intravenous (i.v.) Organism or Cell Type:
zebrafish Citation Extract: Deebani A, Mary J, Dhinoja S, Al Qaryoute A, Fallatah W, Jagadeeswaran P. Knockdown of zebrafish tmem242 enhances the production of ROS that signals to increase f9a expression resulting in DIC-like condition. Sci Rep. 2025 Jan 24;15(1):3058. doi: 10.1038/s41598-025-87117-1. PMID: 39856164; PMCID: PMC11761473. |
Supracellular contractility in Xenopus laevis embryonic epithelia regulated by extracellular nucleotides and the purinergic G-protein coupled receptor P2Y2
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Citation:
bioRxiv [preprint] 2025.01.21.634176; doi: https://doi.org/10.1101/2025.01.21.634176 Epub:
Not Epub Abstract:
Extracellular signals regulate epithelial homeostasis, cell fate and pattern cell behaviors during embryogenesis, wound healing... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Joshi SD, Jackson TR, Zhang L, Stuckenholz C, Davidson LA. Supracellular contractility in Xenopus laevis embryonic epithelia regulated by extracellular nucleotides and the purinergic G-protein coupled receptor P2Y2. bioRxiv [preprint] 2025.01.21.634176; doi: https://doi.org/10.1101/2025.01.21.634176. |
PRMT1-methylated MSX1 phase separates to control palate development
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Citation:
Nat Commun. 2025 Jan 22;16(1):949. doi: 10.1038/s41467-025-56327-6. PMID: 39843447; PMCID: PMC11754605 Epub:
Not Epub Abstract:
Little is known about the regulation and function of phase separation in craniofacial developmental disorders. MSX1 mutations... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Meng L, Jiang Y, You J, Chen Y, Guo S, Chen L, Ma J. PRMT1-methylated MSX1 phase separates to control palate development. Nat Commun. 2025 Jan 22;16(1):949. doi: 10.1038/s41467-025-56327-6. PMID: 39843447; PMCID: PMC11754605. |
Nephronectin Is Required for Vascularization in Zebrafish and Sufficient to Promote Mammalian Vessel-Like Structures in Hydrogels for Tissue Engineering
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Citation:
J Am Heart Assoc. 2025 Jan 23:e037943. doi: 10.1161/JAHA.123.037943. Epub ahead of print. PMID: 39846290 Epub:
Not Epub Abstract:
Background: Organs and tissues need to be vascularized during development. Similarly, vascularization is required to engineer... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Patra C, Rayrikar A, Wagh G, Kleefeldt F, Roshanbinfar K, Cop F, Nikolic I, Schmidt MHH, Acker-Palmer A, Ergün S, Engel FB. Nephronectin Is Required for Vascularization in Zebrafish and Sufficient to Promote Mammalian Vessel-Like Structures in Hydrogels for Tissue Engineering. J Am Heart Assoc. 2025 Jan 23:e037943. doi: 10.1161/JAHA.123.037943. Epub ahead of print. PMID: 39846290. |
Dual role of Xenopus Odf2 in multiciliated cell patterning and differentiation
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Citation:
Dev Biol. 2025 Apr;520:224-238. doi: 10.1016/j.ydbio.2025.01.014. Epub 2025 Jan 24. PMID: 39864486 Epub:
Not Epub Abstract:
In developing tissues, the number, position, and differentiation of cells must be coordinately controlled to ensure the... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Nommick A, Chuyen A, Clément R, Thomé V, Daian F, Rosnet O, Richard F, Brouilly N, Loiseau E, Boutin C, Kodjabachian L. Dual role of Xenopus Odf2 in multiciliated cell patterning and differentiation. Dev Biol. 2025 Apr;520:224-238. doi: 10.1016/j.ydbio.2025.01.014. Epub 2025 Jan 24. PMID: 39864486. |