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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12402 scientific papers returned from the database with the search filters currently being used below.
There are 12402 scientific papers returned from the database with the search filters currently being used below.
Formation of a “Pre-mouth Array” from the Extreme Anterior Domain Is Directed by Neural Crest and Wnt/PCP Signaling
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Citation:
Cell Rep. 2016;[Epub ahead of print] doi:10.1016/j.celrep.2016.06.073 Epub:
Yes Abstract:
The mouth arises from the extreme anterior domain (EAD), a region where the ectoderm and endoderm are directly juxtaposed. Here... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Jacox L, Chen J, Rothman A, Lathrop-Marshall H, Sive H. Formation of a “Pre-mouth Array” from the Extreme Anterior Domain Is Directed by Neural Crest and Wnt/PCP Signaling. Cell Rep. 2016;[Epub ahead of print] doi:10.1016/j.celrep.2016.06.073. |
Mutations in STN1 cause Coats plus syndrome and are associated with genomic and telomere defects
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Citation:
J Exp Med. 2016;[Epub ahead of print] doi:10.1084/jem.20151618 Epub:
Yes Abstract:
The analysis of individuals with telomere defects may shed light on the delicate interplay of factors controlling genome... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Simon AJ, Lev A, Zhang Y, Weiss B, Rylova A, Eyal E, Kol N, Bare O, Cesarkas K, Soudack M, Greenberg-Kushnir N, Rhodes M, Wiest DL, Schiby G, Barshack I, Katz S, Pras E, Poran H, Reznik-Wolf H, Ribakovsky E, Simon C, Hazou W, Sidi Y, Lahad A, Katzir H, Sagie S, Aqeilan HA, Glousker G, Amariglio N, Tzfati Y, Selig S, Rechavi G, Somech R. Mutations in STN1 cause Coats plus syndrome and are associated with genomic and telomere defects. J Exp Med. 2016;[Epub ahead of print] doi:10.1084/jem.20151618. |
Developmental Apoptosis Mediates Entry and Positioning of Microglia in the Zebrafish Brain
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Citation:
Cell Rep. 2016;16;1–10. doi:10.1016/j.celrep.2016.06.033 Epub:
Not Epub Abstract:
In the brain, neurons that fail to assemble into functional circuits are eliminated. Their clearance depends on microglia,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Casano AM, Albert M, Peri F. Developmental Apoptosis Mediates Entry and Positioning of Microglia in the Zebrafish Brain. Cell Rep. 2016;16;1–10. doi:10.1016/j.celrep.2016.06.033. |
ANKS3 is mutated in a family with autosomal recessive laterality defect
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Citation:
Hum Genet. 2016 Jul 14. [Epub ahead of print] Epub:
Yes Abstract:
Laterality defects are heterogeneous groups of congenital malformations that arise from perturbed asymmetrical development of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Shamseldin HE, Yakulov TA, Hashem A, Walz G, Alkuraya FS. ANKS3 is mutated in a family with autosomal recessive laterality defect. Hum Genet. 2016 Jul 14. [Epub ahead of print]. |
Rescue of neural crest derived phenotypes in a zebrafish CHARGE model by sox10 downregulation
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Citation:
Hum Mol Genet. 2016 Jul 13. pii: ddw198. [Epub ahead of print] Epub:
Yes Abstract:
CHD7 mutations are implicated in a majority of cases of the congenital disorder, CHARGE syndrome. CHARGE, an autosomal dominant... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Asad Z, Pandey A, Babu A, Sun Y, Shevade K, Kapoor S, Ullah I, Ranjan S, Scaria V, Bajpai R, Sachidanandan C. Rescue of neural crest derived phenotypes in a zebrafish CHARGE model by sox10 downregulation. Hum Mol Genet. 2016 Jul 13. pii: ddw198. [Epub ahead of print]. |
Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification
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Citation:
Nature. 2016;535:294-8. doi:10.1038/nature18614 Epub:
Not Epub Abstract:
Vascular and haematopoietic cells organize into specialized tissues during early embryogenesis to supply essential nutrients to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Reischauer S, Stone OA, Villasenor A, Chi N, Jin S-W, Martin M, Lee MT, Fukuda N, Marass M, Witty A, Fiddes I, Kuo T, Chung W-S, Salek S, Lerrigo R, Alsiö J, Luo S, Tworus D, Augustine SM, Mucenieks S, Nystedt B, Giraldez AJ, Schroth GP, Andersson O, Stainier DYR. Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification. Nature. 2016;535:294-8. doi:10.1038/nature18614. |
BMP and retinoic acid regulate anterior–posterior patterning of the non-axial mesoderm across the dorsal–ventral axis
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Citation:
Nat Comm. 2016;7:12197. doi:10.1038/ncomms12197 Epub:
Not Epub Abstract:
Despite the fundamental importance of patterning along the dorsal–ventral (DV) and anterior–posterior (AP) axes during... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Naylor RW, Skvarca LB, Thisse C, Thisse B, Hukriede NA, Davidson AJ. BMP and retinoic acid regulate anterior–posterior patterning of the non-axial mesoderm across the dorsal–ventral axis. Nat Comm. 2016;7:12197. doi:10.1038/ncomms12197. |
Germline replacement by blastula cell transplantation in the fish medaka
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Citation:
Sci Rep. 2016;6:29658. doi:10.1038/srep29658 Epub:
Not Epub Abstract:
Primordial germ cell (PGC) specification early in development establishes the germline for reproduction and reproductive... Delivery Method:
microinjection Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Li M, Hong N, Xu H, Song J, Yunhan Hong Y. Germline replacement by blastula cell transplantation in the fish medaka. Sci Rep. 2016;6:29658. doi:10.1038/srep29658. |
The Joubert Syndrome Protein Inpp5e Controls Ciliogenesis by Regulating Phosphoinositides at the Apical Membrane
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Citation:
J Am Soc Nephrol. 2016 Jul 8. pii: ASN.2015080906. [Epub ahead of print] Epub:
Yes Abstract:
Phosphoinositides, a family of phosphorylated derivatives of phosphatidylinositol (PtdIns), are tightly regulated both... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Xu W, Jin M, Hu R, Wang H, Zhang F, Yuan S, Cao Y. The Joubert Syndrome Protein Inpp5e Controls Ciliogenesis by Regulating Phosphoinositides at the Apical Membrane. J Am Soc Nephrol. 2016 Jul 8. pii: ASN.2015080906. [Epub ahead of print]. |
Optimization of Morpholino Antisense Oligonucleotides Targeting the Intronic Repressor Element1 in Spinal Muscular Atrophy
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Citation:
Mol Ther. 2016 Jul 12. doi: 10.1038/mt.2016.145. [Epub ahead of print] Epub:
Yes Abstract:
Loss of Survival Motor Neuron-1 (SMN1) causes Spinal Muscular Atrophy (SMA), a devastating neurodegenerative disease. SMN2 is a... Delivery Method:
Endo-Porter (cultures), icv (mice) Organism or Cell Type:
iPS-derived SMA motor neurons, mice Citation Extract: Osman EY, Washington CW 3rd, Kaifer KA, Mazzasette C, Patitucci TN, Florea KM, Simon ME, Ko CP, Ebert AD, Lorson CL. Optimization of Morpholino Antisense Oligonucleotides Targeting the Intronic Repressor Element1 in Spinal Muscular Atrophy. Mol Ther. 2016 Jul 12. doi: 10.1038/mt.2016.145. [Epub ahead of print]. |