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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12387 scientific papers returned from the database with the search filters currently being used below.

Efficient exon skipping of SGCG mutations mediated by phosphorodiamidate morpholino oligomers

Authors:
Wyatt EJ, Demonbreun AR, Kim EY, Puckelwartz MJ, Vo AH, Dellefave-Castillo LM, Gao QQ, Vainzof M, Pavanello RCM, Zatz M, McNally EM
Citation:
JCI Insight. 2018 May 3;3(9). pii: 99357. doi: 10.1172/jci.insight.99357. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Exon skipping uses chemically modified antisense oligonucleotides to modulate RNA splicing. Therapeutically, exon skipping can...
Link:
https://insight.jci.org/articles/view/99357
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: human primary fibroblasts differentiated to myogenic cells
Citation Extract:
Wyatt EJ, Demonbreun AR, Kim EY, Puckelwartz MJ, Vo AH, Dellefave-Castillo LM, Gao QQ, Vainzof M, Pavanello RCM, Zatz M, McNally EM. Efficient exon skipping of SGCG mutations mediated by phosphorodiamidate morpholino oligomers. JCI Insight. 2018 May 3;3(9). pii: 99357. doi: 10.1172/jci.insight.99357. [Epub ahead of print].

The Role of Palladin in Podocytes

Authors:
Artelt N, Ludwig TA, Rogge H, Kavvadas P, Siegerist F, Blumenthal A, van den Brandt J, Otey CA, Bang ML, Amann K, Chadjichristos CE, Chatziantoniou C, Endlich K, Endlich N
Citation:
J Am Soc Nephrol. 2018 May 2. pii: ASN.2017091039. doi: 10.1681/ASN.2017091039. [Epub ahead of print]
Epub:
Yes
Abstract:
Background: Podocyte loss and effacement of interdigitating podocyte foot processes are the major cause of a leaky filtration...
Link:
http://jasn.asnjournals.org/content/early/2018/05/01/ASN.2017091039.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Artelt N, Ludwig TA, Rogge H, Kavvadas P, Siegerist F, Blumenthal A, van den Brandt J, Otey CA, Bang ML, Amann K, Chadjichristos CE, Chatziantoniou C, Endlich K, Endlich N. The Role of Palladin in Podocytes. J Am Soc Nephrol. 2018 May 2. pii: ASN.2017091039. doi: 10.1681/ASN.2017091039. [Epub ahead of print].

let-7 MicroRNA-Mediated Regulation of Shh Signaling and the Gene Regulatory Network Is Essential for Retina Regeneration

Authors:
Kaur S, Gupta S, Chaudhary M, Khursheed MA, Mitra S, Kurup AJ, Ramachandran R
Citation:
Cell Rep. 2018;23(5):1409-23. doi:10.1016/j.celrep.2018.04.002
Epub:
Not Epub
Abstract:
Upon injury, Müller glia cells of the zebrafish retina reprogram themselves to progenitor cells with stem cell characteristics...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(18)30531-X
Delivery Method:
injection and electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Kaur S, Gupta S, Chaudhary M, Khursheed MA, Mitra S, Kurup AJ, Ramachandran R. let-7 MicroRNA-Mediated Regulation of Shh Signaling and the Gene Regulatory Network Is Essential for Retina Regeneration. Cell Rep. 2018;23(5):1409-23. doi:10.1016/j.celrep.2018.04.002.

Control of Pem protein level by localized maternal factors for transcriptional regulation in the germline of the ascidian, Halocynthia roretzi

Authors:
Miyaoku K, Nakamoto A, Nishida H, Kumano G
Citation:
PLoS ONE. 2018;13(4):e0196500. doi:10.1371/journal.pone.0196500
Epub:
Not Epub
Abstract:
Localized maternal mRNAs play important roles in embryogenesis, e.g. the establishment of embryonic axes and the developmental...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196500
Delivery Method:
microinjection
Organism or Cell Type:
Halocynthia roretzi
Citation Extract:
Miyaoku K, Nakamoto A, Nishida H, Kumano G. Control of Pem protein level by localized maternal factors for transcriptional regulation in the germline of the ascidian, Halocynthia roretzi. PLoS ONE. 2018;13(4):e0196500. doi:10.1371/journal.pone.0196500.

The left-right asymmetry of liver lobation is generated by Pitx2c-mediated asymmetries in the hepatic diverticulum

Authors:
Womble M, Amin NM, Nascone-Yoder N
Citation:
Dev Biol. 2018;[Epub] doi:10.1016/j.ydbio.2018.04.021
Epub:
Yes
Abstract:
Internal organs exhibit left-right asymmetric sizes, shapes and anatomical positions, but how these different lateralities...
Link:
https://www.sciencedirect.com/science/article/pii/S0012160617306759
Organism or Cell Type:
Xenopus
Citation Extract:
Womble M, Amin NM, Nascone-Yoder N. The left-right asymmetry of liver lobation is generated by Pitx2c-mediated asymmetries in the hepatic diverticulum. Dev Biol. 2018;[Epub] doi:10.1016/j.ydbio.2018.04.021.

Scaling up to study brca2: the zeppelin zebrafish mutant reveals a role for brca2 in embryonic development of kidney mesoderm

Authors:
Drummond BE, Wingert RA
Citation:
Cancer Cell Microenviron. 2018;5(1). pii: e1630. doi: 10.14800/ccm.1630. Epub 2018 Apr 9
Epub:
Not Epub
Abstract:
Specialized renal epithelial cells known as podocytes are essential components of the filtering structures within the kidney...
Link:
https://www.smartscitech.com/index.php/CCM/article/view/1630
Citation Extract:
Drummond BE, Wingert RA. Scaling up to study brca2: the zeppelin zebrafish mutant reveals a role for brca2 in embryonic development of kidney mesoderm. Cancer Cell Microenviron. 2018;5(1). pii: e1630. doi: 10.14800/ccm.1630. Epub 2018 Apr 9.

Functional enrichment analysis based on long noncoding RNA associations

Authors:
Hung K-S, Hsiao C-C, Pai T-W, Hu C-H, Tzou W-S, Wang W-D, Chen Y-R
Citation:
BMC Sys Biol. 2018;12(Suppl 4):45. doi:10.1186/s12918-018-0571-0
Epub:
Not Epub
Abstract:
Background: Differential gene expression analysis using RNA-seq data is a popular approach for discovering specific regulation...
Link:
https://bmcsystbiol.biomedcentral.com/articles/10.1186/s12918-018-0571-0
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hung K-S, Hsiao C-C, Pai T-W, Hu C-H, Tzou W-S, Wang W-D, Chen Y-R. Functional enrichment analysis based on long noncoding RNA associations. BMC Sys Biol. 2018;12(Suppl 4):45. doi:10.1186/s12918-018-0571-0.

Long ncRNA A-ROD activates its target gene DKK1 at its release from chromatin

Authors:
Ntini E, Louloupi A, Liz J, Muino JM, Marsico A, Ørom UAV
Citation:
Nat Commun. 2018 Apr 24;9(1):1636. doi: 10.1038/s41467-018-04100-3
Epub:
Not Epub
Abstract:
Long ncRNAs are often enriched in the nucleus and at chromatin, but whether their dissociation from chromatin is important for...
Link:
https://www.nature.com/articles/s41467-018-04100-3
Delivery Method:
Hiperfect (Qiagen)
Organism or Cell Type:
cell culture: MCF-7
Citation Extract:
Ntini E, Louloupi A, Liz J, Muino JM, Marsico A, Ørom UAV. Long ncRNA A-ROD activates its target gene DKK1 at its release from chromatin. Nat Commun. 2018 Apr 24;9(1):1636. doi: 10.1038/s41467-018-04100-3.

Brain Aromatase Modulates Serotonergic Neuron by Regulating Serotonin Levels in Zebrafish Embryos and Larvae

Authors:
Ulhaq ZS, Kishida M
Citation:
Front Endocrinol. 2018;[Epub] doi:10.3389/fendo.2018.00230
Epub:
Yes
Abstract:
Teleost fish are known to express two isoforms of P450aromatase, a key enzyme for estrogen synthesis. One of the isoforms,...
Link:
https://www.frontiersin.org/articles/10.3389/fendo.2018.00230/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ulhaq ZS, Kishida M. Brain Aromatase Modulates Serotonergic Neuron by Regulating Serotonin Levels in Zebrafish Embryos and Larvae. Front Endocrinol. 2018;[Epub] doi:10.3389/fendo.2018.00230.

Increased expression of amyloid precursor protein in oral squamous cell carcinoma

Authors:
Ko SY, Lin SC, Chang KW, Wong YK, Liu CJ, Chi CW, Liu TY
Citation:
Int J Cancer. 2004 Sep 20;111(5):727-32
Epub:
Not Epub
Abstract:
In our previous study, we identified amyloid precursor protein (APP) in an oral squamous cell carcinoma (OSCC)-enriching...
Link:
https://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.20328
Delivery Method:
cell scraping
Organism or Cell Type:
cell culture: OECM-1 and SCC25
Citation Extract:
Ko SY, Lin SC, Chang KW, Wong YK, Liu CJ, Chi CW, Liu TY. Increased expression of amyloid precursor protein in oral squamous cell carcinoma. Int J Cancer. 2004 Sep 20;111(5):727-32.

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