You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Functional role of pax6 in eye and central nervous system development in the annelid Capitella teleta

Authors:
Klann M, Seaver EC
Citation:
bioRxive. 2018;[preprint] doi:10.1101/481135
Epub:
Not Epub
Abstract:
The transcription factor Pax6 is an important regulator of early animal development. Loss of function mutations of pax6 in a...
Link:
https://www.biorxiv.org/content/early/2018/11/28/481135
Delivery Method:
microinjection
Organism or Cell Type:
Capitella teleta (annelid)
Citation Extract:
Klann M, Seaver EC. Functional role of pax6 in eye and central nervous system development in the annelid Capitella teleta. bioRxive. 2018;[preprint] doi:10.1101/481135.

Inflammasome-Mediated Regulation of Hematopoiesis in the Vertebrate Embryo

Authors:
Frame JM, Long T, Schuster-Kubaczka C, Esain V, Lim SE, Daley GQ, North T
Citation:
Blood. 2018;132:330. doi:10.1182/blood-2018-99-117076
Epub:
Not Epub
Abstract:
Hematopoietic stem and progenitor cells (HSPCs) arise in the embryonic dorsal aorta (DA) through a Runx1-dependent process of...
Link:
http://www.bloodjournal.org/content/132/Suppl_1/330
Organism or Cell Type:
zebrafish
Citation Extract:
Frame JM, Long T, Schuster-Kubaczka C, Esain V, Lim SE, Daley GQ, North T. Inflammasome-Mediated Regulation of Hematopoiesis in the Vertebrate Embryo. Blood. 2018;132:330. doi:10.1182/blood-2018-99-117076.

Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release

Authors:
Morioka S, Perry JSA, Raymond MH, Medina CB, Zhu Y, Zhao L, Serbulea V, Onengut-Gumuscu S, Leitinger N, Kucenas S, Rathmell JC, Makowski L, Ravichandran KS
Citation:
Nature. 2018 Nov 21. doi: 10.1038/s41586-018-0735-5. [Epub ahead of print]
Epub:
Yes
Abstract:
Development and routine tissue homeostasis require a high turnover of apoptotic cells. These cells are removed by professional...
Link:
https://www.nature.com/articles/s41586-018-0735-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Morioka S, Perry JSA, Raymond MH, Medina CB, Zhu Y, Zhao L, Serbulea V, Onengut-Gumuscu S, Leitinger N, Kucenas S, Rathmell JC, Makowski L, Ravichandran KS. Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release. Nature. 2018 Nov 21. doi: 10.1038/s41586-018-0735-5. [Epub ahead of print].

Maternal Huluwa dictates the embryonic body axis through β-catenin in vertebrates

Authors:
Yan L, Chen J, Zhu X, Sun J, Wu X, Shen W, Zhang W, Tao Q, Meng A
Citation:
Science. 2018;362(6417):eaat1045. doi:10.1126/science.aat1045
Epub:
Yes
Abstract:
The vertebrate body is formed by cell movements and shape change during embryogenesis. It remains undetermined which maternal...
Link:
http://science.sciencemag.org/content/362/6417/eaat1045
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Yan L, Chen J, Zhu X, Sun J, Wu X, Shen W, Zhang W, Tao Q, Meng A. Maternal Huluwa dictates the embryonic body axis through β-catenin in vertebrates. Science. 2018;362(6417):eaat1045. doi:10.1126/science.aat1045.

Conserved regulatory state expression controlled by divergent developmental gene regulatory networks in echinoids

Authors:
Erkenbrack EM, Davidson EH, Peter IS
Citation:
Development. 2018 Nov 23. pii: dev.167288. doi: 10.1242/dev.167288. [Epub ahead of print]
Epub:
Yes
Abstract:
Evolution of the animal body plan is driven by changes in developmental gene regulatory networks (GRNs), but how networks...
Link:
http://dev.biologists.org/content/early/2018/11/22/dev.167288.long
Organism or Cell Type:
Eucidaris tribuloides (sea urchin)
Citation Extract:
Erkenbrack EM, Davidson EH, Peter IS. Conserved regulatory state expression controlled by divergent developmental gene regulatory networks in echinoids. Development. 2018 Nov 23. pii: dev.167288. doi: 10.1242/dev.167288. [Epub ahead of print].

Induction of Interferon-Stimulated Genes and Cellular Stress Pathways by Morpholinos

Authors:
Lai JKH, Gagalova K, Stainier DYR
Citation:
bioRxive. 2018;[Preprint] doi:10.1101/479188
Epub:
Not Epub
Abstract:
The phenotypes caused by morpholino-mediated interference of gene function in zebrafish are often not observed in the...
Link:
https://www.biorxiv.org/content/early/2018/11/27/479188
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lai JKH, Gagalova K, Stainier DYR. Induction of Interferon-Stimulated Genes and Cellular Stress Pathways by Morpholinos. bioRxive. 2018;[Preprint] doi:10.1101/479188.

Centrosomal protein FOR20 is essential for cilia-dependent development in zebrafish embryos

Authors:
Xie S, Jin J, Xu Z, Huang Y, Zhang W, Zhao L, Lo LJ, Peng J, Liu W, Wang F, Shu Q, Zhou T
Citation:
FASEB J. 2018 Nov 26:fj201801235RR. doi: 10.1096/fj.201801235RR. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Centrosomal proteins play critical roles in ciliogenesis. Mutations in many centrosomal proteins have been documented to...
Link:
https://www.fasebj.org/doi/abs/10.1096/fj.201801235RR
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xie S, Jin J, Xu Z, Huang Y, Zhang W, Zhao L, Lo LJ, Peng J, Liu W, Wang F, Shu Q, Zhou T. Centrosomal protein FOR20 is essential for cilia-dependent development in zebrafish embryos. FASEB J. 2018 Nov 26:fj201801235RR. doi: 10.1096/fj.201801235RR. [Epub ahead of print].

Knockdown of calcium-binding calb2a and calb2b genes indicates the key regulator of the early development of the zebrafish, Danio rerio

Authors:
Bhoyar RC, Jadhao AG, Sabharwal A, Ranjan G, Sivasubbu S, Pinelli C
Citation:
Brain Struct Funct. 2018 Nov 20. doi: 10.1007/s00429-018-1797-8. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The present study initiates our investigation regarding the role of calb2a and calb2b genes that are expressed in the central...
Link:
https://link.springer.com/article/10.1007%2Fs00429-018-1797-8
Organism or Cell Type:
zebrafish
Citation Extract:
Bhoyar RC, Jadhao AG, Sabharwal A, Ranjan G, Sivasubbu S, Pinelli C. Knockdown of calcium-binding calb2a and calb2b genes indicates the key regulator of the early development of the zebrafish, Danio rerio. Brain Struct Funct. 2018 Nov 20. doi: 10.1007/s00429-018-1797-8. [Epub ahead of print].

Drug-free albumin-triggered sensitization of cancer cells to anticancer drugs

Authors:
Li L, Yang J, Soodvilai S, Wang J, Opanasopit P, Kopeček J
Citation:
J Control Release. 2018;[Epub ahead of print] doi:10.1016/j.jconrel.2018.11.015
Epub:
Yes
Abstract:
Chemosensitization strategies have been used to sensitize cancer cells to conventional drugs, but their utility is often...
Link:
https://www.sciencedirect.com/science/article/pii/S0168365918306527
Citation Extract:
Li L, Yang J, Soodvilai S, Wang J, Opanasopit P, Kopeček J. Drug-free albumin-triggered sensitization of cancer cells to anticancer drugs. J Control Release. 2018;[Epub ahead of print] doi:10.1016/j.jconrel.2018.11.015.

Exon Junction Complex Shapes the Transcriptome by Repressing Recursive Splicing

Authors:
Blazquez L, Emmett W, Faraway R, Pineda JMB, Bajew S, Gohr A, Haberman N, Sibley CR, Bradley RK, Irimia M, Ule J
Citation:
Mol Cell. 2018 Nov 1;72(3):496-509.e9. doi: 10.1016/j.molcel.2018.09.033
Epub:
Not Epub
Abstract:
Recursive splicing (RS) starts by defining an "RS-exon," which is then spliced to the preceding exon, thus creating a...
Link:
https://www.cell.com/molecular-cell/fulltext/S1097-2765(18)30832-3
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HeLa Flp-In T-REx KPNA1, mouse neural precursos cells (NPC)
Citation Extract:
Blazquez L, Emmett W, Faraway R, Pineda JMB, Bajew S, Gohr A, Haberman N, Sibley CR, Bradley RK, Irimia M, Ule J. Exon Junction Complex Shapes the Transcriptome by Repressing Recursive Splicing. Mol Cell. 2018 Nov 1;72(3):496-509.e9. doi: 10.1016/j.molcel.2018.09.033.

Pages