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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Transcriptomic profiles of tumor-associated neutrophils reveal prominent roles in enhancing angiogenesis in liver tumorigenesis in zebrafish

Authors:
Huo X, Li H, Li Z, Yan C, Agrawal I, Mathavan S, Liu J, Gong Z
Citation:
Sci Rep. 2019 Feb 6;9(1):1509. doi: 10.1038/s41598-018-36605-8
Epub:
Not Epub
Abstract:
We have previously demonstrated the pro-tumoral role of neutrophils using a kras-induced zebrafish hepatocarcinogenesis model....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Huo X, Li H, Li Z, Yan C, Agrawal I, Mathavan S, Liu J, Gong Z. Transcriptomic profiles of tumor-associated neutrophils reveal prominent roles in enhancing angiogenesis in liver tumorigenesis in zebrafish. Sci Rep. 2019 Feb 6;9(1):1509. doi: 10.1038/s41598-018-36605-8.

Mutation of microphthalmia-associated transcription factor (mitf) in zebrafish sensitizes for glomerulopathy

Authors:
Müller-Deile J, Schenk H, Niggemann P, Bolaños-Palmieri P, Teng B, Higgs A, Staggs L, Haller H, Schroder P, Schiffer M
Citation:
Biol Open. 2019 Feb 4. pii: bio.040253. doi: 10.1242/bio.040253. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Different glomerular diseases that affect podocyte homeostasis can clinically present as nephrotic syndrome with massive...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Müller-Deile J, Schenk H, Niggemann P, Bolaños-Palmieri P, Teng B, Higgs A, Staggs L, Haller H, Schroder P, Schiffer M. Mutation of microphthalmia-associated transcription factor (mitf) in zebrafish sensitizes for glomerulopathy. Biol Open. 2019 Feb 4. pii: bio.040253. doi: 10.1242/bio.040253. [Epub ahead of print].

Production of Germ-Line Chimeras in Zebrafish

Authors:
Saito T, Goto R, Rivers N, Yamaha E
Citation:
Methods Mol Biol. 2019;1920:327-341. doi: 10.1007/978-1-4939-9009-2_20
Epub:
Not Epub
Abstract:
The induction of germ-line chimerism in fish is a strategy for the reproduction of endangered or genetically valuable fish...
Organism or Cell Type:
zebrafish
Citation Extract:
Saito T, Goto R, Rivers N, Yamaha E. Production of Germ-Line Chimeras in Zebrafish. Methods Mol Biol. 2019;1920:327-341. doi: 10.1007/978-1-4939-9009-2_20.

Embryological and Genetic Manipulation of Chick Development

Authors:
Gammill LS, Jacques-Fricke B, Roffers-Agarwal J
Citation:
Methods Mol Biol. 2019;1920:75-97. doi: 10.1007/978-1-4939-9009-2_6
Epub:
Not Epub
Abstract:
The ability to combine embryological manipulations with gene function analysis in an amniote embryo makes the chick a valuable...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Gammill LS, Jacques-Fricke B, Roffers-Agarwal J. Embryological and Genetic Manipulation of Chick Development. Methods Mol Biol. 2019;1920:75-97. doi: 10.1007/978-1-4939-9009-2_6.

Transcriptome profiling of zebrafish optic fissure fusion

Authors:
Richardson R, Owen N, Toms M, Young RM, Tracey-White D, Moosajee M
Citation:
Sci Rep. 2019 Feb 7;9(1):1541. doi: 10.1038/s41598-018-38379-5
Epub:
Not Epub
Abstract:
Incomplete fusion of the optic fissure leads to ocular coloboma, a congenital eye defect that affects up to 7.5 per 10,000...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Richardson R, Owen N, Toms M, Young RM, Tracey-White D, Moosajee M. Transcriptome profiling of zebrafish optic fissure fusion. Sci Rep. 2019 Feb 7;9(1):1541. doi: 10.1038/s41598-018-38379-5.

The regulatory pathway from genes directly activated by maternal factors to muscle structural genes in ascidian embryos

Authors:
Yu D, Oda-Ishii I, Kubo A, Satou Y
Citation:
Development. 2019 Jan 23. pii: dev.173104. doi: 10.1242/dev.173104. [Epub ahead of print]
Epub:
Yes
Abstract:
Striated muscle cells in the tail of ascidian tadpole larvae differentiate cell-autonomously. Although several key regulatory...
Delivery Method:
microinjection
Organism or Cell Type:
ascidian
Citation Extract:
Yu D, Oda-Ishii I, Kubo A, Satou Y. The regulatory pathway from genes directly activated by maternal factors to muscle structural genes in ascidian embryos. Development. 2019 Jan 23. pii: dev.173104. doi: 10.1242/dev.173104. [Epub ahead of print].

A genetic model of CEDNIK syndrome in zebrafish highlights the role of the SNARE protein Snap29 in neuromotor and epidermal development

Authors:
Mastrodonato V, Beznoussenko G, Mironov A, Ferrari L, Deflorian G, Vaccari T
Citation:
Sci Rep. 2019:1211. doi:10.1038/s41598-018-37780-4
Epub:
Not Epub
Abstract:
Homozygous mutations in SNAP29, encoding a SNARE protein mainly involved in membrane fusion, cause CEDNIK (Cerebral Dysgenesis...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mastrodonato V, Beznoussenko G, Mironov A, Ferrari L, Deflorian G, Vaccari T. A genetic model of CEDNIK syndrome in zebrafish highlights the role of the SNARE protein Snap29 in neuromotor and epidermal development. Sci Rep. 2019:1211. doi:10.1038/s41598-018-37780-4.

Prickle1 is required for EMT and migration of zebrafish cranial neural crest

Authors:
Ahsan K, Singh N, Rocha M, Huang C, Prince VE
Citation:
Dev Biol. 2019;[Epub ahead of print] doi:10.1016/j.ydbio.2019.01.018
Epub:
Yes
Abstract:
The neural crest -- a key innovation of the vertebrates -- gives rise to diverse cell types including melanocytes, neurons and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ahsan K, Singh N, Rocha M, Huang C, Prince VE. Prickle1 is required for EMT and migration of zebrafish cranial neural crest. Dev Biol. 2019;[Epub ahead of print] doi:10.1016/j.ydbio.2019.01.018.

Biallelic KARS pathogenic variants cause an early-onset progressive leukodystrophy

Authors:
Itoh M, Dai H, Horike SI, Gonzalez J, Kitami Y, Meguro-Horike M, Kuki I, Shimakawa S, Yoshinaga H, Ota Y, Okazaki T, Maegaki Y, Nabatame S, Okazaki S, Kawawaki H, Ueno N, Goto YI, Kato Y
Citation:
Brain. 2019 Feb 3. doi: 10.1093/brain/awz001. [Epub ahead of print]
Epub:
Yes
Abstract:
The leukodystrophies cause severe neurodevelopmental defects from birth and follow an incurable and progressive course that...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Itoh M, Dai H, Horike SI, Gonzalez J, Kitami Y, Meguro-Horike M, Kuki I, Shimakawa S, Yoshinaga H, Ota Y, Okazaki T, Maegaki Y, Nabatame S, Okazaki S, Kawawaki H, Ueno N, Goto YI, Kato Y. Biallelic KARS pathogenic variants cause an early-onset progressive leukodystrophy. Brain. 2019 Feb 3. doi: 10.1093/brain/awz001. [Epub ahead of print].

AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate

Authors:
Gu Q, Yang X, Lv J, Zhang J, Xia B, Kim JD, Wang R, Xiong F, Meng S, Clements TP, Tandon B, Wagner DS, Diaz MF, Wenzel PL, Miller YI, Traver D, Cooke JP, Li W, Zon LI, Chen K, Bai Y, Fang L
Citation:
Science. 2019 Jan 31. pii: eaav1749. doi: 10.1126/science.aav1749. [Epub ahead of print]
Epub:
Yes
Abstract:
Hypercholesterolemia, the driving force of atherosclerosis, accelerates the expansion and mobilization of hematopoietic stem...
Citation Extract:
Gu Q, Yang X, Lv J, Zhang J, Xia B, Kim JD, Wang R, Xiong F, Meng S, Clements TP, Tandon B, Wagner DS, Diaz MF, Wenzel PL, Miller YI, Traver D, Cooke JP, Li W, Zon LI, Chen K, Bai Y, Fang L. AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate. Science. 2019 Jan 31. pii: eaav1749. doi: 10.1126/science.aav1749. [Epub ahead of print].

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