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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

The Paf1 Complex and P-TEFb have reciprocal and antagonist roles in maintaining multipotent neural crest progenitors

Authors:
Jurynec MJ, Bai X, Bisgrove BW, Jackson H, Nechiporuk A, Palu RAS, Grunwald HA, Su YC, Hoshijima K, Yost HJ, Zon LI, Grunwald DJ
Citation:
Development. 2019 Nov 29. pii: dev.180133. doi: 10.1242/dev.180133. [Epub ahead of print]
Epub:
Yes
Abstract:
Multipotent progenitor populations are necessary for generating diverse tissue types during embryogenesis. We show the...
Link:
https://dev.biologists.org/content/early/2019/11/25/dev.180133
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jurynec MJ, Bai X, Bisgrove BW, Jackson H, Nechiporuk A, Palu RAS, Grunwald HA, Su YC, Hoshijima K, Yost HJ, Zon LI, Grunwald DJ. The Paf1 Complex and P-TEFb have reciprocal and antagonist roles in maintaining multipotent neural crest progenitors. Development. 2019 Nov 29. pii: dev.180133. doi: 10.1242/dev.180133. [Epub ahead of print].

Exon-Mediated Activation of Transcription Starts

Authors:
Fiszbein A, Krick KS, Begg BE, Burge CB
Citation:
Cell. 2019;[epub ahead of print] doi:10.1016/j.cell.2019.11.002
Epub:
Yes
Abstract:
The processing of RNA transcripts from mammalian genes occurs in proximity to their transcription. Here, we describe a...
Link:
https://www.cell.com/cell/pdf/S0092-8674(19)31223-1.pdf
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: mouse fibroblasts
Citation Extract:
Fiszbein A, Krick KS, Begg BE, Burge CB. Exon-Mediated Activation of Transcription Starts. Cell. 2019;[epub ahead of print] doi:10.1016/j.cell.2019.11.002.

Chemokine-biased robust self-organizing polarization of migrating cells in vivo

Authors:
Olguin-Olguin A, Aalto A, Maugis B, Reichman-Fried M, Raz E
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/857623
Epub:
Not Epub
Abstract:
The mechanisms facilitating the establishment of front-rear polarity in migrating cells are not fully understood, in particular...
Link:
https://www.biorxiv.org/content/10.1101/857623v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Olguin-Olguin A, Aalto A, Maugis B, Reichman-Fried M, Raz E. Chemokine-biased robust self-organizing polarization of migrating cells in vivo. bioRxiv. 2019;[preprint] doi:10.1101/857623.

Whole-Exome Sequencing Identifies Damaging de novo Variants in Anencephalic Cases

Authors:
Wang L, Ren A, Tian T, Li N, Cao X, Zhang P, Jin L, Li Z, Shen Y, Zhang B, Finnell RH, Lei Y
Citation:
Front Neurosci. 2019;13:1285. doi:10.3389/fnins.2019.01285
Epub:
Not Epub
Abstract:
Background: Anencephaly is a lethal neural tube defect (NTD). Although variants in several genes have been implicated in the...
Link:
https://www.frontiersin.org/articles/10.3389/fnins.2019.01285/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang L, Ren A, Tian T, Li N, Cao X, Zhang P, Jin L, Li Z, Shen Y, Zhang B, Finnell RH, Lei Y. Whole-Exome Sequencing Identifies Damaging de novo Variants in Anencephalic Cases. Front Neurosci. 2019;13:1285. doi:10.3389/fnins.2019.01285.

Effects of spinetoram on the developmental toxicity and immunotoxicity of zebrafish

Authors:
Cheng B, Zhang H, Jia K, Li E, Zhang S, Yu H, Cao Z, Xiong G, Hu C, Lu H
Citation:
Fish Shellfish Immunol. 2019 Nov 28. pii: S1050-4648(19)31109-X. doi: 10.1016/j.fsi.2019.11.066. [Epub ahead of print]
Epub:
Yes
Abstract:
Our study investigated the effects of spinetoram on the developmental toxicity and immunotoxicity of zebrafish. 10 h post-...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S105046481931109X
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cheng B, Zhang H, Jia K, Li E, Zhang S, Yu H, Cao Z, Xiong G, Hu C, Lu H. Effects of spinetoram on the developmental toxicity and immunotoxicity of zebrafish. Fish Shellfish Immunol. 2019 Nov 28. pii: S1050-4648(19)31109-X. doi: 10.1016/j.fsi.2019.11.066. [Epub ahead of print].

Modulation of RECK levels in Xenopus A6 cells: effects on MT1-MMP, MMP-2 and pERK levels

Authors:
Willson JA, Bork BS, Muir CA, Damjanovski S
Citation:
J Biol Res (Thessaloniki). 2019;26:16. doi:10.1186/s40709-019-0108-8
Epub:
Not Epub
Abstract:
Background: MT1-MMP is a cell-surface enzyme whose regulation of pro-MMP-2 and ERK activation position it as a key facilitator...
Link:
https://link.springer.com/article/10.1186%2Fs40709-019-0108-8
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: Xenopus A6 cells
Citation Extract:
Willson JA, Bork BS, Muir CA, Damjanovski S. Modulation of RECK levels in Xenopus A6 cells: effects on MT1-MMP, MMP-2 and pERK levels. J Biol Res (Thessaloniki). 2019;26:16. doi:10.1186/s40709-019-0108-8.

Dkk1 Controls Cell-Cell Interaction through Regulation of Non-nuclear β-Catenin Pools

Authors:
Johansson M, Giger FA, Fielding T, Houart C
Citation:
Dev Cell. 2019 Nov 26. pii: S1534-5807(19)30904-9. doi: 10.1016/j.devcel.2019.10.026. [Epub ahead of print]
Epub:
Yes
Abstract:
Dickkopf-1 (Dkk1) is a secreted Wnt antagonist with a well-established role in head induction during development. Numerous...
Link:
https://www.sciencedirect.com/science/article/pii/S1534580719309049
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Johansson M, Giger FA, Fielding T, Houart C. Dkk1 Controls Cell-Cell Interaction through Regulation of Non-nuclear β-Catenin Pools. Dev Cell. 2019 Nov 26. pii: S1534-5807(19)30904-9. doi: 10.1016/j.devcel.2019.10.026. [Epub ahead of print].

Characterizing renal involvement in Hermansky-Pudlak Syndrome in a zebrafish model

Authors:
Schenk H, Müller-Deile J, Schroder P, Bolaños-Palmieri P, Beverly-Staggs L, White R, Bräsen JH, Haller H, Schiffer M
Citation:
Sci Rep. 2019 Nov 27;9(1):17718. doi: 10.1038/s41598-019-54058-5
Epub:
Not Epub
Abstract:
Hermansky-Pudlak Syndrome (HPS) is a rare disease caused by mutations in the genes coding for various HPS proteins. HPS...
Link:
https://www.nature.com/articles/s41598-019-54058-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schenk H, Müller-Deile J, Schroder P, Bolaños-Palmieri P, Beverly-Staggs L, White R, Bräsen JH, Haller H, Schiffer M. Characterizing renal involvement in Hermansky-Pudlak Syndrome in a zebrafish model. Sci Rep. 2019 Nov 27;9(1):17718. doi: 10.1038/s41598-019-54058-5.

Embryo microinjection of the lecithotrophic sea urchin Heliocidaris erythrogramma

Authors:
Edgar A, Byrne M, Wray GA
Citation:
J Biol Methods. 2019 Sep 17;6(3):e119. doi: 10.14440/jbm.2019.292. eCollection 2019
Epub:
Not Epub
Abstract:
Microinjection is a common embryological technique used for many types of experiments, including lineage tracing, manipulating...
Link:
http://www.jbmethods.org/jbm/article/view/292
Delivery Method:
microinjection
Organism or Cell Type:
Heliocidaris erythrogramma (sea urchin)
Citation Extract:
Edgar A, Byrne M, Wray GA. Embryo microinjection of the lecithotrophic sea urchin Heliocidaris erythrogramma. J Biol Methods. 2019 Sep 17;6(3):e119. doi: 10.14440/jbm.2019.292. eCollection 2019.

PDGF signaling from pharyngeal pouches promotes arch artery morphogenesis

Authors:
Mao A, Zhang M, Liu J, Cao Y, Wang Q
Citation:
J Genet Genom. 2019;[epub ahead of print] doi:10.1016/j.jgg.2019.11.004
Epub:
Yes
Abstract:
The great vessels of the heart originate from the pharyngeal arch arteries (PAAs). Anomalies of the PAAs often occur together...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S1673852719301778
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mao A, Zhang M, Liu J, Cao Y, Wang Q. PDGF signaling from pharyngeal pouches promotes arch artery morphogenesis. J Genet Genom. 2019;[epub ahead of print] doi:10.1016/j.jgg.2019.11.004.

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