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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Antisense oligonucleotide-based treatment of retinitis pigmentosa caused by USH2A exon 13 mutations
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.10.06.320499 Epub:
Not Epub Abstract:
Mutations in USH2A, encoding usherin, are the most common cause of syndromic and non-syndromic retinitis pigmentosa (RP). The... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Slijkerman R, van Diepen H, Dona M, Venselaar H, Zang J, Neuhauss S, Peters T, Broekman S, Pennings R, Kremer H, Adamson P, de Vrieze E, van Wijk E. Antisense oligonucleotide-based treatment of retinitis pigmentosa caused by USH2A exon 13 mutations. bioRxiv. 2020;[preprint] doi:10.1101/2020.10.06.320499 . |
Kctd15 regulates nephron segment development by repressing Tfap2a activity
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Citation:
Development. 2020;147:dev191973 doi:10.1242/dev.191973 Epub:
Not Epub Abstract:
A functional vertebrate kidney relies on structural units called nephrons, which are epithelial tubules with a sequence of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chambers BE, Clark EG, Gatz AE, Wingert RA. Kctd15 regulates nephron segment development by repressing Tfap2a activity. Development. 2020;147:dev191973 doi:10.1242/dev.191973. |
Eomesodermin is functionally conserved between zebrafish and mouse in spite of different mutant phenotypic severities, and controls left/right organiser formation via interlocking feedforward loops
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.10.02.324244 Epub:
Not Epub Abstract:
The T-box family transcription factor Eomesodermin (Eomes) is present in all vertebrates, with many key roles in the developing... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Talbot CD, Walsh MD, Cutty SJ, Elsayed R, Bruce AEE, Wardle FC, Nelson AC. Eomesodermin is functionally conserved between zebrafish and mouse in spite of different mutant phenotypic severities, and controls left/right organiser formation via interlocking feedforward loops. bioRxiv. 2020;[preprint] doi:10.1101/2020.10.02.324244 . |
Hcfc1b, a zebrafish ortholog of HCFC1, regulates craniofacial development by modulating mmachc expression
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Citation:
Dev Biol. 2014 Dec 1;396(1):94-106. doi: 10.1016/j.ydbio.2014.09.026. Epub 2014 Oct 2 Epub:
Not Epub Abstract:
Mutations in HCFC1 (MIM300019), have been recently associated with cblX (MIM309541), an X-linked, recessive disorder... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Quintana AM, Geiger EA, Achilly N, Rosenblatt DS, Maclean KN, Stabler SP, Artinger KB, Appel B, Shaikh TH. Hcfc1b, a zebrafish ortholog of HCFC1, regulates craniofacial development by modulating mmachc expression. Dev Biol. 2014 Dec 1;396(1):94-106. doi: 10.1016/j.ydbio.2014.09.026. Epub 2014 Oct 2. |
Caveolin 1 is required for axonal outgrowth of motor neurons and affects Xenopus neuromuscular development
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Citation:
Sci Rep. 2020 Oct 5;10(1):16446. doi: 10.1038/s41598-020-73429-x Epub:
Not Epub Abstract:
Caveolins are essential structural proteins driving the formation of caveolae, specialized invaginations of the plasma membrane... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Breuer M, Berger H, Borchers A. Caveolin 1 is required for axonal outgrowth of motor neurons and affects Xenopus neuromuscular development. Sci Rep. 2020 Oct 5;10(1):16446. doi: 10.1038/s41598-020-73429-x. |
Extrahypothalamic oxytocin neurons drive stress-induced social vigilance and avoidance
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Citation:
Proc Natl Acad Sci U S A. 2020 Oct 5:202011890. doi: 10.1073/pnas.2011890117. Online ahead of print Epub:
Yes Abstract:
Oxytocin increases the salience of both positive and negative social contexts and it is thought that these diverse actions on... Delivery Method:
medioventral bed nucleus of the stria terminalis (BNSTmv) Vivo-Morpholino injection Organism or Cell Type:
Peromyscus californicus (California mice) Citation Extract: Duque-Wilckens N, Torres LY, Yokoyama S, Minie VA, Tran AM, Petkova SP, Hao R, Ramos-Maciel S, Rios RA, Jackson K, Flores-Ramirez FJ, Garcia-Carachure I, Pesavento PA, Iñiguez SD, Grinevich V, Trainor BC. Extrahypothalamic oxytocin neurons drive stress-induced social vigilance and avoidance. Proc Natl Acad Sci U S A. 2020 Oct 5:202011890. doi: 10.1073/pnas.2011890117. Online ahead of print. |
An adhesion code ensures robust pattern formation during tissue morphogenesis
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Citation:
Science. 2020:370(6512):113-6. doi:10.1126/science.aba6637 Epub:
Not Epub Abstract:
Animal development entails the organization of specific cell types in space and time, and spatial patterns must form in a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tsai TY-C, Sikora M, Xia P, Colak-Champollion T, Holger Knaut H, Heisenberg CP, Megason SG. An adhesion code ensures robust pattern formation during tissue morphogenesis. Science. 2020:370(6512):113-6. doi:10.1126/science.aba6637. |
c-Abl Tyrosine Kinase Is Regulated Downstream of the Cytoskeletal Protein Synemin in Head and Neck Squamous Cell Carcinoma Radioresistance and DNA Repair
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Citation:
Int J Molec Sci. 2020;21(9):7277. doi:10.3390/ijms21197277 Epub:
Not Epub Abstract:
The intermediate filament synemin has been previously identified as novel regulator of cancer cell therapy resistance and DNA... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Deville SS, Silva LFD, Vehlow A, Cordes N
. c-Abl Tyrosine Kinase Is Regulated Downstream of the Cytoskeletal Protein Synemin in Head and Neck Squamous Cell Carcinoma Radioresistance and DNA Repair. Int J Molec Sci. 2020;21(9):7277. doi:10.3390/ijms21197277. |
Gene regulatory networks controlling vertebrate retinal regeneration
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Citation:
Science. 2020;360(6519):eabb8598 doi:10.1126/science.abb8598 Epub:
Not Epub Abstract:
Injury induces retinal Müller glia of certain cold-blooded vertebrates, but not mammals, to regenerate neurons. To identify... Delivery Method:
electroporation Organism or Cell Type:
zebrafish Citation Extract: Hoang T, Wang J, Boyd P, Wang F, Santiago C, Jiang L, Yoo S, Lahne M, Todd LJ, Jia M, Saez C, Keuthan C, Palazzo I, Squires N, Campbell WA, Rajaii F, Parayil T, Trinh V, Kim DW, Wang G, Campbell LJ, Ash J, Fischer AJ, Hyde DR, Qian J, Blackshaw S. Gene regulatory networks controlling vertebrate retinal regeneration. Science. 2020;360(6519):eabb8598 doi:10.1126/science.abb8598. |
The flow responsive transcription factor Klf2 is required for myocardial wall integrity by modulating Fgf signaling
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Citation:
eLife. 2018:7:e38889 doi:10.7554/eLife.38889 Epub:
Not Epub Abstract:
Complex interplay between cardiac tissues is crucial for their integrity. The flow responsive transcription factor KLF2, which... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rasouli SJ, El-Brolosy M, Tsedeke AT, Bensimon-Brito A, Ghanbari P, Maischein H-M, Kuenne C, Stainier DY. The flow responsive transcription factor Klf2 is required for myocardial wall integrity by modulating Fgf signaling. eLife. 2018:7:e38889 doi:10.7554/eLife.38889. |