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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
A single-cell resolution developmental atlas of hematopoietic stem and progenitor cell expansion in zebrafish
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Citation:
Proc Nat Acad Sci USA. 2021;118(14):e2015748118. doi:10.1073/pnas.2015748118 Epub:
Not Epub Abstract:
During vertebrate embryogenesis, fetal hematopoietic stem and progenitor cells (HSPCs) exhibit expansion and differentiation... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Xia J, Kang Z, Xue Y, Ding Y, Gao S, Zhang Y, Lv P, Wang X, Ma D, Wang L, Han J-DJ, Liu F. A single-cell resolution developmental atlas of hematopoietic stem and progenitor cell expansion in zebrafish. Proc Nat Acad Sci USA. 2021;118(14):e2015748118. doi:10.1073/pnas.2015748118. |
Role of epigenetic m6A RNA methylation in vascular development: mettl3 regulates vascular development through PHLPP2/mTOR‐AKT signaling
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Citation:
FASEB J. 2021;[Epub] doi:10.1096/fj.202000516RR Epub:
Yes Abstract:
N6‐methyladenosine (m6A) methylation is the most prevalent RNA modification, and it emerges as an important regulatory... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Parial R, Li H, Li J, Archacki S, Yang Z, Wang IZ, Chen Q, Xu C, Wang QK. Role of epigenetic m6A RNA methylation in vascular development: mettl3 regulates vascular development through PHLPP2/mTOR‐AKT signaling. FASEB J. 2021;[Epub] doi:10.1096/fj.202000516RR. |
A polo-like kinase modulates cytokinesis and flagella biogenesis in Giardia lamblia
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Citation:
Parasit Vectors. 2021;14:182. doi:10.1186/s13071-021-04687-5 Epub:
Not Epub Abstract:
Background: Polo-like kinases (PLKs) are conserved serine/threonine kinases that regulate the cell cycle. To date, the role of... Delivery Method:
electroporation Organism or Cell Type:
Giardia lamblia Citation Extract: Park EA, Kim J, Shin MY, Park S-J. A polo-like kinase modulates cytokinesis and flagella biogenesis in Giardia lamblia. Parasit Vectors. 2021;14:182. doi:10.1186/s13071-021-04687-5. |
Rapid and Unamplified Identification of COVID-19 with Morpholino-Modified Graphene Field-Effect Transistor Nanosensor
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Citation:
Biosens Bioelectron. 2021;[Epub] doi:10.1016/j.bios.2021.113206 Epub:
Yes Abstract:
SARS-CoV-2 RNA is identified as a pivotal player to bolster energizing zones of COVID-19 detection. Herein, we develop a rapid... Citation Extract: Li J, Wu D, Yu Y, Li T, Li K, Xiao M-M, Li Y, Zhang Z-Y, Zhang G-J. Rapid and Unamplified Identification of COVID-19 with Morpholino-Modified Graphene Field-Effect Transistor Nanosensor. Biosens Bioelectron. 2021;[Epub] doi:10.1016/j.bios.2021.113206. |
NOX5 is Expressed Aberrantly but Not a Critical Pathogenetic Gene in Hirschsprung Disease
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Citation:
BMC Pediatr. 2021;15:123 doi:10.1186/s12887-021-02611-5 Epub:
Not Epub Abstract:
Background: Hirschsprung disease (HSCR) is a congenital disorder characterized by the absence of intramural ganglion cells in... Citation Extract: Wang J, Xiao J, Meng X, Chu X, Zhuansun DD, Xiong B, Feng J. NOX5 is Expressed Aberrantly but Not a Critical Pathogenetic Gene in Hirschsprung Disease. BMC Pediatr. 2021;15:123 doi:10.1186/s12887-021-02611-5. |
Analysis of Chd-7 Defective Dauer Nematodes Implicates Collagen Misregulation in Charge Syndrome Features
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.03.26.437191 Epub:
Not Epub Abstract:
CHARGE syndrome is a complex developmental disorder caused by mutations in the chromodomain helicase DNA-binding protein7 (CHD7... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Jofré DM, Hoffman DK, Cervino AS, Grundy M, Yun S, Amrit FRG, Stolz DB, Salvatore E, Rossi FA, Ghazi A, Cirio MC, Yanowitz JL, Hochbaum D. Analysis of Chd-7 Defective Dauer Nematodes Implicates Collagen Misregulation in Charge Syndrome Features. bioRxiv. 2021;[preprint] doi:10.1101/2021.03.26.437191. |
UXT chaperone prevents proteotoxicity by acting as an autophagy adaptor for p62-dependent aggrephagy
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Citation:
Nat Commun. 2021;12(1):1955. doi:10.1038/s41467-021-22252-7 Epub:
Not Epub Abstract:
p62/SQSTM1 is known to act as a key mediator in the selective autophagy of protein aggregates, or aggrephagy, by steering... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Yoon MJ, Choi B, Kim EJ, Ohk J, Yang C, Choi Y-G, Lee J, Kang C, Song HK, Kim YK, Woo J-S, Cho Y, Choi E-J, Jung H, Kim C. UXT chaperone prevents proteotoxicity by acting as an autophagy adaptor for p62-dependent aggrephagy. Nat Commun. 2021;12(1):1955. doi:10.1038/s41467-021-22252-7. |
Proof-of-Concept: Antisense Oligonucleotide Mediated Skipping of Fibrillin-1 Exon 52
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Citation:
Int J Mol Sci. 2021;22(7):3479. doi:10.3390/ijms22073479 Epub:
Not Epub Abstract:
Marfan syndrome is one of the most common dominantly inherited connective tissue disorders, affecting 2–3 in 10,000 individuals... Delivery Method:
electroporation Organism or Cell Type:
cell culture: primary Marfan fibroblasts Citation Extract: Cale JM, Greer K, Fletcher S, Wilton SD. Proof-of-Concept: Antisense Oligonucleotide Mediated Skipping of Fibrillin-1 Exon 52. Int J Mol Sci. 2021;22(7):3479. doi:10.3390/ijms22073479. |
RNA demethylation by FTO stabilizes the FOXJ1 mRNA for proper motile ciliogenesis
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Citation:
Dev Cell. 2021 Mar 16:S1534-5807(21)00203-3. doi: 10.1016/j.devcel.2021.03.006. Online ahead of print Epub:
Not Epub Abstract:
Adenosine N6-methylation (m6A) is one of the most pervasive mRNA modifications, and yet the physiological significance of m6A... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Kim H, Lee YS, Kim SM, Jang S, Choi H, Lee JW, Kim TD, Kim VN. RNA demethylation by FTO stabilizes the FOXJ1 mRNA for proper motile ciliogenesis. Dev Cell. 2021 Mar 16:S1534-5807(21)00203-3. doi: 10.1016/j.devcel.2021.03.006. Online ahead of print. |
A conserved role for the ALS-linked splicing factor SFPQ in repression of pathogenic cryptic last exon
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Citation:
Nat Comm. 2021;12(1):1918. doi:10.1038/s41467-021-22098-z Epub:
Not Epub Abstract:
The RNA-binding protein SFPQ plays an important role in neuronal development and has been associated with several... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gordon PM, Hamid F, Makeyev EV, Houart C. A conserved role for the ALS-linked splicing factor SFPQ in repression of pathogenic cryptic last exon. Nat Comm. 2021;12(1):1918. doi:10.1038/s41467-021-22098-z. |