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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

The cytokine FAM3B/PANDER is an FGFR ligand that promotes posterior development in Xenopus

Authors:
Zhang F, Zhu X, Wang P, He Q, Huang H, Zheng T, Li Y, Jia H, Xu L, Zhao H, Colozza G, Tao Q, De Robertis EM, Ding Y
Citation:
Proc Nat Acad Sci USA. 2021;118(20):e2100342118. doi:10.1073/pnas.2100342118
Epub:
Not Epub
Abstract:
Fibroblast growth factor (FGF)/extracellular signal-regulated kinase (ERK) signaling plays a crucial role in anterior–posterior...
Link:
https://www.pnas.org/content/118/20/e2100342118
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Zhang F, Zhu X, Wang P, He Q, Huang H, Zheng T, Li Y, Jia H, Xu L, Zhao H, Colozza G, Tao Q, De Robertis EM, Ding Y. The cytokine FAM3B/PANDER is an FGFR ligand that promotes posterior development in Xenopus. Proc Nat Acad Sci USA. 2021;118(20):e2100342118. doi:10.1073/pnas.2100342118.

High-resolution mapping of the period landscape reveals polymorphism in cell cycle frequency tuning

Authors:
Li Z, Wang S, Sun M, Jin M, Khain D, Yang Q
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.10.442602
Epub:
Not Epub
Abstract:
Many biological oscillators exhibit widely tunable frequency in adapting to environmental changes. Although theoretical studies...
Link:
https://www.biorxiv.org/content/10.1101/2021.05.10.442602v1
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Li Z, Wang S, Sun M, Jin M, Khain D, Yang Q. High-resolution mapping of the period landscape reveals polymorphism in cell cycle frequency tuning. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.10.442602 .

RNA m6A methyltransferase Mettl3 regulates spatial neural patterning in Xenopus

Authors:
Kim H, Jang S
Citation:
Mol Cell Biol. 2021 May 10:MCB.00104-21. doi: 10.1128/MCB.00104-21. Online ahead of print
Epub:
Yes
Abstract:
N6-methyladenosine (m6A) is the most prevalent internal RNA modification, and has a widespread impact on mRNA stability and...
Link:
https://mcb.asm.org/content/early/2021/05/04/MCB.00104-21
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Kim H, Jang S. RNA m6A methyltransferase Mettl3 regulates spatial neural patterning in Xenopus. Mol Cell Biol. 2021 May 10:MCB.00104-21. doi: 10.1128/MCB.00104-21. Online ahead of print.

Cardioluminescence in transgenic zebrafish embryos: a Ca2+ imaging tool to study drug effects and pathological modeling

Authors:
Vicente M, Salgado-Almario J, Collins MM, Martínez-Sielva A, Minoshima M, Kikuchi K, Domingo B, Llopis J
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.06.442917
Epub:
Not Epub
Abstract:
The zebrafish embryo has emerged as an excellent model in cardiovascular research. The existing techniques to monitor Ca2+ in...
Link:
https://www.biorxiv.org/content/10.1101/2021.05.06.442917v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Vicente M, Salgado-Almario J, Collins MM, Martínez-Sielva A, Minoshima M, Kikuchi K, Domingo B, Llopis J. Cardioluminescence in transgenic zebrafish embryos: a Ca2+ imaging tool to study drug effects and pathological modeling. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.06.442917.

Biallelic variants in HPDL cause pure and complicated hereditary spastic paraplegia

Authors:
Wiessner M, Maroofian R, Ni M-Y, Pedroni A, Müller JS, Stucka R, Beetz C, Efthymiou S, Santorelli FM, Alfares AA, Zhu C, Uhrova MA, Alehabib E, Bakhtiari S, Janecke AR, Otero MG, Chen JYH, Peterson JT, Strom TM, De JP, Deconinck T, De Ridder W, De Winter J, Pasquariello R, Ricca I,Alfadhel M, van de Warrenburg BP, Portier R, Bergmann C, Ghasemi FS,Jin SC, Bilguvar K, Hamed S, Abdelhameed M, Haridy NA, Maqbool S, Rahman F, Anwar N, Carmichael J, Pagnamenta A, Wood NW, Tran Mau-Them F, Haack T, Genomics England Research Consortium PREPARE network, Di Rocco M, <authors deleted - database limit> Shamseldin H, Al Tala S, Rezazadeh VJ, Najafi M, Deschner S, Gläser D, Hüttel W, Kruer MC, Kamsteeg E-J, Takiyama Y, Züchner S, Baets J, Synofzik M, Schüle R, Horvath R, Houlden H, Bartesaghi L, Lee H-J, Ampatzis K, Pierson TM, Senderek J
Citation:
Brain. 2021;[Epub] doi:10.1093/brain/awab041
Epub:
Not Epub
Abstract:
Human 4-hydroxyphenylpyruvate dioxygenase-like (HPDL) is a putative iron-containing non-heme oxygenase of unknown specificity...
Link:
https://academic.oup.com/brain/advance-article-abstract/doi/10.1093/brain/awab041/6273093
Organism or Cell Type:
zebrafish
Citation Extract:
Wiessner M, Maroofian R, Ni M-Y, Pedroni A, Müller JS, Stucka R, Beetz C, Efthymiou S, Santorelli FM, Alfares AA, Zhu C, Uhrova MA, Alehabib E, Bakhtiari S, Janecke AR, Otero MG, Chen JYH, Peterson JT, Strom TM, De JP, Deconinck T, De Ridder W, De Winter J, Pasquariello R, Ricca I,Alfadhel M, van de Warrenburg BP, Portier R, Bergmann C, Ghasemi FS,Jin SC, Bilguvar K, Hamed S, Abdelhameed M, Haridy NA, Maqbool S, Rahman F, Anwar N, Carmichael J, Pagnamenta A, Wood NW, Tran Mau-Them F, Haack T, Genomics England Research Consortium PREPARE network, Di Rocco M, <authors deleted - database limit> Shamseldin H, Al Tala S, Rezazadeh VJ, Najafi M, Deschner S, Gläser D, Hüttel W, Kruer MC, Kamsteeg E-J, Takiyama Y, Züchner S, Baets J, Synofzik M, Schüle R, Horvath R, Houlden H, Bartesaghi L, Lee H-J, Ampatzis K, Pierson TM, Senderek J. Biallelic variants in HPDL cause pure and complicated hereditary spastic paraplegia. Brain. 2021;[Epub] doi:10.1093/brain/awab041.

RNA toxicity and perturbation of rRNA processing in spinocerebellar ataxia type 2

Authors:
Li PP, Moulick R, Feng H, Sun X, Arbez N, Jin J, Marque LO, Hedglen E, Chan HYE, Ross CA, Pulst SM, Margolis RL, Woodson S, Rudnicki DD
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.07.443200
Epub:
Not Epub
Abstract:
BACKGROUND: Spinocerebellar ataxia type 2 (SCA2) is a neurodegenerative disease caused by expansion of a CAG repeat in Ataxin-2...
Link:
https://www.biorxiv.org/content/10.1101/2021.05.07.443200v1
Citation Extract:
Li PP, Moulick R, Feng H, Sun X, Arbez N, Jin J, Marque LO, Hedglen E, Chan HYE, Ross CA, Pulst SM, Margolis RL, Woodson S, Rudnicki DD. RNA toxicity and perturbation of rRNA processing in spinocerebellar ataxia type 2. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.07.443200 .

Maternal factors regulating symmetry breaking and dorsal-ventral axis formation in the sea urchin embryo

Authors:
Molina MD, Lepage T
Citation:
Curr Top Dev Biol. 2020;140:283-316. doi: 10.1016/bs.ctdb.2019.10.007. Epub 2019 Nov 22
Epub:
Not Epub
Abstract:
Specification of the main axes of polarity of the embryo is an essential process during embryonic development. In many species...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0070215319300821
Organism or Cell Type:
sea urchin
Citation Extract:
Molina MD, Lepage T. Maternal factors regulating symmetry breaking and dorsal-ventral axis formation in the sea urchin embryo. Curr Top Dev Biol. 2020;140:283-316. doi: 10.1016/bs.ctdb.2019.10.007. Epub 2019 Nov 22.

Frizzled3 inhibits Vangl2-Prickle3 association to establish planar cell polarity in the vertebrate neural plate

Authors:
Chuykin I, Kim K, Sokol S
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.02.442356
Epub:
Not Epub
Abstract:
The orientation of epithelial cells in the plane of the tissue, known as planar cell polarity (PCP), is regulated by...
Link:
https://www.biorxiv.org/content/10.1101/2021.05.02.442356v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chuykin I, Kim K, Sokol S. Frizzled3 inhibits Vangl2-Prickle3 association to establish planar cell polarity in the vertebrate neural plate. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.02.442356.

A somatic piRNA pathway regulates epithelial-to-mesenchymal transition of chick neural crest cells

Authors:
Galton R, Fejes-Toth K, Bronner ME
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.30.442165
Epub:
Not Epub
Abstract:
In the metazoan germline, Piwi proteins play an essential regulatory role in maintenance of stemness and self-renewal by piRNA-...
Link:
https://www.biorxiv.org/content/10.1101/2021.04.30.442165v1.full
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Galton R, Fejes-Toth K, Bronner ME. A somatic piRNA pathway regulates epithelial-to-mesenchymal transition of chick neural crest cells. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.30.442165 .

Proapoptotic Bad Involved in Brain Development, When Severely Defected, Induces Dramatic Malformation in Zebrafish

Authors:
Hung J-C, Wu J-L, Hong J-R
Citation:
Int J Mol Sci. 2021;22:4832. doi:10.3390/ijms22094832
Epub:
Not Epub
Abstract:
The BH3-only molecule Bad regulates cell death via its differential protein phosphorylation, but very few studies address its...
Link:
https://www.mdpi.com/1422-0067/22/9/4832
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hung J-C, Wu J-L, Hong J-R. Proapoptotic Bad Involved in Brain Development, When Severely Defected, Induces Dramatic Malformation in Zebrafish. Int J Mol Sci. 2021;22:4832. doi:10.3390/ijms22094832.

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