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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Nectin-2 and N-cadherin interact through extracellular domains and induce apical accumulation of F-actin in apical constriction of Xenopus neural tube morphogenesis
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Citation:
Development. 2010 Apr;137(8):1315-25 Epub:
Not Epub Abstract:
Neural tube formation is one of the most dynamic morphogenetic processes of vertebrate development. However, the molecules... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Morita H, Nandadasa S, Yamamoto TS, Terasaka-Iioka C, Wylie C, Ueno N. Nectin-2 and N-cadherin interact through extracellular domains and induce apical accumulation of F-actin in apical constriction of Xenopus neural tube morphogenesis. Development. 2010 Apr;137(8):1315-25. |
Neucrin, a novel secreted antagonist of canonical Wnt signaling, plays roles in developing neural tissues in zebrafish
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Citation:
Mech Dev. 2012 Jan 12. [Epub ahead of print] Epub:
Not Epub Abstract:
Wnt signaling plays crucial roles in neural development. We previously identified Neucrin, a neural-specific secreted... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Miyake A, Nihno S, Murakoshi Y, Satsuka A, Nakayama Y, Itoh N. Neucrin, a novel secreted antagonist of canonical Wnt signaling, plays roles in developing neural tissues in zebrafish. Mech Dev. 2012 Jan 12. [Epub ahead of print]. |
Neuron and Sensory Epithelial Cell Fate Is Sequentially Determined by Notch Signaling in Zebrafish Lateral Line Development
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Citation:
J Neurosci. 2011;31(43):15522-30 doi:10.1523/JNEUROSCI.3948-11.2011 Epub:
Not Epub Abstract:
Sensory systems are specialized to recognize environmental changes. Sensory organs are complex structures composed of different... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Mizoguchi T, Togawa S, Kawakami K, Itoh M. Neuron and Sensory Epithelial Cell Fate Is Sequentially Determined by Notch Signaling in Zebrafish Lateral Line Development. J Neurosci. 2011;31(43):15522-30 doi:10.1523/JNEUROSCI.3948-11.2011 . |
Nuclear Wave1 Is Required for Reprogramming Transcription in Oocytes and for Normal Development
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Citation:
Science. 2013;341(6149):1002-5. doi:10.1126/science.1240376 Epub:
Not Epub Abstract:
Eggs and oocytes have a remarkable ability to induce transcription of sperm after normal fertilization and in somatic nuclei... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Miyamoto K, Teperek M, Yusa K, Allen GE, Bradshaw CR, Gurdon JB. Nuclear Wave1 Is Required for Reprogramming Transcription in Oocytes and for Normal Development. Science. 2013;341(6149):1002-5. doi:10.1126/science.1240376. |
Peptide-assisted delivery of steric-blocking antisense oligomers
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Citation:
Curr Opin Mol Ther. 2003 Apr;5(2):123-32 Epub:
Not Epub Abstract:
Cationic transport peptides conjugated to steric blocking antisense oligomers (oligos) increase oligo uptake in eukaryotic cell... Delivery Method:
not applicable Organism or Cell Type:
not applicable Citation Extract: Moulton HM, Moulton JD. Peptide-assisted delivery of steric-blocking antisense oligomers. Curr Opin Mol Ther. 2003 Apr;5(2):123-32. |
Personalised Genetic Intervention for Duchenne Muscular Dystrophy: Antisense Oligomers and Exon Skipping
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Citation:
Curr Mol Pharmacol. 2009 Jan;2(1):110-121 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) arises from protein-truncating mutations in the large dystrophin gene that preclude synthesis... Citation Extract: Mitrpant C, Fletcher S, Wilton SD. Personalised Genetic Intervention for Duchenne Muscular Dystrophy: Antisense Oligomers and Exon Skipping. Curr Mol Pharmacol. 2009 Jan;2(1):110-121. |
Perturbation of Notch/Suppressor of Hairless pathway disturbs migration of primordial germ cells in Xenopus embryo
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Citation:
Dev Growth Differ. 2010 Feb;52(2):235-44 Epub:
Not Epub Abstract:
Primordial germ cells (PGCs) in Xenopus embryo are specified in the endodermal cell mass and migrate dorsally toward the future... Organism or Cell Type:
Xenopus Citation Extract: Morichika K, Kataoka K, Terayama K, Tazaki A, Kinoshita T, Watanabe K, Mochii M. Perturbation of Notch/Suppressor of Hairless pathway disturbs migration of primordial germ cells in Xenopus embryo. Dev Growth Differ. 2010 Feb;52(2):235-44. |
Phosphorylation of Dpsyl2 (CRMP2) and Dpsyl3 (CRMP4) is required for positioning of caudal primary motor neurons in the zebrafish spinal cord
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Citation:
Devel Neurobio. 2013;[Epub ahead of print] doi:10.1002/dneu.22117 Epub:
Not Epub Abstract:
Dpysls (CRMPs) that were initially identified as mediator proteins of Semaphorin3a (Sem3a) signaling are involved in neuronal... Organism or Cell Type:
zebrafish Citation Extract: Morimura R, Nozawa K, Tanaka H, Ohshima T. Phosphorylation of Dpsyl2 (CRMP2) and Dpsyl3 (CRMP4) is required for positioning of caudal primary motor neurons in the zebrafish spinal cord. Devel Neurobio. 2013;[Epub ahead of print] doi:10.1002/dneu.22117. |
PlexinA4 is necessary as a downstream target of Islet2 to mediate Slit signaling for promotion of sensory axon branching
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Citation:
Development. 2004 Aug;131(15):3705-15. Epub:
Not Epub Abstract:
Slit is a secreted protein known to repulse the growth cones of commissural neurons. By contrast, Slit also promotes elongation... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Miyashita T, Yeo SY, Hirate Y, Segawa H, Wada H, Little MH, Yamada T, Takahashi N, Okamoto H. PlexinA4 is necessary as a downstream target of Islet2 to mediate Slit signaling for promotion of sensory axon branching. Development. 2004 Aug;131(15):3705-15.. |
Potent and Selective Inhibition of A-to-I RNA Editing with 2’-O-Methyl/Locked Nucleic Acid-containing Antisense Oligoribonucleotides
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Citation:
ACS Chem Biol. 2013;[Epub ahead of print] doi:10.1021/cb300692k Epub:
Not Epub Abstract:
ADARs (adenosine deaminases acting on RNA) are RNA editing enzymes that bind double helical RNAs and deaminate select... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: HeLa cells Citation Extract: Mizrahi RA, Schirle NT, Beal PA. Potent and Selective Inhibition of A-to-I RNA Editing with 2’-O-Methyl/Locked Nucleic Acid-containing Antisense Oligoribonucleotides. ACS Chem Biol. 2013;[Epub ahead of print] doi:10.1021/cb300692k. |