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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Function of Pax1 and Pax9 in the sclerotome of medaka fish

Authors:
Mise T, Iijima M, Inohaya K, Kudo A, Wada H
Citation:
Genesis. 2008 Apr 7;46(4):185-192 [Epub ahead of print]
Epub:
Not Epub
Abstract:
We examined the expression and functions of Pax1 and Pax9 in a teleost fish, the medaka Oryzias latipes. While Pax1 and Pax9...
Organism or Cell Type:
medaka embryos
Citation Extract:
Mise T, Iijima M, Inohaya K, Kudo A, Wada H. Function of Pax1 and Pax9 in the sclerotome of medaka fish. Genesis. 2008 Apr 7;46(4):185-192 [Epub ahead of print] .

Gene switching: analyzing a broad range of mutations using steric block antisense oligonucleotides

Authors:
Morcos PA
Citation:
Methods Enzymol 2000;313:174-89
Epub:
Not Epub
Abstract:
No abstract available.
Delivery Method:
Scrape Delivery
Organism or Cell Type:
Cell Culture: human HeLa pLuc 705 cell and HeLa pRLCMV
Citation Extract:
Morcos PA. Gene switching: analyzing a broad range of mutations using steric block antisense oligonucleotides. Methods Enzymol 2000;313:174-89.

Generation of FGF reporter transgenic zebrafish and their utility in chemical screens

Authors:
Molina GA, Watkins SC, Tsang M
Citation:
BMC Dev Biol. 2007 Jun 6;7:62
Epub:
Not Epub
Abstract:
BACKGROUND: Fibroblast Growth Factors (FGFs) represent a large family of secreted proteins that are required for proper...
Organism or Cell Type:
zebrafish
Citation Extract:
Molina GA, Watkins SC, Tsang M. Generation of FGF reporter transgenic zebrafish and their utility in chemical screens. BMC Dev Biol. 2007 Jun 6;7:62.

Genes required for functional glycosylation of dystroglycan are conserved in zebrafish

Authors:
Moore CJ, Goh HT, Hewitt JE
Citation:
Genomics. 2008 Sep;92(3):159-67. Epub 2008 Jul 15.
Epub:
Not Epub
Abstract:
Mutations in human genes encoding proteins involved in alpha-dystroglycan glycosylation result in dystroglycanopathies: severe...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Moore CJ, Goh HT, Hewitt JE. Genes required for functional glycosylation of dystroglycan are conserved in zebrafish. Genomics. 2008 Sep;92(3):159-67. Epub 2008 Jul 15..

Heartbeat regulates cardiogenesis by suppressing retinoic acid signaling via expression of miR-143

Authors:
Miyasaka KY, Kida YS, Banjo T, Ueki Y, Nagayama K, Matsumoto T, Sato M, Ogura T
Citation:
Mech Dev. 2011 Jan-Feb;128(1-2):18-28. Epub 2010 Sep 30
Epub:
Not Epub
Abstract:
Cardiogenesis proceeds with concomitant changes in hemodynamics to accommodate the circulatory demands of developing organs and...
Organism or Cell Type:
zebrafish
Citation Extract:
Miyasaka KY, Kida YS, Banjo T, Ueki Y, Nagayama K, Matsumoto T, Sato M, Ogura T. Heartbeat regulates cardiogenesis by suppressing retinoic acid signaling via expression of miR-143. Mech Dev. 2011 Jan-Feb;128(1-2):18-28. Epub 2010 Sep 30.

HIV Tat peptide enhances cellular delivery of antisense morpholino oligomers

Authors:
Moulton HM, Hase MC, Smith KM, Iversen PL
Citation:
Antisense Nucleic Acid Drug Dev. 2003 Feb;13(1):31-43
Epub:
Not Epub
Abstract:
Phosphorodiamidate morpholino oligomers (PMO) are uncharged antisense molecules that bind complementary sequences of RNA,...
Link:
http://online.liebertpub.com/doi/abs/10.1089/108729003764097322
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: various Hela
Citation Extract:
Moulton HM, Hase MC, Smith KM, Iversen PL. HIV Tat peptide enhances cellular delivery of antisense morpholino oligomers. Antisense Nucleic Acid Drug Dev. 2003 Feb;13(1):31-43.

Improved Antisense Oligonucleotide Design to Suppress Aberrant SMN2 Gene Transcript Processing: Towards a Treatment for Spinal Muscular Atrophy

Authors:
Mitrpant C, Porensky P, Zhou H, Price L, Muntoni F, Fletcher S, Wilton SD, Burghes AHM
Citation:
PLoS ONE. 2013;8(4):e62114. doi:10.1371/journal.pone.0062114
Epub:
Not Epub
Abstract:
Spinal muscular atrophy (SMA) is caused by loss of the Survival Motor Neuron 1 (SMN1) gene, resulting in reduced SMN protein....
Delivery Method:
ICV in vivo, DNA-MO complexes with lipofectin in vitro
Organism or Cell Type:
mouse SMA model
Citation Extract:
Mitrpant C, Porensky P, Zhou H, Price L, Muntoni F, Fletcher S, Wilton SD, Burghes AHM. Improved Antisense Oligonucleotide Design to Suppress Aberrant SMN2 Gene Transcript Processing: Towards a Treatment for Spinal Muscular Atrophy. PLoS ONE. 2013;8(4):e62114. doi:10.1371/journal.pone.0062114.

In Vivo Delivery of Morpholino Oligos by Cell-Penetrating Peptides

Authors:
Moulton HM
Citation:
Curr Pharm Des. 2013;19(16):2963-9
Epub:
Not Epub
Abstract:
Morpholino oligos (Morpholinos) are widely used tools for knocking down gene expression and are currently in a clinical trial...
Link:
http://www.ingentaconnect.com/content/ben/cpd/2013/00000019/00000016/art00010
Delivery Method:
peptide-coupled
Citation Extract:
Moulton HM. In Vivo Delivery of Morpholino Oligos by Cell-Penetrating Peptides. Curr Pharm Des. 2013;19(16):2963-9.

Inhibition of HSV-1 ocular infection with morpholino oligomers targeting ICP0 and ICP27

Authors:
Moerdyk-Schauwecker M, Stein DA, Eide K, Blouch RE, Bildfell R, Iversen P, Jin L
Citation:
Antiviral Res. 2009 Nov;84(2):131-41. Epub 2009 Aug 7.
Epub:
Not Epub
Abstract:
Alternative therapies are needed for HSV-1 infections in patients refractory to treatment with Acyclovir (ACV) and its...
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: Rabbit skin (RS) cells, Vero cells
Citation Extract:
Moerdyk-Schauwecker M, Stein DA, Eide K, Blouch RE, Bildfell R, Iversen P, Jin L. Inhibition of HSV-1 ocular infection with morpholino oligomers targeting ICP0 and ICP27. Antiviral Res. 2009 Nov;84(2):131-41. Epub 2009 Aug 7..

Inhibition of Intracellular Growth of Salmonella enterica serovar typhimurium in Tissue Culture by Antisense Peptide-Phosphorodiamidate Morpholino Oligomer

Authors:
Mitev GM, Mellbye BL, Iversen PL, Geller BL
Citation:
Antimicrob Agents Chemother. 2009 Jul 6. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Two types of phosphorodiamidate morpholino oligomers (PMOs) were tested for inhibition of growth of Salmonella enterica serovar...
Delivery Method:
peptide-coupled
Organism or Cell Type:
Salmonella enterica serovar typhimurium & infected macrophages
Citation Extract:
Mitev GM, Mellbye BL, Iversen PL, Geller BL. Inhibition of Intracellular Growth of Salmonella enterica serovar typhimurium in Tissue Culture by Antisense Peptide-Phosphorodiamidate Morpholino Oligomer. Antimicrob Agents Chemother. 2009 Jul 6. [Epub ahead of print].

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