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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Activin redux: specification of mesodermal pattern in Xenopus by graded concentrations of endogenous activin B

Authors:
Piepenburg O, Grimmer D, Williams PH, Smith JC
Citation:
Development. 2004 Oct;131(20):4977-86.
Epub:
Not Epub
Abstract:
Mesoderm formation in the amphibian embryo occurs through an inductive interaction in which cells of the vegetal hemisphere of...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Piepenburg O, Grimmer D, Williams PH, Smith JC. Activin redux: specification of mesodermal pattern in Xenopus by graded concentrations of endogenous activin B. Development. 2004 Oct;131(20):4977-86..

Activity-dependent competition regulates motor neuron axon pathfinding via PlexinA3

Authors:
Plazas PV, Nicol X, Spitzer NC
Citation:
PNAS. 2013;[Epub ahead of print] doi:10.1073/pnas.1213048110
Epub:
Not Epub
Abstract:
The role of electrical activity in axon guidance has been extensively studied in vitro. To better understand its role in the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Plazas PV, Nicol X, Spitzer NC. Activity-dependent competition regulates motor neuron axon pathfinding via PlexinA3. PNAS. 2013;[Epub ahead of print] doi:10.1073/pnas.1213048110 .

Amer2 is a novel negative regulator of Wnt/beta-catenin signaling involved in neuroectodermal patterning

Authors:
Pfister AS, Tanneberger K, Schambony A, Behrens J
Citation:
J Biol Chem. 2012 Jan 13;287(3):1734-41. doi: 10.1074/jbc.M111.308650. Epub 2011 Nov 28.
Epub:
Not Epub
Abstract:
Wnt/β-catenin signaling is negatively controlled by the tumor suppressor APC (adenomatous polyposis coli), which induces...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Pfister AS, Tanneberger K, Schambony A, Behrens J. Amer2 is a novel negative regulator of Wnt/beta-catenin signaling involved in neuroectodermal patterning. J Biol Chem. 2012 Jan 13;287(3):1734-41. doi: 10.1074/jbc.M111.308650. Epub 2011 Nov 28..

Amer2 Protein Interacts with EB1 Protein and Adenomatous Polyposis Coli (APC) and Controls Microtubule Stability and Cell Migration

Authors:
Pfister AS, Hadjihannas MV, Roehrig W, Schambony A, Behrens J
Citation:
J Biol Chem. 2012 Oct 12;287(42):35333-40. doi: 10.1074/jbc.M112.385393. Epub 2012 Aug 16.
Epub:
Not Epub
Abstract:
EB1 is key factor in the organization of the microtubule cytoskeleton by binding to the plus-ends of microtubules and serving...
Link:
http://www.jbc.org/content/287/42/35333.long
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Pfister AS, Hadjihannas MV, Roehrig W, Schambony A, Behrens J. Amer2 Protein Interacts with EB1 Protein and Adenomatous Polyposis Coli (APC) and Controls Microtubule Stability and Cell Migration. J Biol Chem. 2012 Oct 12;287(42):35333-40. doi: 10.1074/jbc.M112.385393. Epub 2012 Aug 16..

An LRP1-Dependent Endocytic Mechanism Governs the Signaling Output of the BMP System in Endothelial Cells and in Angiogenesis

Authors:
Pi X, Schmitt CE, Xie L, Portbury AL, Wu Y, Lockyer P, Dyer LA, Moser M, Bu G, Flynn EJ, Jin S-W, Patterson C
Citation:
Circ Res. 2012 Aug 17;111(5):564-74. doi: 10.1161/CIRCRESAHA.112.274597. Epub 2012 Jul 9.
Epub:
Not Epub
Abstract:
Rationale: Among the extracellular modulators of Bmp (bone morphogenetic protein) signaling, Bmper (Bmp endothelial cell...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pi X, Schmitt CE, Xie L, Portbury AL, Wu Y, Lockyer P, Dyer LA, Moser M, Bu G, Flynn EJ, Jin S-W, Patterson C. An LRP1-Dependent Endocytic Mechanism Governs the Signaling Output of the BMP System in Endothelial Cells and in Angiogenesis. Circ Res. 2012 Aug 17;111(5):564-74. doi: 10.1161/CIRCRESAHA.112.274597. Epub 2012 Jul 9..

Analyzing retinal axon guidance in zebrafish

Authors:
Poulain FE, Gaynes JA, Hörndli CS, Law MY, Chien CB
Citation:
Methods Cell Biol. 2010;100:2-26
Epub:
Not Epub
Abstract:
How neuronal connections are established during development is one of the most fascinating questions in the field of...
Organism or Cell Type:
zebrafish
Citation Extract:
Poulain FE, Gaynes JA, Hörndli CS, Law MY, Chien CB. Analyzing retinal axon guidance in zebrafish. Methods Cell Biol. 2010;100:2-26.

Bioinformatic and Functional Optimization of Antisense Phosphorodiamidate Morpholino Oligomers (PMOs) for Therapeutic Modulation of RNA Splicing in Muscle

Authors:
Popplewell LJ, Graham IR, Malerba A, Dickson G
Citation:
Methods Mol Biol. 2011;709:153-78
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is caused by mutations that disrupt the reading frame of the human DMD gene. Selective...
Citation Extract:
Popplewell LJ, Graham IR, Malerba A, Dickson G. Bioinformatic and Functional Optimization of Antisense Phosphorodiamidate Morpholino Oligomers (PMOs) for Therapeutic Modulation of RNA Splicing in Muscle. Methods Mol Biol. 2011;709:153-78.

Combinatorial function of ETS transcription factors in the developing vasculature

Authors:
Pham VN, Lawson ND, Mugford JW, Dye L, Castranova D, Lo B, Weinstein BM
Citation:
Dev Biol. 2007 Mar 15;303(2):772-83. Epub 2006 Oct 25.
Epub:
Not Epub
Abstract:
Members of the ETS family of transcription factors are among the first genes expressed in the developing vasculature, but loss-...
Organism or Cell Type:
zebrafish
Citation Extract:
Pham VN, Lawson ND, Mugford JW, Dye L, Castranova D, Lo B, Weinstein BM. Combinatorial function of ETS transcription factors in the developing vasculature. Dev Biol. 2007 Mar 15;303(2):772-83. Epub 2006 Oct 25..

Common genetic control of haemangioblast and cardiac development in zebrafish

Authors:
Peterkin T, Gibson A, Patient R
Citation:
Development. 2009 May;136(9):1465-74. Epub 2009 Mar 18
Epub:
Not Epub
Abstract:
Over the past few years it has become clear that over half of the mammalian heart derives from outside the heart field as...
Organism or Cell Type:
zebrafish
Citation Extract:
Peterkin T, Gibson A, Patient R. Common genetic control of haemangioblast and cardiac development in zebrafish. Development. 2009 May;136(9):1465-74. Epub 2009 Mar 18.

Comparative analysis of antisense oligonucleotide sequences targeting exon 53 of the human DMD gene: Implications for future clinical trials

Authors:
Popplewell LJ, Adkin C, Arechavala-Gomeza V, Aartsma-Rus A, de Winter CL, Wilton SD, Morgan JE, Muntoni F, Graham IR, Dickson G
Citation:
Neuromuscul Disord. 2010 Jan 13. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is caused by the lack of functional dystrophin protein, most commonly as a result of a range...
Link:
https://www.nmd-journal.com/article/S0960-8966(09)00666-X/abstract
Delivery Method:
Electroporation (Amaxa)
Organism or Cell Type:
mouse expressing human dystrophin, cultured DMD cells
Citation Extract:
Popplewell LJ, Adkin C, Arechavala-Gomeza V, Aartsma-Rus A, de Winter CL, Wilton SD, Morgan JE, Muntoni F, Graham IR, Dickson G. Comparative analysis of antisense oligonucleotide sequences targeting exon 53 of the human DMD gene: Implications for future clinical trials. Neuromuscul Disord. 2010 Jan 13. [Epub ahead of print].

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