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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
A gene regulatory network controlling the embryonic specification of endoderm
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Citation:
Nature. 2011 May 29. [Epub ahead of print] Epub:
Not Epub Abstract:
Specification of endoderm is the prerequisite for gut formation in the embryogenesis of bilaterian organisms. Modern lineage... Delivery Method:
Microinjection Organism or Cell Type:
Sea urchin, Strongylocentrotus purpuratus Citation Extract: Peter IS, Davidson EH. A gene regulatory network controlling the embryonic specification of endoderm. Nature. 2011 May 29. [Epub ahead of print]. |
A novel positive transcriptional feedback loop in midbrain-hindbrain boundary development is revealed through analysis of the zebrafish pax2.1 promoter in transgenic lines
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Citation:
Development. 2002 Jul 1;129(13):3227-3239 Epub:
Not Epub Abstract:
The pax2.1 gene encodes a paired-box transcription factor that is one of the earliest genes to be specifically activated in... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Picker A, Scholpp S, Bohli H, Takeda H, Brand M.. A novel positive transcriptional feedback loop in midbrain-hindbrain boundary development is revealed through analysis of the zebrafish pax2.1 promoter in transgenic lines. Development. 2002 Jul 1;129(13):3227-3239. |
A novel role for Glucocorticoid-Induced TNF Receptor Ligand (Gitrl) in early embryonic zebrafish development
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Citation:
Int J Dev Biol. 2009 Jul 1. [Epub ahead of print] Epub:
Not Epub Abstract:
Tumour necrosis factor ligand and receptor superfamily (TNFSF and TNFRSF) members have diverse and well-studied functions in... Organism or Cell Type:
zebrafish Citation Extract: Poulton LD, Nolan KF, Anastasaki C, Waldmann H, Patton EE. A novel role for Glucocorticoid-Induced TNF Receptor Ligand (Gitrl) in early embryonic zebrafish development. Int J Dev Biol. 2009 Jul 1. [Epub ahead of print]. |
A Polarised Population of Dynamic Microtubules Mediates Homeostatic Length Control in Animal Cells
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Citation:
PLoS Biol 2010;8(11): e1000542. doi:10.1371/journal.pbio.1000542 Epub:
Not Epub Abstract:
Because physical form and function are intimately linked, mechanisms that maintain cell shape and size within strict limits are... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Picone R, Ren X, Ivanovitch KD, Clarke JDW, McKendry RA, Baum B. A Polarised Population of Dynamic Microtubules Mediates Homeostatic Length Control in Animal Cells. PLoS Biol 2010;8(11): e1000542. doi:10.1371/journal.pbio.1000542. |
A revised model of Xenopus dorsal midline development: differential and separable requirements for Notch and Shh signaling
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Citation:
Dev Biol. 2011 Apr 15;352(2):254-66. Epub 2011 Jan 27 Epub:
Not Epub Abstract:
The development of the vertebrate dorsal midline (floor plate, notochord, and hypochord) has been an area of classical research... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Peyrot SM, Wallingford JB, Harland RM. A revised model of Xenopus dorsal midline development: differential and separable requirements for Notch and Shh signaling. Dev Biol. 2011 Apr 15;352(2):254-66. Epub 2011 Jan 27. |
A single administration of morpholino antisense oligomer rescues spinal muscular atrophy in the mouse
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Citation:
Hum Mol Genet. 2012 Apr 1;21(7):1625-38. Epub 2011 Dec 20. doi:10.1093/hmg/ddr600 Epub:
Not Epub Abstract:
Spinal Muscular Atrophy (SMA) is an autosomal recessive disorder characterized by α-motor neuron loss in the spinal cord... Delivery Method:
injection, intracerebroventricular Organism or Cell Type:
mice, SMA model Citation Extract: Porensky PM, Mitrpant C, McGovern VL, Bevan AK, Foust KD, Kaspar BK, Wilton SD, Burghes AHM. A single administration of morpholino antisense oligomer rescues spinal muscular atrophy in the mouse. Hum Mol Genet. 2012 Apr 1;21(7):1625-38. Epub 2011 Dec 20. doi:10.1093/hmg/ddr600. |
A study of mesoderm patterning through the analysis of the regulation of Xmyf-5 expression.
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Citation:
Development. 2002 Jun;129(12):2917-27 Epub:
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Xenopus laevis has been a particularly useful model organism for identifying factors involved in the induction and patterning... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Polli M, Amaya E. A study of mesoderm patterning through the analysis of the regulation of Xmyf-5 expression.. Development. 2002 Jun;129(12):2917-27. |
A tissue restricted role for the Xenopus Jun N-terminal kinase kinase kinase MLK2 in cement gland and pronephric tubule differentiation
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Citation:
Dev Biol. 2003 Feb 15;254(2):200-14 Epub:
Not Epub Abstract:
The MLK family of mitogen activated protein kinase kinase kinases (MAPKKK) has been shown to activate Jun N-terminal kinase/... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Poitras L, Bisson N, Islam N, Moss T. A tissue restricted role for the Xenopus Jun N-terminal kinase kinase kinase MLK2 in cement gland and pronephric tubule differentiation. Dev Biol. 2003 Feb 15;254(2):200-14. |
A two-step model for colon adenoma initiation and progression caused by APC loss
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Citation:
Cell. 2009 May 15;137(4):623-34 Epub:
Not Epub Abstract:
Aberrant Wnt/beta-catenin signaling following loss of the tumor suppressor adenomatous polyposis coli (APC) is thought to... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Phelps RA, Chidester S, Dehghanizadeh S, Phelps J, Sandoval IT, Rai K, Broadbent T, Sarkar S, Burt RW, Jones DA. A two-step model for colon adenoma initiation and progression caused by APC loss. Cell. 2009 May 15;137(4):623-34. |
Activation of Endogenous FAK via Expression of Its Amino Terminal Domain in Xenopus Embryos
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Citation:
PLoS One. 2012;7(8):e42577. Epub 2012 Aug 6 Epub:
Not Epub Abstract:
Background The Focal Adhesion Kinase is a well studied tyrosine kinase involved in a wide number of cellular processes... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Petridou NI, Stylianou P, Christodoulou N, Rhoads D, Guan JL, Skourides PA. Activation of Endogenous FAK via Expression of Its Amino Terminal Domain in Xenopus Embryos. PLoS One. 2012;7(8):e42577. Epub 2012 Aug 6. |