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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Dnmt2 functions in the cytoplasm to promote liver, brain, and retina development in zebrafish

Authors:
Rai K, Chidester S, Zavala CV, Manos EJ, James SR, Karpf AR, Jones DA, Cairns BR
Citation:
Genes Dev. 2007 Feb 1;21(3):261-6
Epub:
Not Epub
Abstract:
The roles of DNA methyltransferase-2 (DNMT2) enzymes are controversial; whether DNMT2 functions primarily as a nuclear DNA...
Organism or Cell Type:
zebrafish
Citation Extract:
Rai K, Chidester S, Zavala CV, Manos EJ, James SR, Karpf AR, Jones DA, Cairns BR. Dnmt2 functions in the cytoplasm to promote liver, brain, and retina development in zebrafish. Genes Dev. 2007 Feb 1;21(3):261-6.

Dnmt3 and G9a cooperate for tissue-specific development in zebrafish

Authors:
Rai K, Jafri IF, Chidester S, James SR, Karpf AR, Cairns BR, Jones DA
Citation:
J Biol Chem. 2009 Nov 29. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Although DNA methylation is critical for proper embryonic and tissue-specific development, how different DNA methyltransferases...
Organism or Cell Type:
zebrafish
Citation Extract:
Rai K, Jafri IF, Chidester S, James SR, Karpf AR, Cairns BR, Jones DA. Dnmt3 and G9a cooperate for tissue-specific development in zebrafish. J Biol Chem. 2009 Nov 29. [Epub ahead of print].

Endocrine-committed progenitor cells retain their differentiation potential in the absence of neurogenin-3 expression

Authors:
Prasadan K, Tulachan S, Guo P, Shiota C, Shah S, Gittes G
Citation:
Biochem Biophys Res Commun. 2010 Jun 11;396(4):1036-41. doi: 10.1016/j.bbrc.2010.05.058. Epub 2010 May 13
Epub:
Not Epub
Abstract:
Neurogenin-3 (ngn-3) expression is critical for endocrine development in the developing pancreas. We found that when ngn-3 was...
Delivery Method:
oligo bathing
Organism or Cell Type:
Mouse pancreas explant
Citation Extract:
Prasadan K, Tulachan S, Guo P, Shiota C, Shah S, Gittes G. Endocrine-committed progenitor cells retain their differentiation potential in the absence of neurogenin-3 expression. Biochem Biophys Res Commun. 2010 Jun 11;396(4):1036-41. doi: 10.1016/j.bbrc.2010.05.058. Epub 2010 May 13.

Endoderm-derived Sonic hedgehog and mesoderm Hand2 expression are required for enteric nervous system development in zebrafish

Authors:
Reichenbach B, Delalande JM, Kolmogorova E, Prier A, Nguyen T, Smith CM, Holzschuh J, Shepherd IT
Citation:
Dev Biol. 2008 Jun 1;318(1):52-64. Epub 2008 Mar 20
Epub:
Not Epub
Abstract:
The zebrafish enteric nervous system (ENS), like those of all other vertebrate species, is principally derived from the vagal...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Reichenbach B, Delalande JM, Kolmogorova E, Prier A, Nguyen T, Smith CM, Holzschuh J, Shepherd IT. Endoderm-derived Sonic hedgehog and mesoderm Hand2 expression are required for enteric nervous system development in zebrafish. Dev Biol. 2008 Jun 1;318(1):52-64. Epub 2008 Mar 20.

Exploring Zebrafish Genomic, Functional and Phenotypic Data Using ZFIN

Authors:
Ramachandran S, Ruef B, Pich C, Sprague J
Citation:
Curr Protoc Bioinformatics. 2010 Sep;Chapter 1:Unit1.18
Epub:
Not Epub
Abstract:
The zebrafish model organism database (ZFIN) provides a Web resource of zebrafish genomic, genetic, developmental, and...
Organism or Cell Type:
zebrafish
Citation Extract:
Ramachandran S, Ruef B, Pich C, Sprague J. Exploring Zebrafish Genomic, Functional and Phenotypic Data Using ZFIN. Curr Protoc Bioinformatics. 2010 Sep;Chapter 1:Unit1.18.

Functional analysis of BBS3 A89V that results in non-syndromic retinal degeneration

Authors:
Pretorius PR, Aldahmesh MA, Alkuraya FS, Sheffield VC, Slusarski DC
Citation:
Hum Mol Genet. 2011 Jan 31. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Bardet-Biedl Syndrome (BBS) is a syndromic form of retinal degeneration. Recently, homozygosity mapping with a consanguineous...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pretorius PR, Aldahmesh MA, Alkuraya FS, Sheffield VC, Slusarski DC. Functional analysis of BBS3 A89V that results in non-syndromic retinal degeneration. Hum Mol Genet. 2011 Jan 31. [Epub ahead of print].

Germline gain-of-function mutations in RAF1 cause Noonan syndrome

Authors:
Razzaque MA, Nishizawa T, Komoike Y, Yagi H, Furutani M, Amo R, Kamisago M, Momma K, Katayama H, Nakagawa M, Fujiwara Y, Matsushima M, Mizuno K, Tokuyama M, Hirota H, Muneuchi J, Higashinakagawa T, Matsuoka R
Citation:
Nat Genet. 2007 Aug;39(8):1013-7. Epub 2007 Jul 1.
Epub:
Not Epub
Abstract:
Noonan syndrome is characterized by short stature, facial dysmorphia and a wide spectrum of congenital heart defects. Mutations...
Organism or Cell Type:
zebrafish
Citation Extract:
Razzaque MA, Nishizawa T, Komoike Y, Yagi H, Furutani M, Amo R, Kamisago M, Momma K, Katayama H, Nakagawa M, Fujiwara Y, Matsushima M, Mizuno K, Tokuyama M, Hirota H, Muneuchi J, Higashinakagawa T, Matsuoka R. Germline gain-of-function mutations in RAF1 cause Noonan syndrome. Nat Genet. 2007 Aug;39(8):1013-7. Epub 2007 Jul 1..

Glucagon is required for early insulin-positive differentiation in the developing mouse pancreas

Authors:
Prasadan K, Daume E, Preuett B, Spilde T, Bhatia A, Kobayashi H, Hembree M, Manna P, Gittes GK
Citation:
Diabetes. 2002 Nov;51(11):3229-36
Epub:
Not Epub
Abstract:
The embryonic pancreas is thought to develop from pluripotent endodermal cells that give rise to endocrine and exocrine cells....
Delivery Method:
oligo bathing
Organism or Cell Type:
Mouse embryonic tissue
Citation Extract:
Prasadan K, Daume E, Preuett B, Spilde T, Bhatia A, Kobayashi H, Hembree M, Manna P, Gittes GK. Glucagon is required for early insulin-positive differentiation in the developing mouse pancreas. Diabetes. 2002 Nov;51(11):3229-36.

Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins

Authors:
Rajagopal A, Rao AU, Amigo J, Tian M, Upadhyay SK, Hall C, Uhm S, Mathew MK, Fleming MD, Paw BH, Krause M, Hamza I
Citation:
Nature. 2008 Jun 19;453(7198):1127-31. Epub 2008 Apr 16
Epub:
Not Epub
Abstract:
Haems are metalloporphyrins that serve as prosthetic groups for various biological processes including respiration, gas sensing...
Organism or Cell Type:
zebrafish
Citation Extract:
Rajagopal A, Rao AU, Amigo J, Tian M, Upadhyay SK, Hall C, Uhm S, Mathew MK, Fleming MD, Paw BH, Krause M, Hamza I. Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins. Nature. 2008 Jun 19;453(7198):1127-31. Epub 2008 Apr 16.

Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development

Authors:
Qi HH, Sarkissian M, Hu GQ, Wang Z, Bhattacharjee A, Gordon DB, Gonzales M, Lan F, Ongusaha PP, Huarte M, Yaghi NK, Lim H, Garcia BA, Brizuela L, Zhao K, Roberts TM, Shi Y
Citation:
Nature. 2010 Jul 22;466(7305):503-7. Epub 2010 Jul 11
Epub:
Not Epub
Abstract:
X-linked mental retardation (XLMR) is a complex human disease that causes intellectual disability. Causal mutations have been...
Organism or Cell Type:
zebrafish
Citation Extract:
Qi HH, Sarkissian M, Hu GQ, Wang Z, Bhattacharjee A, Gordon DB, Gonzales M, Lan F, Ongusaha PP, Huarte M, Yaghi NK, Lim H, Garcia BA, Brizuela L, Zhao K, Roberts TM, Shi Y. Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development. Nature. 2010 Jul 22;466(7305):503-7. Epub 2010 Jul 11.

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