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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Ascl1a regulates Müller glia dedifferentiation and retinal regeneration through a Lin-28-dependent, let-7 microRNA signalling pathway

Authors:
Ramachandran R, Fausett BV, Goldman D
Citation:
Nat Cell Biol. 2010 Oct 10. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Unlike mammals, teleost fish mount a robust regenerative response to retinal injury that culminates in restoration of visual...
Organism or Cell Type:
zebrafish
Citation Extract:
Ramachandran R, Fausett BV, Goldman D. Ascl1a regulates Müller glia dedifferentiation and retinal regeneration through a Lin-28-dependent, let-7 microRNA signalling pathway. Nat Cell Biol. 2010 Oct 10. [Epub ahead of print].

Ascl1a/Dkk/{beta}-catenin signaling pathway is necessary and glycogen synthase kinase-3{beta} inhibition is sufficient for zebrafish retina regeneration

Authors:
Ramachandran R, Zhao XF, Goldman D
Citation:
Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15858-63. Epub 2011 Sep 12.
Epub:
Not Epub
Abstract:
Key to successful retina regeneration in zebrafish are Müller glia (MG) that respond to retinal injury by dedifferentiating...
Delivery Method:
Electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Ramachandran R, Zhao XF, Goldman D. Ascl1a/Dkk/{beta}-catenin signaling pathway is necessary and glycogen synthase kinase-3{beta} inhibition is sufficient for zebrafish retina regeneration. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15858-63. Epub 2011 Sep 12..

Autotaxin Signaling via Lysophosphatidic Acid Receptors Contributes to Vascular Endothelial Growth Factor-Induced Endothelial Cell Migration

Authors:
Ptaszynska MM, Pendrak ML, Stracke ML, Roberts DD
Citation:
Mol Cancer Res. 2010 Mar;8(3):309-21. Epub 2010 Mar 2
Epub:
Not Epub
Abstract:
Important roles for vascular endothelial growth factor (VEGF) and autotaxin (ATX) have been established for embryonic...
Delivery Method:
Endo-Porter
Organism or Cell Type:
Cell Culture: human umbilical vein endothelial cells (HUVECs)
Citation Extract:
Ptaszynska MM, Pendrak ML, Stracke ML, Roberts DD. Autotaxin Signaling via Lysophosphatidic Acid Receptors Contributes to Vascular Endothelial Growth Factor-Induced Endothelial Cell Migration. Mol Cancer Res. 2010 Mar;8(3):309-21. Epub 2010 Mar 2.

Bacterial Resistance to Antisense Peptide-Phosphorodiamidate Morpholino Oligomers

Authors:
Puckett SE, Reese KA, Mitev GM, Mullen V, Johnson RC, Pomraning KR, Mellbye BL, Tilley LD, Iversen PL, Freitag M, Geller BL
Citation:
Antimicrob Agents Chemother. 2012 Sep 17. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Peptide phosphorodiamidate morpholino oligomers (PPMO) are synthetic DNA mimics that bind complementary RNA and inhibit...
Delivery Method:
peptide-coupled
Organism or Cell Type:
Escherichia coli
Citation Extract:
Puckett SE, Reese KA, Mitev GM, Mullen V, Johnson RC, Pomraning KR, Mellbye BL, Tilley LD, Iversen PL, Freitag M, Geller BL. Bacterial Resistance to Antisense Peptide-Phosphorodiamidate Morpholino Oligomers. Antimicrob Agents Chemother. 2012 Sep 17. [Epub ahead of print].

Bcl-wav and the mitochondrial calcium uniporter drive gastrula morphogenesis in zebrafish

Authors:
Prudent J, Popgeorgiev N, Bonneau B, Thibaut J, Gadet R, Lopez J, Gonzalo P, Rimokh R, Manon S, Houart C, Herbomel P, Aouacheria A, Gillet G
Citation:
Nat Commun. 2013 Aug 14;4:2330. doi: 10.1038/ncomms3330.
Epub:
Not Epub
Abstract:
Bcl-2 proteins are acknowledged as key regulators of programmed cell death. However, increasing data suggest additional roles,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Prudent J, Popgeorgiev N, Bonneau B, Thibaut J, Gadet R, Lopez J, Gonzalo P, Rimokh R, Manon S, Houart C, Herbomel P, Aouacheria A, Gillet G. Bcl-wav and the mitochondrial calcium uniporter drive gastrula morphogenesis in zebrafish. Nat Commun. 2013 Aug 14;4:2330. doi: 10.1038/ncomms3330..

BMP signaling orchestrates photoreceptor specification in the zebrafish pineal gland in collaboration with Notch

Authors:
Quillien A, Blanco-Sanchez B, Halluin C, Moore JC, Lawson ND, Blader P, Cau E
Citation:
Development. 2011 June 1;138:2293-302. doi: 10.1242/dev.060988
Epub:
Not Epub
Abstract:
A variety of signaling pathways have been shown to regulate specification of neuronal subtype identity. However, the mechanisms...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Quillien A, Blanco-Sanchez B, Halluin C, Moore JC, Lawson ND, Blader P, Cau E. BMP signaling orchestrates photoreceptor specification in the zebrafish pineal gland in collaboration with Notch. Development. 2011 June 1;138:2293-302. doi: 10.1242/dev.060988.

Calcium influx through L-type CaV1.2 Ca2+ channels regulates mandibular development

Authors:
Ramachandran KV, Hennessey JA, Barnett AS, Yin X, Stadt HA, Foster E, Shah RA, Yazawa M, Dolmetsch RE, Kirby ML, Pitt GS
Citation:
J Clin Invest. 2013;[Epub ahead of print] doi:10.1172/JCI66903
Epub:
Not Epub
Abstract:
The identification of a gain-of-function mutation in CACNA1C as the cause of Timothy Syndrome (TS), a rare disorder...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ramachandran KV, Hennessey JA, Barnett AS, Yin X, Stadt HA, Foster E, Shah RA, Yazawa M, Dolmetsch RE, Kirby ML, Pitt GS. Calcium influx through L-type CaV1.2 Ca2+ channels regulates mandibular development. J Clin Invest. 2013;[Epub ahead of print] doi:10.1172/JCI66903 .

Cell-autonomous integrin control of Wnt and Notch signalling during somitogenesis

Authors:
Rallis C, Pinchin SM, Ish-Horowicz D
Citation:
Development. 2010 Nov;137(21):3591-601. Epub 2010 Sep 28
Epub:
Not Epub
Abstract:
Integrins act at signalling crossroads, and their interactions with other signal transduction pathways are key to the...
Delivery Method:
Electroporation
Organism or Cell Type:
chick embryo
Citation Extract:
Rallis C, Pinchin SM, Ish-Horowicz D. Cell-autonomous integrin control of Wnt and Notch signalling during somitogenesis. Development. 2010 Nov;137(21):3591-601. Epub 2010 Sep 28.

Cellular Requirements for Building a Retinal Neuropil

Authors:
Randlett O, MacDonald RB, Yoshimatsu T, Almeida AD, Suzuki SC, Wong RO, Harris WA
Citation:
Cell Reports. 2013;[Epub ahead of print] doi:10.1016/j.celrep.2013.01.020
Epub:
Not Epub
Abstract:
How synaptic neuropil is formed within the CNS is poorly understood. The retinal inner plexiform layer (IPL) is positioned...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Randlett O, MacDonald RB, Yoshimatsu T, Almeida AD, Suzuki SC, Wong RO, Harris WA. Cellular Requirements for Building a Retinal Neuropil. Cell Reports. 2013;[Epub ahead of print] doi:10.1016/j.celrep.2013.01.020.

Characterization of a novel KRAS mutation identified in Noonan syndrome

Authors:
Razzaque MA, Komoike Y, Nishizawa T, Inai K, Furutani M, Higashinakagawa T, Matsuoka R
Citation:
Am J Med Genet A. 2012 Feb 2. doi: 10.1002/ajmg.a.34419. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Noonan syndrome (NS) is the most common non-chromosomal syndrome seen in children and is characterized by short stature,...
Organism or Cell Type:
zebrafish
Citation Extract:
Razzaque MA, Komoike Y, Nishizawa T, Inai K, Furutani M, Higashinakagawa T, Matsuoka R. Characterization of a novel KRAS mutation identified in Noonan syndrome. Am J Med Genet A. 2012 Feb 2. doi: 10.1002/ajmg.a.34419. [Epub ahead of print].

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