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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans

Authors:
Van Hoecke A, Schoonaert L, Lemmens R, Timmers M, Staats KA, Laird AS, Peeters E, Philips T, Goris A, Dubois B, Andersen PM, Al-Chalabi A, Thijs V, Turnley AM, van Vught PW, Veldink JH, Hardiman O, Van Den Bosch L, Gonzalez-Perez P, Van Damme P, Brown RH Jr, van den Berg LH, Robberecht W.
Citation:
Nat Med. 2012 Aug 26. doi: 10.1038/nm.2901. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting motor neurons. Disease onset and progression...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Van Hoecke A, Schoonaert L, Lemmens R, Timmers M, Staats KA, Laird AS, Peeters E, Philips T, Goris A, Dubois B, Andersen PM, Al-Chalabi A, Thijs V, Turnley AM, van Vught PW, Veldink JH, Hardiman O, Van Den Bosch L, Gonzalez-Perez P, Van Damme P, Brown RH Jr, van den Berg LH, Robberecht W.. EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans. Nat Med. 2012 Aug 26. doi: 10.1038/nm.2901. [Epub ahead of print].

Etsrp/Etv2 Is Directly Regulated by Foxc1a/b in the Zebrafish Angioblast

Authors:
Veldman MB, Lin S
Citation:
Circ Res. 2011 Dec 1. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Rationale:Endothelial cells are developmentally derived from angioblasts specified in the mesodermal germ cell layer. The...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Veldman MB, Lin S. Etsrp/Etv2 Is Directly Regulated by Foxc1a/b in the Zebrafish Angioblast. Circ Res. 2011 Dec 1. [Epub ahead of print].

Eye defects in receptor protein-tyrosine phosphatase [alpha] knock-down zebrafish

Authors:
Van Der Sar AM, Zivkovic D, Den Hertog J
Citation:
Dev Dyn. 2002 Feb;223(2):292-297
Epub:
Not Epub
Abstract:
Receptor protein-tyrosine phosphatase alpha (RPTP alpha) is highly expressed in the developing retina of different species, but...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Van Der Sar AM, Zivkovic D, Den Hertog J. Eye defects in receptor protein-tyrosine phosphatase [alpha] knock-down zebrafish. Dev Dyn. 2002 Feb;223(2):292-297.

FGF is essential for both condensation and mesenchymal-epithelial transition stages of pronephric kidney tubule development

Authors:
Urban AE, Zhou X, Ungos JM, Raible DW, Altmann CR, Vize PD
Citation:
Dev Biol. 2006 Sep 1;297(1):103-17. Epub 2006 May 5.
Epub:
Not Epub
Abstract:
The pronephros is a transient embryonic kidney that is essential for the survival of aquatic larvae. It is also absolutely...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Urban AE, Zhou X, Ungos JM, Raible DW, Altmann CR, Vize PD. FGF is essential for both condensation and mesenchymal-epithelial transition stages of pronephric kidney tubule development. Dev Biol. 2006 Sep 1;297(1):103-17. Epub 2006 May 5..

Flow on the right side of the gastrocoel roof plate is dispensable for symmetry breakage in the frog Xenopus laevis

Authors:
Vick P, Schweickert A, Weber T, Eberhardt M, Mencl S, Shcherbakov D, Beyer T, Blum M
Citation:
Dev Biol. 2009 May 15. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Leftward flow of extracellular fluid breaks the bilateral symmetry of most vertebrate embryos, manifested by the ensuing...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Vick P, Schweickert A, Weber T, Eberhardt M, Mencl S, Shcherbakov D, Beyer T, Blum M. Flow on the right side of the gastrocoel roof plate is dispensable for symmetry breakage in the frog Xenopus laevis. Dev Biol. 2009 May 15. [Epub ahead of print].

Functional analysis of FGF3 during zebrafish inner ear development.

Authors:
Vendrell V, Gimnopoulos D, Becker T and Schimmang T
Citation:
Int. J. Dev. Biol. 2001 45 (S1): S105-S106
Epub:
Not Epub
Abstract:
FGF3 has been involved in the development of the inner ear in a number of species including mouse, chicken and Xenopus....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Vendrell V, Gimnopoulos D, Becker T and Schimmang T. Functional analysis of FGF3 during zebrafish inner ear development.. Int. J. Dev. Biol. 2001 45 (S1): S105-S106.

Gene expression analysis of zebrafish retinal ganglion cells during optic nerve regeneration identifies KLF6a and KLF7a as important regulators of axon regeneration

Authors:
Veldman MB, Bemben MA, Thompson RC, Goldman D
Citation:
Dev Biol. 2007 Dec 15;312(2):596-612. Epub 2007 Sep 22
Epub:
Not Epub
Abstract:
Unlike mammals, teleost fish are able to mount an efficient and robust regenerative response following optic nerve injury....
Delivery Method:
Gelfoam at lesion
Organism or Cell Type:
zebrafish
Citation Extract:
Veldman MB, Bemben MA, Thompson RC, Goldman D. Gene expression analysis of zebrafish retinal ganglion cells during optic nerve regeneration identifies KLF6a and KLF7a as important regulators of axon regeneration. Dev Biol. 2007 Dec 15;312(2):596-612. Epub 2007 Sep 22.

Gene-Specific Ebola Therapies Protect Nonhuman Primates from Lethal Diseases

Authors:
Vander-Linden CL
Citation:
Chem-Bio Defense Quarterly. 2006 3(2):8-9
Epub:
Not Epub
Abstract:
First paragraph: It was February 11, 2004, and the female scientist was working in a Bio-Safety Level 4 maximum containment...
Citation Extract:
Vander-Linden CL. Gene-Specific Ebola Therapies Protect Nonhuman Primates from Lethal Diseases. Chem-Bio Defense Quarterly. 2006 3(2):8-9.

Genome-Wide RNA Interference in Drosophila Cells Identifies G Protein-Coupled Receptor Kinase 2 as a Conserved Regulator of NF-kappaB Signaling

Authors:
Valanne S, Myllymäki H, Kallio J, Schmid MR, Kleino A, Murumägi A, Airaksinen L, Kotipelto T, Kaustio M, Ulvila J, Esfahani SS, Engström Y, Silvennoinen O, Hultmark D, Parikka M, Rämet M
Citation:
2010 Jun 1;184(11):6188-98. doi: 10.4049/jimmunol.1000261. Epub 2010 Apr 26.
Epub:
Not Epub
Abstract:
Because NF-kappaB signaling pathways are highly conserved in evolution, the fruit fly Drosophila melanogaster provides a good...
Organism or Cell Type:
zebrafish
Citation Extract:
Valanne S, Myllymäki H, Kallio J, Schmid MR, Kleino A, Murumägi A, Airaksinen L, Kotipelto T, Kaustio M, Ulvila J, Esfahani SS, Engström Y, Silvennoinen O, Hultmark D, Parikka M, Rämet M. Genome-Wide RNA Interference in Drosophila Cells Identifies G Protein-Coupled Receptor Kinase 2 as a Conserved Regulator of NF-kappaB Signaling. 2010 Jun 1;184(11):6188-98. doi: 10.4049/jimmunol.1000261. Epub 2010 Apr 26..

Gli function is essential for motor neuron induction in zebrafish

Authors:
Vanderlaan G, Tyurina OV, Karlstrom RO, Chandrasekhar A
Citation:
Dev Biol. 2005 Jun 15;282(2):550-70.
Epub:
Not Epub
Abstract:
The Gli family of zinc-finger transcription factors mediates Hedgehog (Hh) signaling in all vertebrates. However, their roles...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Vanderlaan G, Tyurina OV, Karlstrom RO, Chandrasekhar A. Gli function is essential for motor neuron induction in zebrafish. Dev Biol. 2005 Jun 15;282(2):550-70..

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