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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

A critical role for myoglobin in zebrafish development

Authors:
Vlecken DH, Testerink J, Ott EB, Sakalis PA, Jaspers RT, Bagowski CP
Citation:
Int J Dev Biol. 2009 Apr 2. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The globin family, including hemoglobin, myoglobin, neuroglobin and cytoglobin, plays an important role in oxygen storage and...
Organism or Cell Type:
zebrafish
Citation Extract:
Vlecken DH, Testerink J, Ott EB, Sakalis PA, Jaspers RT, Bagowski CP. A critical role for myoglobin in zebrafish development. Int J Dev Biol. 2009 Apr 2. [Epub ahead of print].

A mutation in the RNF170 gene causes autosomal dominant sensory ataxia

Authors:
Valdmanis PN, Dupré N, Lachance M, Stochmanski SJ, Belzil VV, Dion PA, Thiffault I, Brais B, Weston L, Saint-Amant L, Samuels ME, Rouleau GA
Citation:
Brain. 2011 Feb;134(Pt 2):602-7. Epub 2010 Nov 28
Epub:
Not Epub
Abstract:
Autosomal dominant sensory ataxia is a rare genetic condition that results in a progressive ataxia that is caused by...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Valdmanis PN, Dupré N, Lachance M, Stochmanski SJ, Belzil VV, Dion PA, Thiffault I, Brais B, Weston L, Saint-Amant L, Samuels ME, Rouleau GA. A mutation in the RNF170 gene causes autosomal dominant sensory ataxia. Brain. 2011 Feb;134(Pt 2):602-7. Epub 2010 Nov 28.

A novel complex, RUNX1-MYEF2, represses hematopoietic genes in erythroid cells

Authors:
van Riel B, Pakozdi T, Brouwer R, Monteiro R, Tuladhar K, Franke V, Bryne JC, Jorna R, Rijkers EJ, van Ijcken W, Andrieu-Soler C, Demmers J, Patient R, Soler E, Lenhard B, Grosveld F
Citation:
Mol Cell Biol. 2012 Oct;32(19):3814-22. doi: 10.1128/MCB.05938-11. Epub 2012 Jul 16
Epub:
Not Epub
Abstract:
RUNX1 is known to be an essential transcription factor for generating hematopoietic stem cells (HSC), but much less is known...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
van Riel B, Pakozdi T, Brouwer R, Monteiro R, Tuladhar K, Franke V, Bryne JC, Jorna R, Rijkers EJ, van Ijcken W, Andrieu-Soler C, Demmers J, Patient R, Soler E, Lenhard B, Grosveld F. A novel complex, RUNX1-MYEF2, represses hematopoietic genes in erythroid cells. Mol Cell Biol. 2012 Oct;32(19):3814-22. doi: 10.1128/MCB.05938-11. Epub 2012 Jul 16.

A novel mechanism for the transcriptional regulation of Wnt signaling in development

Authors:
Vacik T, Stubbs JL, Lemke G
Citation:
Genes Dev. 2011 Sep 1;25(17):1783-95. Epub 2011 Aug 19.
Epub:
Not Epub
Abstract:
Axial patterning of the embryonic brain requires a precise balance between canonical Wnt signaling, which dorsalizes the...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Vacik T, Stubbs JL, Lemke G. A novel mechanism for the transcriptional regulation of Wnt signaling in development. Genes Dev. 2011 Sep 1;25(17):1783-95. Epub 2011 Aug 19..

A Spatial and Temporal Gradient of Fgf Differentially Regulates Distinct Stages of Neural Development in the Zebrafish Inner Ear

Authors:
Vemaraju S, Kantarci H, Padanad MS, Riley BB
Citation:
PLoS Genet. 2012;8(11):e1003068. doi:10.1371/journal.pgen.1003068
Epub:
Not Epub
Abstract:
Neuroblasts of the statoacoustic ganglion (SAG) initially form in the floor of the otic vesicle during a relatively brief...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Vemaraju S, Kantarci H, Padanad MS, Riley BB. A Spatial and Temporal Gradient of Fgf Differentially Regulates Distinct Stages of Neural Development in the Zebrafish Inner Ear. PLoS Genet. 2012;8(11):e1003068. doi:10.1371/journal.pgen.1003068.

A Zebrafish Model For The Shwachman-Diamond Syndrome (SDS)

Authors:
Venkatasubramani N, Mayer AN
Citation:
Pediatr Res. 2008 Apr;63(4):348-52.
Epub:
Not Epub
Abstract:
The Shwachman-Diamond Syndrome (SDS) is characterized by exocrine pancreatic insufficiency, neutrophil defect and skeletal...
Organism or Cell Type:
zebrafish
Citation Extract:
Venkatasubramani N, Mayer AN. A Zebrafish Model For The Shwachman-Diamond Syndrome (SDS). Pediatr Res. 2008 Apr;63(4):348-52..

Aberrant splicing in the ocular albinism type 1 gene (OA1/GPR143) is corrected in vitro by morpholino antisense oligonucleotides

Authors:
Vetrini F, Tammaro R, Bondanza S, Surace EM, Auricchio A, De Luca M, Ballabio A, Marigo V
Citation:
Hum Mutat. 2006 May;27(5):420-6
Epub:
Not Epub
Abstract:
An intronic point mutation was identified in the ocular albinism type 1 (OA1) gene (HUGO symbol, GPR143) in a family with the X...
Delivery Method:
Special Delivery
Organism or Cell Type:
Melanocyte from BA393 and BA399 patients
Citation Extract:
Vetrini F, Tammaro R, Bondanza S, Surace EM, Auricchio A, De Luca M, Ballabio A, Marigo V. Aberrant splicing in the ocular albinism type 1 gene (OA1/GPR143) is corrected in vitro by morpholino antisense oligonucleotides. Hum Mutat. 2006 May;27(5):420-6.

Abrogation of Prostaglandin E2/EP4 Signaling Impairs the Development of rag1+ Lymphoid Precursors in the Thymus of Zebrafish Embryos

Authors:
Villablanca EJ, Pistocchi A, Court FA, Cotelli F, Bordignon C, Allende ML, Traversari C, Russo V
Citation:
J Immunol. 2007 Jul 1;179(1):357-64
Epub:
Not Epub
Abstract:
PGE(2) is involved in a wide variety of physiological and pathological processes; however, deciphering its role in early...
Organism or Cell Type:
zebrafish
Citation Extract:
Villablanca EJ, Pistocchi A, Court FA, Cotelli F, Bordignon C, Allende ML, Traversari C, Russo V. Abrogation of Prostaglandin E2/EP4 Signaling Impairs the Development of rag1+ Lymphoid Precursors in the Thymus of Zebrafish Embryos. J Immunol. 2007 Jul 1;179(1):357-64.

AHR2 knockdown prevents PAH-mediated cardiac toxicity and XRE- and ARE-associated gene induction in zebrafish (Danio rerio)

Authors:
Van Tiem LA, Di Giulio RT
Citation:
Toxicol Appl Pharmacol. 2011 Aug 1;254(3):280-7. Epub 2011 May 10.
Epub:
Not Epub
Abstract:
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants often present in aquatic systems as complex...
Organism or Cell Type:
zebrafish
Citation Extract:
Van Tiem LA, Di Giulio RT. AHR2 knockdown prevents PAH-mediated cardiac toxicity and XRE- and ARE-associated gene induction in zebrafish (Danio rerio). Toxicol Appl Pharmacol. 2011 Aug 1;254(3):280-7. Epub 2011 May 10..

Antiviral activity of morpholino oligomers designed to block various aspects of Equine arteritis virus amplification in cell culture

Authors:
van den Born E, Stein DA, Iversen PL, Snijder EJ
Citation:
J Gen Virol. 2005 Nov;86(Pt 11):3081-90
Epub:
Not Epub
Abstract:
The antiviral efficacy of ten antisense phosphorodiamidate morpholino oligomers (PMOs) directed against Equine arteritis virus...
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: Vero-E6 cells
Citation Extract:
van den Born E, Stein DA, Iversen PL, Snijder EJ. Antiviral activity of morpholino oligomers designed to block various aspects of Equine arteritis virus amplification in cell culture. J Gen Virol. 2005 Nov;86(Pt 11):3081-90.

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