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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Transforming growth factor-beta activation of phosphatidylinositol 3-kinase is independent of Smad2 and Smad3 and regulates fibroblast responses via p21-activated kinase-2

Authors:
Wilkes MC, Mitchell H, Penheiter SG, Dore JJ, Suzuki K, Edens M, Sharma DK, Pagano RE, Leof EB
Citation:
Cancer Res. 2005 Nov 15;65(22):10431-40
Epub:
Not Epub
Abstract:
Transforming growth factor-beta (TGF-beta) stimulates cellular proliferation and transformation to a myofibroblast phenotype in...
Delivery Method:
LipofectAMINE
Organism or Cell Type:
cell culture: human fibroblasts
Citation Extract:
Wilkes MC, Mitchell H, Penheiter SG, Dore JJ, Suzuki K, Edens M, Sharma DK, Pagano RE, Leof EB. Transforming growth factor-beta activation of phosphatidylinositol 3-kinase is independent of Smad2 and Smad3 and regulates fibroblast responses via p21-activated kinase-2. Cancer Res. 2005 Nov 15;65(22):10431-40.

Transient axonal glycoprotein-1 (TAG-1) and laminin-alpha1 regulate dynamic growth cone behaviors and initial axon direction in vivo

Authors:
Wolman MA, Sittaramane VK, Essner JJ, Yost HJ, Chandrasekhar A, Halloran MC
Citation:
Neural Develop. 2008 Feb 20;3:6
Epub:
Not Epub
Abstract:
BACKGROUND: How axon guidance signals regulate growth cone behavior and guidance decisions in the complex in vivo environment...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wolman MA, Sittaramane VK, Essner JJ, Yost HJ, Chandrasekhar A, Halloran MC. Transient axonal glycoprotein-1 (TAG-1) and laminin-alpha1 regulate dynamic growth cone behaviors and initial axon direction in vivo. Neural Develop. 2008 Feb 20;3:6.

Treatment of highly pathogenic filovirus infections using advanced antisense technology

Authors:
Warren T, Warfield K, Wells J, Swenson D, Lovejoy C, Iversen P, Bavari S.
Citation:
Retrovirology. 2010; 7(Suppl 1): P4. Published online 2010 May 11. doi: 10.1186/1742-4690-7-S1-P4
Epub:
Not Epub
Abstract:
Filoviruses, comprised of the Ebola viruses (EBOV) and Marburg virus (MARV), are highly pathogenic agents with human case...
Delivery Method:
Injection
Organism or Cell Type:
mice, guinea pigs, rhesus macaques, cynomolgus macaques
Citation Extract:
Warren T, Warfield K, Wells J, Swenson D, Lovejoy C, Iversen P, Bavari S.. Treatment of highly pathogenic filovirus infections using advanced antisense technology. Retrovirology. 2010; 7(Suppl 1): P4. Published online 2010 May 11. doi: 10.1186/1742-4690-7-S1-P4.

Tumor delivery of antisense oligomer using trastuzumab within a streptavidin nanoparticle

Authors:
Wang Y, Liu X, Chen L, Cheng D, Rusckowski M, Hnatowich DJ
Citation:
Eur J Nucl Med Mol Imaging. 2009 Dec;36(12):1977-86. doi: 10.1007/s00259-009-1201-2
Epub:
Not Epub
Abstract:
PURPOSE: Trastuzumab (Herceptin) is often internalized following binding to Her2+ tumor cells. The objective of this study was...
Link:
http://link.springer.com/article/10.1007%2Fs00259-009-1201-2
Delivery Method:
Nanoparticle
Organism or Cell Type:
cell culture (SUM190, SUM149) and xenografts in mice
Citation Extract:
Wang Y, Liu X, Chen L, Cheng D, Rusckowski M, Hnatowich DJ. Tumor delivery of antisense oligomer using trastuzumab within a streptavidin nanoparticle. Eur J Nucl Med Mol Imaging. 2009 Dec;36(12):1977-86. doi: 10.1007/s00259-009-1201-2.

Twisted gastrulation is required for forebrain specification and cooperates with Chordin to inhibit BMP signaling during X. tropicalis gastrulation

Authors:
Wills A, Harland RM, Khokha MK
Citation:
Dev Biol. 2006 Jan 1;289(1):166-78.
Epub:
Not Epub
Abstract:
In the developing vertebrate embryo, proper dorsal-ventral patterning relies on BMP antagonists secreted by the organizer...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Wills A, Harland RM, Khokha MK. Twisted gastrulation is required for forebrain specification and cooperates with Chordin to inhibit BMP signaling during X. tropicalis gastrulation. Dev Biol. 2006 Jan 1;289(1):166-78..

Uncoupling nicotine mediated motoneuron axonal pathfinding errors and muscle degeneration in zebrafish

Authors:
Welsh L, Tanguay RL, Svoboda KR
Citation:
Toxicol Appl Pharmacol. 2009 May 15;237(1):29-40. Epub 2008 Jul 23
Epub:
Not Epub
Abstract:
Zebrafish embryos offer a unique opportunity to investigate the mechanisms by which nicotine exposure impacts early vertebrate...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Welsh L, Tanguay RL, Svoboda KR. Uncoupling nicotine mediated motoneuron axonal pathfinding errors and muscle degeneration in zebrafish. Toxicol Appl Pharmacol. 2009 May 15;237(1):29-40. Epub 2008 Jul 23.

Use of zebrafish to probe the divergent virulence potentials and toxin requirements of extraintestinal pathogenic Escherichia coli

Authors:
Wiles TJ, Bower JM, Redd MJ, Mulvey MA
Citation:
PLoS Pathog. 2009 Dec;5(12):e1000697. Epub 2009 Dec 18
Epub:
Not Epub
Abstract:
Extraintestinal pathogenic E. coli (ExPEC) cause an array of diseases, including sepsis, neonatal meningitis, and urinary tract...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wiles TJ, Bower JM, Redd MJ, Mulvey MA. Use of zebrafish to probe the divergent virulence potentials and toxin requirements of extraintestinal pathogenic Escherichia coli. PLoS Pathog. 2009 Dec;5(12):e1000697. Epub 2009 Dec 18.

VANGL2 regulates membrane trafficking of MMP14 to control cell polarity and migration

Authors:
Williams BB, Cantrell VA, Mundell NA, Bennett AC, Quick RE, Jessen JR
Citation:
J Cell Sci. 2012 May 1;125(Pt 9):2141-7. doi: 10.1242/jcs.097964. Epub 2012 Feb 22
Epub:
Not Epub
Abstract:
Planar cell polarity (PCP) describes the polarized orientation of cells within the plane of a tissue. Unlike epithelial PCP,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Williams BB, Cantrell VA, Mundell NA, Bennett AC, Quick RE, Jessen JR. VANGL2 regulates membrane trafficking of MMP14 to control cell polarity and migration. J Cell Sci. 2012 May 1;125(Pt 9):2141-7. doi: 10.1242/jcs.097964. Epub 2012 Feb 22.

Vascular cell biology in vivo: a new piscine paradigm?

Authors:
Weinstein BM
Citation:
Trends in Cell Biology Sep 2002;12(9):439-45
Epub:
Not Epub
Abstract:
Understanding how blood vessels form has become increasingly important in recent years yet remains difficult to study. The...
Delivery Method:
not applicable
Organism or Cell Type:
zebrafish
Citation Extract:
Weinstein BM. Vascular cell biology in vivo: a new piscine paradigm?. Trends in Cell Biology Sep 2002;12(9):439-45.

vhnf1 and Fgf signals synergize to specify rhombomere identity in the zebrafish hindbrain

Authors:
Wiellette EL, Sive H
Citation:
Development. 2003 Aug; 130(16): 3821-9
Epub:
Not Epub
Abstract:
Vertebrate hindbrain segmentation is a highly conserved process but the mechanism of rhombomere determination is not well...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wiellette EL, Sive H. vhnf1 and Fgf signals synergize to specify rhombomere identity in the zebrafish hindbrain. Development. 2003 Aug; 130(16): 3821-9.

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