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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Specification of posterior hypothalamic neurons requires coordinated activities of Fezf2, Otp, Sim1a and Foxb1.2
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Citation:
Development. 2013;140:1762-1773. doi:10.1242/dev.085357 Epub:
Not Epub Abstract:
The hypothalamus is a key integrative center in the brain that consists of diverse cell types required for a variety of... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Wolf A, Ryu S. Specification of posterior hypothalamic neurons requires coordinated activities of Fezf2, Otp, Sim1a and Foxb1.2. Development. 2013;140:1762-1773. doi:10.1242/dev.085357 . |
Targeted gene knockdown in zebrafish reveals distinct intraembryonic functions for insulin-like growth factor 2 (IGF-II) signaling
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Citation:
Endocrinology. 2009 Sep;150(9):4366-75. Epub 2009 May 14 Epub:
Not Epub Abstract:
Insulin-like growth factor 2 (IGF-II) is the predominant IGF ligand regulating prenatal growth in all vertebrates, including... Organism or Cell Type:
zebrafish Citation Extract: White YA, Kyle JT, Wood AW. Targeted gene knockdown in zebrafish reveals distinct intraembryonic functions for insulin-like growth factor 2 (IGF-II) signaling. Endocrinology. 2009 Sep;150(9):4366-75. Epub 2009 May 14. |
Targeting nuclear RNA for in vivo correction of myotonic dystrophy
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Citation:
Nature. 2012;488:111-5 doi:10.1038/nature11362 Epub:
Not Epub Abstract:
Antisense oligonucleotides (ASOs) hold promise for gene-specific knockdown in diseases that involve RNA or protein gain-of-... Delivery Method:
Injection then electroporation in vivo Organism or Cell Type:
mice Citation Extract: Wheeler T, Leger AJ, Pandey SK, MacLeod AR, Nakamori M, Cheng SH, Wentworth BM, Bennett CF, Thornton CA. Targeting nuclear RNA for in vivo correction of myotonic dystrophy. Nature. 2012;488:111-5 doi:10.1038/nature11362. |
TBX3 Directs Cell-Fate Decision toward Mesendoderm
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Citation:
Stem Cell Rep. 2013;[Epub ahead of print] doi:10.1016/j.stemcr.2013.08.002 Epub:
Not Epub Abstract:
Cell-fate decisions and pluripotency are dependent on networks of key transcriptional regulators. Recent reports demonstrated... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Weidgang CE, Russell R, Tata PR, Kühl SJ, Illing A, Müller M, Lin Q, Brunner C, Boeckers TM, Bauer K, Kartikasari AER, Guo Y, Radenz M, Bernemann C, Weiß M, Seufferlein T, Zenke M, Iacovino M, Kyba M, Schöler HR, Kühl M, Liebau S, Kleger A. TBX3 Directs Cell-Fate Decision toward Mesendoderm. Stem Cell Rep. 2013;[Epub ahead of print] doi:10.1016/j.stemcr.2013.08.002 . |
Teasing out T-box targets in early mesoderm
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Citation:
Curr Opin Genet Dev. 2008 Sep 5. [Epub ahead of print] Epub:
Not Epub Abstract:
T-box transcription factor genes are widely conserved in metazoan development and widely involved in developmental processes.... Delivery Method:
Not Specific Organism or Cell Type:
Zebrafish (lit. review) Citation Extract: Wardle FC, Papaioannou VE. Teasing out T-box targets in early mesoderm. Curr Opin Genet Dev. 2008 Sep 5. [Epub ahead of print]. |
TGF-beta activation of c-ABL is independent of receptor internalization and regulated by PI3K and PAK2 in mesenchymal cultures
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Citation:
J Biol Chem. 2006 Sep 22;281(38):27846-54. Epub 2006 Jul 24. Epub:
Not Epub Abstract:
Transforming growth factor beta (TGF-beta) modulates a number of cellular phenotypes as divergent as growth stimulation and... Delivery Method:
LipofectAMINE Organism or Cell Type:
Cell Culture: mesenchymal cell Citation Extract: Wilkes MC, Leof EB. TGF-beta activation of c-ABL is independent of receptor internalization and regulated by PI3K and PAK2 in mesenchymal cultures. J Biol Chem. 2006 Sep 22;281(38):27846-54. Epub 2006 Jul 24.. |
The application of complementary luminescent and fluorescent imaging techniques to visualize nuclear and cytoplasmic Ca(2+) -signalling during the in vivo differentiation of slow muscle cells in zebrafish embryos under normal and dystrophic conditions
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Citation:
Clin Exp Pharmacol Physiol. 2011 Aug 8. doi: 10.1111/j.1440-1681.2011.05582.x. [Epub ahead of print] Epub:
Not Epub Abstract:
1. Evidence is accumulating for a role for Ca(2+) signalling in the differentiation and development of embryonic skeletal... Organism or Cell Type:
zebrafish Citation Extract: Webb SE, Cheung CC, Chan CM, Love DR, Miller AL. The application of complementary luminescent and fluorescent imaging techniques to visualize nuclear and cytoplasmic Ca(2+) -signalling during the in vivo differentiation of slow muscle cells in zebrafish embryos under normal and dystrophic conditions. Clin Exp Pharmacol Physiol. 2011 Aug 8. doi: 10.1111/j.1440-1681.2011.05582.x. [Epub ahead of print]. |
The cdx genes and retinoic acid control the positioning and segmentation of the zebrafish pronephros
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Citation:
PLoS Genet. 2007 Oct 19;3(10):1922-38 Epub:
Not Epub Abstract:
Kidney function depends on the nephron, which comprises a blood filter, a tubule that is subdivided into functionally distinct... Organism or Cell Type:
zebrafish Citation Extract: Wingert RA, Selleck R, Yu J, Song HD, Chen Z, Song A, Zhou Y, Thisse B, Thisse C, McMahon AP, Davidson AJ. The cdx genes and retinoic acid control the positioning and segmentation of the zebrafish pronephros. PLoS Genet. 2007 Oct 19;3(10):1922-38. |
The chianti zebrafish mutant provides a model for erythroid-specific disruption of transferrin receptor 1
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Citation:
Development. 2004 Dec;131(24):6225-35 Epub:
Not Epub Abstract:
Iron is a crucial metal for normal development, being required for the production of heme, which is incorporated into... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Wingert RA, Brownlie A, Galloway JL, Dooley K, Fraenkel P, Axe JL, Davidson AJ, Barut B, Noriega L, Sheng X, Zhou Y, Zon LI. The chianti zebrafish mutant provides a model for erythroid-specific disruption of transferrin receptor 1. Development. 2004 Dec;131(24):6225-35. |
The effect of epidermal growth factor receptor antisense morpholino oligomer on non-small cell lung cancer cell line.
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Citation:
Oncol Rep. 2003 Nov-Dec;10(6):1967-71. Epub:
Not Epub Abstract:
Overexpression of the epidermal growth factor receptor (EGFR) has been identified as a common component of various cancer types... Delivery Method:
Scrape Delivery Organism or Cell Type:
cell culture: NCI-H125 human non-small cell lung cancer line Citation Extract: Washio K, Aoe M, Toyooka S, Mushiake H, Tsukuda K, Shimizu N.. The effect of epidermal growth factor receptor antisense morpholino oligomer on non-small cell lung cancer cell line.. Oncol Rep. 2003 Nov-Dec;10(6):1967-71.. |