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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Morpholino oligonucleotides do not participate perfectly in standard Watson-Crick complexes with RNA

Authors:
Xiao G, Wesolowski D, Izadjoo M, Altman S
Citation:
RNA. 2010 Sep 3. [Epub ahead of print]
Epub:
Not Epub
Abstract:
RNase P from E. coli will cleave a RNA at a site designated in a complex with an external guide sequence (EGS). The location of...
Link:
http://rnajournal.cshlp.org/content/16/11/2218.long
Organism or Cell Type:
Cell free systems
Citation Extract:
Xiao G, Wesolowski D, Izadjoo M, Altman S. Morpholino oligonucleotides do not participate perfectly in standard Watson-Crick complexes with RNA. RNA. 2010 Sep 3. [Epub ahead of print].

Morpholino-based gene knockdown screen of novel genes with developmental function in Ciona intestinalis

Authors:
Yamada L, Shoguchi E, Wada S, Kobayashi K, Mochizuki Y, Satou Y, Satoh N
Citation:
Development. 2003 Dec;130(26):6485-95. Epub 2003 Nov 19
Epub:
Not Epub
Abstract:
In the present study, we conducted an extensive analysis to identify novel genes with developmental function among Ciona...
Delivery Method:
Microinjection
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Yamada L, Shoguchi E, Wada S, Kobayashi K, Mochizuki Y, Satou Y, Satoh N. Morpholino-based gene knockdown screen of novel genes with developmental function in Ciona intestinalis. Development. 2003 Dec;130(26):6485-95. Epub 2003 Nov 19.

Mutation of DNA primase causes extensive apoptosis of retinal neurons through the activation of DNA damage checkpoint and tumor suppressor p53

Authors:
Yamaguchi M, Fujimori-Tonou N, Yoshimura Y, Kishi T, Okamoto H, Masai I
Citation:
Development. 2008 Feb 20; [Epub ahead of print]
Epub:
Not Epub
Abstract:
Apoptosis is often observed in developing tissues. However, it remains unclear how the apoptotic pathway is regulated during...
Organism or Cell Type:
zebrafish
Citation Extract:
Yamaguchi M, Fujimori-Tonou N, Yoshimura Y, Kishi T, Okamoto H, Masai I. Mutation of DNA primase causes extensive apoptosis of retinal neurons through the activation of DNA damage checkpoint and tumor suppressor p53. Development. 2008 Feb 20; [Epub ahead of print].

Mutations in gfpt1 and skiv2l2 cause distinct stage-specific defects in larval melanocyte regeneration in zebrafish

Authors:
Yang CT, Hindes AE, Hultman KA, Johnson SL
Citation:
PLoS Genet. 2007 Jun;3(6):e88. Epub 2007 Apr 17
Epub:
Not Epub
Abstract:
The establishment of a single cell type regeneration paradigm in the zebrafish provides an opportunity to investigate the...
Organism or Cell Type:
zebrafish
Citation Extract:
Yang CT, Hindes AE, Hultman KA, Johnson SL. Mutations in gfpt1 and skiv2l2 cause distinct stage-specific defects in larval melanocyte regeneration in zebrafish. PLoS Genet. 2007 Jun;3(6):e88. Epub 2007 Apr 17.

Nanog-like Regulates Endoderm Formation through the Mxtx2-Nodal Pathway

Authors:
Xu C, Fan ZP, Müller P, Fogley R, DiBiase A, Trompouki E, Unternaehrer J, Xiong F, Torregroza I, Evans T, Megason SG, Daley GQ, Schier AF, Young RA, Zon LI
Citation:
Dev Cell. 2012;22(3):625-38, 10.1016/j.devcel.2012.01.003
Epub:
Not Epub
Abstract:
In mammalian embryonic stem cells, the acquisition of pluripotency is dependent on Nanog, but the in vivo analysis of Nanog has...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xu C, Fan ZP, Müller P, Fogley R, DiBiase A, Trompouki E, Unternaehrer J, Xiong F, Torregroza I, Evans T, Megason SG, Daley GQ, Schier AF, Young RA, Zon LI. Nanog-like Regulates Endoderm Formation through the Mxtx2-Nodal Pathway. Dev Cell. 2012;22(3):625-38, 10.1016/j.devcel.2012.01.003.

Nek9 regulates spindle organization and cell cycle progression during mouse oocyte meiosis and its location in early embryo mitosis

Authors:
Yang SW, Gao C, Chen L, Song YL, Zhu JL, Qi ST, Jiang ZZ, Wang ZW, Lin F, Huang H, Xing FQ, Sun QY
Citation:
Cell Cycle. 2012;11(23) [Epub ahead of print]
Epub:
Not Epub
Abstract:
Nek9 (also known as Nercc1), a member of the NIMA (never in mitosis A) family of protein kinases, regulates spindle formation,...
Delivery Method:
Microinjection
Organism or Cell Type:
mouse oocytes
Citation Extract:
Yang SW, Gao C, Chen L, Song YL, Zhu JL, Qi ST, Jiang ZZ, Wang ZW, Lin F, Huang H, Xing FQ, Sun QY. Nek9 regulates spindle organization and cell cycle progression during mouse oocyte meiosis and its location in early embryo mitosis. Cell Cycle. 2012;11(23) [Epub ahead of print].

Neutrophils exert protection in the early tuberculous granuloma by oxidative killing of mycobacteria phagocytosed from infected macrophages

Authors:
Yang CT, Cambier CJ, Davis JM, Hall CJ, Crosier PS, Ramakrishnan L
Citation:
Cell Host Microbe. 2012 Sep 13;12(3):301-12. doi: 10.1016/j.chom.2012.07.009
Epub:
Not Epub
Abstract:
Neutrophils are typically the first responders in host defense against invading pathogens, which they destroy by both oxidative...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang CT, Cambier CJ, Davis JM, Hall CJ, Crosier PS, Ramakrishnan L. Neutrophils exert protection in the early tuberculous granuloma by oxidative killing of mycobacteria phagocytosed from infected macrophages. Cell Host Microbe. 2012 Sep 13;12(3):301-12. doi: 10.1016/j.chom.2012.07.009.

Notch signaling downstream of foxD5 promotes neural ectodermal transcription factors that inhibit neural differentiation

Authors:
Yan B, Neilson KM, Moody SA
Citation:
Dev Dyn. 2009 Jun;238(6):1358-65
Epub:
Not Epub
Abstract:
We investigated the role of the Notch signaling pathway in regulating several transcription factors that stabilize a neural...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yan B, Neilson KM, Moody SA. Notch signaling downstream of foxD5 promotes neural ectodermal transcription factors that inhibit neural differentiation. Dev Dyn. 2009 Jun;238(6):1358-65.

Ogon/Secreted Frizzled functions as a negative feedback regulator of Bmp signaling

Authors:
Yabe T, Shimizu T, Muraoka O, Bae Y-K, Hirata T, Nojima H, Kawakami A, Hirano T, Hibi M
Citation:
Development. 2003;130, 2705-16
Epub:
Not Epub
Abstract:
The zebrafish mutant ogon (also called mercedes and short tail) displays ventralized phenotypes similar to the chordino (dino)...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yabe T, Shimizu T, Muraoka O, Bae Y-K, Hirata T, Nojima H, Kawakami A, Hirano T, Hibi M. Ogon/Secreted Frizzled functions as a negative feedback regulator of Bmp signaling. Development. 2003;130, 2705-16.

Phosphatidylinositol transfer protein-alpha in netrin-1-induced PLC signalling and neurite outgrowth

Authors:
Xie Y, Ding YQ, Hong Y, Feng Z, Navarre S, Xi CX, Zhu XJ, Wang CL, Ackerman SL, Kozlowski D, Mei L, Xiong WC
Citation:
Nat Cell Biol. 2005 Nov;7(11):1124-32.
Epub:
Not Epub
Abstract:
Neurite extension is essential for wiring the nervous system during development. Although several factors are known to regulate...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xie Y, Ding YQ, Hong Y, Feng Z, Navarre S, Xi CX, Zhu XJ, Wang CL, Ackerman SL, Kozlowski D, Mei L, Xiong WC. Phosphatidylinositol transfer protein-alpha in netrin-1-induced PLC signalling and neurite outgrowth. Nat Cell Biol. 2005 Nov;7(11):1124-32..

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