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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Both DNA topoisomerase II-binding protein 1 and BRCA1 regulate the G2-M cell cycle checkpoint

Authors:
Yamane K, Chen J, Kinsella TJ
Citation:
Cancer Res. 2003 Jun 15;63(12):3049-53
Epub:
Not Epub
Abstract:
Cell cycle checkpoints play a central role in genomic stability. The human DNA topoisomerase II-binding protein 1 (TopBP1)...
Delivery Method:
Electroporation
Organism or Cell Type:
cell culture: human breast carcinoma mutant HCC1937+wtBRCA1
Citation Extract:
Yamane K, Chen J, Kinsella TJ. Both DNA topoisomerase II-binding protein 1 and BRCA1 regulate the G2-M cell cycle checkpoint. Cancer Res. 2003 Jun 15;63(12):3049-53.

Cardiomyopathy in zebrafish due to mutation in an alternatively spliced exon of titin

Authors:
Xu X, Meiler SE, Zhong TP, Mohideen M, Crossley DA, Burggren WW, Fishman MC
Citation:
Nat Genet. 2002 Feb;30(2):205-9
Epub:
Not Epub
Abstract:
The zebrafish embryo is transparent and can tolerate absence of blood flow because its oxygen is delivered by diffusion rather...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xu X, Meiler SE, Zhong TP, Mohideen M, Crossley DA, Burggren WW, Fishman MC. Cardiomyopathy in zebrafish due to mutation in an alternatively spliced exon of titin. Nat Genet. 2002 Feb;30(2):205-9.

Categorical data analysis in experimental biology

Authors:
Xu B, Feng X, Burdine RD
Citation:
Dev Biol. 2010 Dec 1;348(1):3-11. Epub 2010 Sep 6. Review
Epub:
Not Epub
Abstract:
The categorical data set is an important data class in experimental biology and contains data separable into several mutually...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xu B, Feng X, Burdine RD. Categorical data analysis in experimental biology. Dev Biol. 2010 Dec 1;348(1):3-11. Epub 2010 Sep 6. Review.

Ci-Tbx6b and Ci-Tbx6c are key mediators of the maternal effect gene Ci-macho1 in muscle cell differentiation in Ciona intestinalis embryos

Authors:
Yagi K, Takatori N, Satou Y, Satoh N
Citation:
Dev Biol. 2005 Jun 15;282(2):535-49
Epub:
Not Epub
Abstract:
Maternally deposited mRNA encoding the Zic family zinc-finger protein Ci-macho1 is a determinant responsible for muscle cell...
Delivery Method:
Microinjection
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Yagi K, Takatori N, Satou Y, Satoh N. Ci-Tbx6b and Ci-Tbx6c are key mediators of the maternal effect gene Ci-macho1 in muscle cell differentiation in Ciona intestinalis embryos. Dev Biol. 2005 Jun 15;282(2):535-49.

Ciona intestinalis Noto4 contains a phosphotyrosine interaction domain and is involved in the midline intercalation of notochord cells

Authors:
Yamada S, Ueno N, Satoh N, Takahashi H
Citation:
Int J Dev Biol. 2010 Sep 23. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Brachyury plays a pivotal role in the notochord formation in ascidian embryos. Ciona intestinalis Noto4 (Ci-Noto4) was isolated...
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Yamada S, Ueno N, Satoh N, Takahashi H. Ciona intestinalis Noto4 contains a phosphotyrosine interaction domain and is involved in the midline intercalation of notochord cells. Int J Dev Biol. 2010 Sep 23. [Epub ahead of print].

Claudin5 genes encoding tight junction proteins are required for Xenopus heart formation

Authors:
Yamagishi M, Ito Y, Ariizumi T, Komazaki S, Danno H, Michiue T, Asashima M
Citation:
Dev Growth Differ. 2010 Sep;52(7):665-75
Epub:
Not Epub
Abstract:
Claudin proteins are the major components of tight junctions connecting adjacent cells, where they regulate a variety of...
Organism or Cell Type:
Xenopus
Citation Extract:
Yamagishi M, Ito Y, Ariizumi T, Komazaki S, Danno H, Michiue T, Asashima M. Claudin5 genes encoding tight junction proteins are required for Xenopus heart formation. Dev Growth Differ. 2010 Sep;52(7):665-75.

Conformational Changes of a Ca2+-Binding Domain of the Na+ -Ca2+ Exchanger Monitored by FRET in Transgenic Zebrafish Heart

Authors:
Xie Y, Ottolia M, John S, Chen JN, Philipson KD
Citation:
Am J Physiol Cell Physiol. 2008 Jun 11. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The Na(+) -Ca(2+) exchanger is the major Ca(2+) extrusion mechanism in cardiac myocytes. The activity of the cardiac Na(+)-Ca(2...
Organism or Cell Type:
zebrafish
Citation Extract:
Xie Y, Ottolia M, John S, Chen JN, Philipson KD. Conformational Changes of a Ca2+-Binding Domain of the Na+ -Ca2+ Exchanger Monitored by FRET in Transgenic Zebrafish Heart. Am J Physiol Cell Physiol. 2008 Jun 11. [Epub ahead of print].

Cyclic Caged Morpholinos: Conformationally Gated Probes of Embryonic Gene Function

Authors:
Yamazoe S, Shestopalov IA, Provost E, Leach SD, Chen JK
Citation:
Angew Chem Int Ed Engl. 2012 Jun 11. doi: 10.1002/anie.201201690. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Feeling a bit cagey: Morpholino-based antisense reagents have been caged through oligonucleotide cyclization, enabling...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yamazoe S, Shestopalov IA, Provost E, Leach SD, Chen JK. Cyclic Caged Morpholinos: Conformationally Gated Probes of Embryonic Gene Function. Angew Chem Int Ed Engl. 2012 Jun 11. doi: 10.1002/anie.201201690. [Epub ahead of print].

Damage in brain development by morpholino knockdown of zebrafish dax1

Authors:
Yajima Y, Vestergaard MC, Takagi M
Citation:
J Bio Bioeng. 2012;[Epub ahead of print] 10.1016/j.jbiosc.2012.02.002
Epub:
Not Epub
Abstract:
DAX1 is an orphan nuclear receptor and involved in development of steroidogenic organs, which activates transcription of genes...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yajima Y, Vestergaard MC, Takagi M. Damage in brain development by morpholino knockdown of zebrafish dax1. J Bio Bioeng. 2012;[Epub ahead of print] 10.1016/j.jbiosc.2012.02.002.

Depletion of Bhmt Elevates sonic hedgehog Transcript Level and Increases beta-Cell Number in Zebrafish

Authors:
Yang SL, Aw SS, Chang C, Korzh S, Korzh V, Peng J
Citation:
Endocrinology. 2011 Sep 27. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Betaine homocysteine S-methyltransferase (BHMT, EC 2.1.1.5) is a key enzyme in the methionine cycle and is highly expressed in...
Organism or Cell Type:
zebrafish
Citation Extract:
Yang SL, Aw SS, Chang C, Korzh S, Korzh V, Peng J. Depletion of Bhmt Elevates sonic hedgehog Transcript Level and Increases beta-Cell Number in Zebrafish. Endocrinology. 2011 Sep 27. [Epub ahead of print].

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