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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Bubble Liposomes and Ultrasound Exposure Improve Localized Morpholino Oligomer Delivery into the Skeletal Muscles of Dystrophic mdx Mice

Authors:
Negishi Y, Ishii Y, Shiono H, Akiyama S, Sekine S, Kojima T, Mayama S, Kikuchi T, Hamano N, Endo-Takahashi Y, Suzuki R, Maruyama K, Aramaki Y
Citation:
Molec Pharmaceutics. 2014;[epub ahead of print] doi:10.1021/mp4004755
Epub:
Yes
Abstract:
Duchenne muscular dystrophy (DMD) is a genetic disorder that is caused by mutations in the DMD gene that lead to an absence of...
Link:
http://pubs.acs.org/doi/abs/10.1021/mp4004755
Delivery Method:
bubble liposomes & ultrasound
Organism or Cell Type:
mice, mdx
Citation Extract:
Negishi Y, Ishii Y, Shiono H, Akiyama S, Sekine S, Kojima T, Mayama S, Kikuchi T, Hamano N, Endo-Takahashi Y, Suzuki R, Maruyama K, Aramaki Y. Bubble Liposomes and Ultrasound Exposure Improve Localized Morpholino Oligomer Delivery into the Skeletal Muscles of Dystrophic mdx Mice. Molec Pharmaceutics. 2014;[epub ahead of print] doi:10.1021/mp4004755.

Kctd10 regulates heart morphogenesis by repressing the transcriptional activity of Tbx5a in zebrafish

Authors:
Tong X, Zu Y, Li Z, Li W, Ying L, Yang J, Wang X, He S, Liu D, Zhu Z, Chen J, Lin S, Zhang B
Citation:
Nat Commun. 2014 Jan 16;5:3153. doi: 10.1038/ncomms4153
Epub:
Not Epub
Abstract:
The T-box transcription factor Tbx5 (Tbx5a in zebrafish) plays a crucial role in the formation of cardiac chambers in a dose-...
Link:
http://www.nature.com/ncomms/2014/140116/ncomms4153/full/ncomms4153.html#abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tong X, Zu Y, Li Z, Li W, Ying L, Yang J, Wang X, He S, Liu D, Zhu Z, Chen J, Lin S, Zhang B. Kctd10 regulates heart morphogenesis by repressing the transcriptional activity of Tbx5a in zebrafish. Nat Commun. 2014 Jan 16;5:3153. doi: 10.1038/ncomms4153.

Hypoxia-inducible factor 2α regulates key neutrophil functions in humans, mice and zebrafish

Authors:
Thompson AA, Elks PM, Marriott HM, Eamsamarng S, Higgins KR, Lewis A, Williams L, Parmar S, Shaw G, McGrath EE, Formenti F, Van Eeden FJ, Kinnula VL, Pugh CW, Sabroe I, Dockrell DH, Chilvers ER, Robbins PA, Percy MJ, Simon MC, Johnson RS, Renshaw SA, Whyte MK, Walmsley SR
Citation:
Blood. 2013 Nov 6. [Epub ahead of print]
Epub:
Yes
Abstract:
Neutrophil (PMN) lifespan and function are regulated by hypoxia, via components of the HIF/VHL/hydroxylase pathway, including...
Link:
http://bloodjournal.hematologylibrary.org/content/123/3/366.full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Thompson AA, Elks PM, Marriott HM, Eamsamarng S, Higgins KR, Lewis A, Williams L, Parmar S, Shaw G, McGrath EE, Formenti F, Van Eeden FJ, Kinnula VL, Pugh CW, Sabroe I, Dockrell DH, Chilvers ER, Robbins PA, Percy MJ, Simon MC, Johnson RS, Renshaw SA, Whyte MK, Walmsley SR. Hypoxia-inducible factor 2α regulates key neutrophil functions in humans, mice and zebrafish. Blood. 2013 Nov 6. [Epub ahead of print].

Serum and Glucocorticoid-Regulated Kinase 1 Regulates Neutrophil Clearance during Inflammation Resolution

Authors:
Burgon J, Robertson AL, Sadiku P, Wang X, Hooper-Greenhill E, Prince LR, Walker P, Hoggett EE, Ward JR, Farrow SN, Zuercher WJ, Jeffrey P, Savage CO, Ingham PW, Hurlstone AF, Whyte MKB, Renshaw SA
Citation:
J Immunol. 2014;[Epub ahead of print] doi:10.4049/jimmunol.1300087
Epub:
Yes
Abstract:
The inflammatory response is integral to maintaining health by functioning to resist microbial infection and repair tissue...
Link:
http://www.jimmunol.org/content/early/2014/01/12/jimmunol.1300087.abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Burgon J, Robertson AL, Sadiku P, Wang X, Hooper-Greenhill E, Prince LR, Walker P, Hoggett EE, Ward JR, Farrow SN, Zuercher WJ, Jeffrey P, Savage CO, Ingham PW, Hurlstone AF, Whyte MKB, Renshaw SA. Serum and Glucocorticoid-Regulated Kinase 1 Regulates Neutrophil Clearance during Inflammation Resolution. J Immunol. 2014;[Epub ahead of print] doi:10.4049/jimmunol.1300087.

40LoVe and Samba Are Involved in Xenopus Neural Development and Functionally Distinct from hnRNP AB

Authors:
Andreou M, Yan CYI, Skourides PA
Citation:
PLoS ONE. 2014;9(1):e85026. doi:10.1371/journal.pone.0085026
Epub:
Not Epub
Abstract:
Heterogeneous nuclear ribonucleoproteins (hnRNPs) comprise a large group of modular RNA-binding proteins classified according...
Link:
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0085026
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Andreou M, Yan CYI, Skourides PA. 40LoVe and Samba Are Involved in Xenopus Neural Development and Functionally Distinct from hnRNP AB. PLoS ONE. 2014;9(1):e85026. doi:10.1371/journal.pone.0085026.

Elavl1a regulates zebrafish erythropoiesis via post-transcriptional control of gata1

Authors:
Li X, Lu YC, Dai K, Torregroza I, Hla T, Evans T
Citation:
Blood. 2014 Feb 27;123(9):1384-92. doi: 10.1182/blood-2013-09-526962. Epub 2014 Jan 14
Epub:
Not Epub
Abstract:
The RNA-binding protein Elavl1 (also know as HuR) regulates gene expression at the post-transcriptional level. Early embryonic...
Link:
http://bloodjournal.hematologylibrary.org/content/early/2014/01/14/blood-2013-09-526962.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li X, Lu YC, Dai K, Torregroza I, Hla T, Evans T. Elavl1a regulates zebrafish erythropoiesis via post-transcriptional control of gata1. Blood. 2014 Feb 27;123(9):1384-92. doi: 10.1182/blood-2013-09-526962. Epub 2014 Jan 14.

Retinoic Acid Receptor Subtype-Specific Transcriptotypes in the Early Zebrafish Embryo

Authors:
Samarut E, Gaudin C, Hughes S, Gillet B, de Bernard S, Jouve PE, Buffat L, Allot A, Lecompte O, Berekelya L, Rochette-Egly C, Laudet V
Citation:
Mol Endocrinol. 2014 Jan 9:me20131358. [Epub ahead of print]
Epub:
Yes
Abstract:
Retinoic acid (RA) controls many aspects of embryonic development by binding to specific receptors (retinoic acid receptors [...
Link:
http://press.endocrine.org/doi/abs/10.1210/me.2013-1358
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Samarut E, Gaudin C, Hughes S, Gillet B, de Bernard S, Jouve PE, Buffat L, Allot A, Lecompte O, Berekelya L, Rochette-Egly C, Laudet V. Retinoic Acid Receptor Subtype-Specific Transcriptotypes in the Early Zebrafish Embryo. Mol Endocrinol. 2014 Jan 9:me20131358. [Epub ahead of print].

Coordinated genomic control of ciliogenesis and cell movement by RFX2

Authors:
Chung M-I, Kwon T, Tu F, Brooks ER, Gupta R, Meyer M, Baker JC, Marcotte EM, Wallingford JB
Citation:
eLife. 2014; 3: e01439. Published online 2014 January 14. doi: 10.7554/eLife.01439
Epub:
Not Epub
Abstract:
The mechanisms linking systems-level programs of gene expression to discrete cell biological processes in vivo remain poorly...
Link:
http://elife.elifesciences.org/content/3/e01439.full
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chung M-I, Kwon T, Tu F, Brooks ER, Gupta R, Meyer M, Baker JC, Marcotte EM, Wallingford JB. Coordinated genomic control of ciliogenesis and cell movement by RFX2. eLife. 2014; 3: e01439. Published online 2014 January 14. doi: 10.7554/eLife.01439.

Profiling, Bioinformatic, and Functional Data on the Developing Olfactory/GnRH System Reveal Cellular and Molecular Pathways Essential for This Process and Potentially Relevant for the Kallmann Syndrome

Authors:
Garaffo G, Provero P, Molineris I, Pinciroli P, Peano C, Battaglia C, Tomaiuolo D, Etzion T, Gothilf Y, Santoro M, Merlo GR
Citation:
Front Endocrinol (Lausanne). 2013;4:203. doi:10.3389/fendo.2013.00203
Epub:
Not Epub
Abstract:
During embryonic development, immature neurons in the olfactory epithelium (OE) extend axons through the nasal mesenchyme, to...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876029/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Garaffo G, Provero P, Molineris I, Pinciroli P, Peano C, Battaglia C, Tomaiuolo D, Etzion T, Gothilf Y, Santoro M, Merlo GR. Profiling, Bioinformatic, and Functional Data on the Developing Olfactory/GnRH System Reveal Cellular and Molecular Pathways Essential for This Process and Potentially Relevant for the Kallmann Syndrome. Front Endocrinol (Lausanne). 2013;4:203. doi:10.3389/fendo.2013.00203.

PRPF4 Mutations Cause Autosomal Dominant Retinitis Pigmentosa

Authors:
Chen X, Liu Y, Sheng X, Tam PO, Zhao K, Chen X, Rong W, Liu Y, Liu X, Pan X, Chen LJ, Zhao Q, Vollrath D, Pang CP, Zhao C
Citation:
Hum Mol Genet. 2014 Jan 12. [Epub ahead of print]
Epub:
Yes
Abstract:
Retinitis pigmentosa (RP), a disease characterized by progressive loss of photoreceptors, exhibits significant genetic...
Link:
http://hmg.oxfordjournals.org/content/early/2014/01/12/hmg.ddu005.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen X, Liu Y, Sheng X, Tam PO, Zhao K, Chen X, Rong W, Liu Y, Liu X, Pan X, Chen LJ, Zhao Q, Vollrath D, Pang CP, Zhao C. PRPF4 Mutations Cause Autosomal Dominant Retinitis Pigmentosa. Hum Mol Genet. 2014 Jan 12. [Epub ahead of print].

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