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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Gne depletion during zebrafish development impairs skeletal muscle structure and function
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Citation:
Hum Mol Genet. 2014 Jan 31. [Epub ahead of print] Epub:
Yes Abstract:
GNE Myopathy is a rare recessively inherited neuromuscular disorder caused by mutations in the GNE gene, which codes for the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Daya A, Vatine GD, Becker-Cohen M, Tal-Goldberg T, Gothilf Y, Du SJ, Mitrani-Rosenbaum S. Gne depletion during zebrafish development impairs skeletal muscle structure and function. Hum Mol Genet. 2014 Jan 31. [Epub ahead of print]. |
Adenylate Cyclase 1 (ADCY1) Mutations Cause Recessive Hearing Impairment in Humans and Defects in Hair Cell Function and Hearing in Zebrafish
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Citation:
Hum Mol Genet. 2014 Jan 29. [Epub ahead of print] Epub:
Yes Abstract:
Cyclic AMP (cAMP) production, which is important for mechanotransduction within the inner ear, is catalyzed by adenylate... Organism or Cell Type:
zebrafish Citation Extract: Santos-Cortez RL, Lee K, Giese AP, Ansar M, Amin-Ud-Din M, Rehn K, Wang X, Aziz A, Chiu I, Ali RH, Smith JD; University of Washington Center for Mendelian Genomics, Shendure J, Bamshad M, Nickerson DA, Ahmed ZM, Ahmad W, Riazuddin S, Leal SM. Adenylate Cyclase 1 (ADCY1) Mutations Cause Recessive Hearing Impairment in Humans and Defects in Hair Cell Function and Hearing in Zebrafish. Hum Mol Genet. 2014 Jan 29. [Epub ahead of print]. |
C2orf62 and TTC17 Are Involved in Actin Organization and Ciliogenesis in Zebrafish and Human
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Citation:
PLoS One. 2014 Jan 27;9(1):e86476. doi: 10.1371/journal.pone.0086476. eCollection 2014 Epub:
Not Epub Abstract:
Vertebrate genomes contain around 20,000 protein-encoding genes, of which a large fraction is still not associated with... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bontems F, Fish RJ, Borlat I, Lembo F, Chocu S, Chalmel F, Borg JP, Pineau C, Neerman-Arbez M, Bairoch A, Lane L. C2orf62 and TTC17 Are Involved in Actin Organization and Ciliogenesis in Zebrafish and Human. PLoS One. 2014 Jan 27;9(1):e86476. doi: 10.1371/journal.pone.0086476. eCollection 2014. |
Knockdown of type 3 iodothyronine deiodinase severely perturbs both embryonic and early larval development in zebrafish
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Citation:
Endocrinology. 2014 Jan 27:en20131660. [Epub ahead of print] Epub:
Not Epub Abstract:
Exposure to appropriate levels of thyroid hormones (THs) at the right time is of key importance for normal development in all... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Heijlen M, Houbrechts AM, Bagci E, Van Herck SL, Kersseboom S, Esguerra CV, Blust R, Visser TJ, Knapen D, Darras VM. Knockdown of type 3 iodothyronine deiodinase severely perturbs both embryonic and early larval development in zebrafish. Endocrinology. 2014 Jan 27:en20131660. [Epub ahead of print]. |
Plakophilin-3 Catenin Associates with the ETV1/ER81 Transcription Factor to Positively Modulate Gene Activity
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Citation:
PLoS ONE. 2014;9(1):e86784. doi:10.1371/journal.pone.0086784 Epub:
Not Epub Abstract:
Members of the plakophilin-catenin sub-family (Pkp-1, -2, and -3) facilitate the linkage of desmosome junctional components to... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Munoz WA, Lee M, Miller RK, Ahmed Z, Ji H, Link TM, Lee GR, Kloc M, Ladbury JE, McCrea PD. Plakophilin-3 Catenin Associates with the ETV1/ER81 Transcription Factor to Positively Modulate Gene Activity. PLoS ONE. 2014;9(1):e86784. doi:10.1371/journal.pone.0086784. |
The function of DrPax1b gene in the embryonic development of zebrafish
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Citation:
Genes Genet Syst. 2013;88(4):261-9 Epub:
Not Epub Abstract:
Vertebrate Pax1 gene is a member of Pax gene family and encodes a transcription factor associated with crucial roles in the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu X, Wang H, Li G, Huang HZ, Wang YQ. The function of DrPax1b gene in the embryonic development of zebrafish. Genes Genet Syst. 2013;88(4):261-9. |
Vascular endothelial growth factor signaling regulates the segregation of artery and vein via ERK activity during vascular development
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Citation:
Biochem Biophys Res Commun. 2013 Jan 25;430(4):1212-6. doi: 10.1016/j.bbrc.2012.12.076. Epub 2012 Dec 22 Epub:
Not Epub Abstract:
Segregation of two axial vessels, the dorsal aorta and caudal vein, is one of the earliest patterning events occur during... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kim SH, Schmitt CE, Woolls MJ, Holland MB, Kim JD, Jin SW. Vascular endothelial growth factor signaling regulates the segregation of artery and vein via ERK activity during vascular development. Biochem Biophys Res Commun. 2013 Jan 25;430(4):1212-6. doi: 10.1016/j.bbrc.2012.12.076. Epub 2012 Dec 22. |
Essential role of AWP1 in neural crest specification in Xenopus
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Citation:
Int J Dev Biol. 2014;[Epub ahead of print] doi:10.1387/ijdb.130109sc Epub:
Yes Abstract:
The neural crest (NC) comprises a transient and multipotent embryonic cell population, which gives rise to a wide variety of... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Seo J-H, Park D-S, Hong M, Chang E-J, Choi S-C. Essential role of AWP1 in neural crest specification in Xenopus. Int J Dev Biol. 2014;[Epub ahead of print] doi:10.1387/ijdb.130109sc. |
Novel Ex Vivo Culture Method for the Study of Dupuytren's Disease: Effects of TGFβ Type 1 Receptor Modulation by Antisense Oligonucleotides
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Citation:
Mol Ther Nucleic Acids. 2014 Jan 21;3:e142. doi: 10.1038/mtna.2013.69 Epub:
Not Epub Abstract:
Dupuytren's disease (DD) is a benign fibroproliferative disease of the hand. It is characterized by the excessive... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Human explant cultures Citation Extract: Karkampouna S, Kruithof BP, Kloen P, Obdeijn MC, van der Laan AM, Tanke HJ, Kemaladewi DU, Hoogaars WM, 't Hoen PA, Aartsma-Rus A, Clark IM, Ten Dijke P, Goumans MJ, Kruithof-de Julio M. Novel Ex Vivo Culture Method for the Study of Dupuytren's Disease: Effects of TGFβ Type 1 Receptor Modulation by Antisense Oligonucleotides. Mol Ther Nucleic Acids. 2014 Jan 21;3:e142. doi: 10.1038/mtna.2013.69. |
Essential role of SH3-domain GRB2-like 3 for vascular lumen maintenance in zebrafish
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Citation:
Arterioscler Thromb Vasc Biol. 2013 Jun;33(6):1280-6. doi: 10.1161/ATVBAHA.112.301025. Epub 2013 Mar 28 Epub:
Not Epub Abstract:
OBJECTIVE: Studying the underlying molecular mechanisms for maintaining stereotyped vascular lumen diameters should help toward... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhao Y, Lin S. Essential role of SH3-domain GRB2-like 3 for vascular lumen maintenance in zebrafish. Arterioscler Thromb Vasc Biol. 2013 Jun;33(6):1280-6. doi: 10.1161/ATVBAHA.112.301025. Epub 2013 Mar 28. |