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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Development of oculomotor circuitry independent of hox3 genes

Authors:
Ma LH, Grove CL, Baker R
Citation:
Nat Commun. 2014 Jun 25;5:4221. doi: 10.1038/ncomms5221
Epub:
Not Epub
Abstract:
Hox genes have been shown to be essential in vertebrate neural circuit formation and their depletion has resulted in homeotic...
Link:
http://www.nature.com/ncomms/2014/140625/ncomms5221/full/ncomms5221.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ma LH, Grove CL, Baker R. Development of oculomotor circuitry independent of hox3 genes. Nat Commun. 2014 Jun 25;5:4221. doi: 10.1038/ncomms5221.

Aciculin interacts with filamin C and Xin and is essential for myofibril assembly, remodeling and maintenance

Authors:
Molt S, Bührdel JB, Yakovlev S, Schein P, Orfanos Z, Kirfel G, Winter L, Wiche G, van der Ven PF, Rottbauer W, Just S, Belkin AM, Fürst DO
Citation:
J Cell Sci. 2014 Jun 24. pii: jcs.152157. [Epub ahead of print]
Epub:
Yes
Abstract:
Filamin C (FLNc) and Xin actin-binding repeat-containing proteins (XIRPs) are multi-adapter proteins mainly expressed in...
Link:
http://jcs.biologists.org/content/early/2014/06/22/jcs.152157.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Molt S, Bührdel JB, Yakovlev S, Schein P, Orfanos Z, Kirfel G, Winter L, Wiche G, van der Ven PF, Rottbauer W, Just S, Belkin AM, Fürst DO. Aciculin interacts with filamin C and Xin and is essential for myofibril assembly, remodeling and maintenance. J Cell Sci. 2014 Jun 24. pii: jcs.152157. [Epub ahead of print].

Nom1 mediates pancreas development by regulating ribosome biogenesis in zebrafish

Authors:
Qin W, Chen Z, Zhang Y, Yan R, Yan G, Li S, Zhong H, Lin S
Citation:
PLoS One. 2014 Jun 26;9(6):e100796. doi: 10.1371/journal.pone.0100796. eCollection 2014
Epub:
Not Epub
Abstract:
Ribosome biogenesis is an important biological process for proper cellular function and development. Defects leading to...
Link:
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0100796
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Qin W, Chen Z, Zhang Y, Yan R, Yan G, Li S, Zhong H, Lin S. Nom1 mediates pancreas development by regulating ribosome biogenesis in zebrafish. PLoS One. 2014 Jun 26;9(6):e100796. doi: 10.1371/journal.pone.0100796. eCollection 2014.

Studying Apoptosis in the Zebrafish

Authors:
Eimon PM
Citation:
Methods Enzymol. 2014;544C:395-431. doi: 10.1016/B978-0-12-417158-9.00016-9
Epub:
Not Epub
Abstract:
Zebrafish (Danio rerio) have been extensively used to study apoptotic cell death during normal development and under a wide...
Link:
http://www.sciencedirect.com/science/article/pii/B9780124171589000169
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Eimon PM. Studying Apoptosis in the Zebrafish. Methods Enzymol. 2014;544C:395-431. doi: 10.1016/B978-0-12-417158-9.00016-9.

NADPH Oxidase 4 Induces Cardiac Arrhythmic Phenotype in Zebrafish

Authors:
Zhang Y, Shimizu H, Siu KL, Mahajan A, Chen JN, Cai H
Citation:
J Biol Chem. 2014 Jun 24. pii: jbc.M114.587196. [Epub ahead of print]
Epub:
Yes
Abstract:
Oxidative stress has been implicated in cardiac arrhythmia, although a causal relationship remains undefined. We have recently...
Link:
http://www.jbc.org/content/early/2014/06/24/jbc.M114.587196
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Y, Shimizu H, Siu KL, Mahajan A, Chen JN, Cai H. NADPH Oxidase 4 Induces Cardiac Arrhythmic Phenotype in Zebrafish. J Biol Chem. 2014 Jun 24. pii: jbc.M114.587196. [Epub ahead of print].

Impaired functional communication between the L-type calcium channel and mitochondria contributes to metabolic inhibition in the mdx heart

Authors:
Viola HM, Adams AM, Davies SM, Fletcher S, Filipovska A, Hool LC
Citation:
Proc Natl Acad Sci U S A. 2014 Jun 26. pii: 201402544. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy is a fatal X-linked disease characterized by the absence of dystrophin. Approximately 20% of boys...
Link:
http://www.pnas.org/content/early/2014/06/25/1402544111.abstract
Delivery Method:
injection
Organism or Cell Type:
mdx mice
Citation Extract:
Viola HM, Adams AM, Davies SM, Fletcher S, Filipovska A, Hool LC. Impaired functional communication between the L-type calcium channel and mitochondria contributes to metabolic inhibition in the mdx heart. Proc Natl Acad Sci U S A. 2014 Jun 26. pii: 201402544. [Epub ahead of print].

The Serine-Threonine Protein Kinase PAK4 Is Dispensable in Zebrafish: Identification of a Morpholino-Generated Pseudophenotype

Authors:
Law SH, Sargent TD
Citation:
PLoS One. 2014 Jun 19;9(6):e100268. doi: 10.1371/journal.pone.0100268. eCollection 2014
Epub:
Not Epub
Abstract:
TALEN-based inactivation of the zebrafish pak4 gene resulted in embryos and adult fish that appear normal and fertile. This is...
Link:
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0100268
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Law SH, Sargent TD. The Serine-Threonine Protein Kinase PAK4 Is Dispensable in Zebrafish: Identification of a Morpholino-Generated Pseudophenotype. PLoS One. 2014 Jun 19;9(6):e100268. doi: 10.1371/journal.pone.0100268. eCollection 2014.

S1P1 inhibits sprouting angiogenesis during vascular development

Authors:
Ben Shoham A, Malkinson G, Krief S, Shwartz Y, Ely Y, Ferrara N, Yaniv K, Zelzer E
Citation:
Development. 2012 Oct;139(20):3859-69. Epub 2012 Sep 5
Epub:
Not Epub
Abstract:
Coordination between the vascular system and forming organs is essential for proper embryonic development. The vasculature...
Link:
http://dev.biologists.org/content/139/20/3859.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ben Shoham A, Malkinson G, Krief S, Shwartz Y, Ely Y, Ferrara N, Yaniv K, Zelzer E. S1P1 inhibits sprouting angiogenesis during vascular development. Development. 2012 Oct;139(20):3859-69. Epub 2012 Sep 5.

Exon skipping restores dystrophin expression, but fails to prevent disease progression in later stage dystrophic dko mice

Authors:
Wu C, Cloer C, Lu P, Milazi S, Shaban M, Shah SN, Marston-Poe L, Moulton HM, Lu QL
Citation:
Gene Ther. 2014;[Epub ahead of print] doi:10.1038/gt.2014.53
Epub:
Yes
Abstract:
Antisense therapy with both chemistries of phosphorodiamidate morpholino oligomers (PMOs) and 2′-O-methyl phosphorothioate has...
Link:
http://www.nature.com/gt/journal/vaop/ncurrent/full/gt201453a.html
Delivery Method:
injection
Organism or Cell Type:
utrophin-dystrophin double KO mice
Citation Extract:
Wu C, Cloer C, Lu P, Milazi S, Shaban M, Shah SN, Marston-Poe L, Moulton HM, Lu QL. Exon skipping restores dystrophin expression, but fails to prevent disease progression in later stage dystrophic dko mice. Gene Ther. 2014;[Epub ahead of print] doi:10.1038/gt.2014.53 .

Distinct Innate Immune Phagocyte Responses to Aspergillus fumigatus Conidia and Hyphae in Zebrafish Larvae

Authors:
Knox BP, Deng Q, Rood M, Eickhoff JC, Keller NP, Huttenlocher A
Citation:
Eukaryot Cell. 2014 Oct;13(10):1266-77. doi: 10.1128/EC.00080-14. Epub 2014 May 30.
Epub:
Yes
Abstract:
Aspergillus fumigatus is the most common filamentous fungal pathogen of immunocompromised hosts resulting in invasive...
Link:
http://ec.asm.org/content/early/2014/05/26/EC.00080-14.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Knox BP, Deng Q, Rood M, Eickhoff JC, Keller NP, Huttenlocher A. Distinct Innate Immune Phagocyte Responses to Aspergillus fumigatus Conidia and Hyphae in Zebrafish Larvae. Eukaryot Cell. 2014 Oct;13(10):1266-77. doi: 10.1128/EC.00080-14. Epub 2014 May 30..

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