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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

In Vivo Imaging of Transgenic Gene Expression in Individual Retinal Progenitors in Chimeric Zebrafish Embryos to Study Cell Nonautonomous Influences

Authors:
Dudczig S, Currie PD, Poggi L, Jusuf PR
Citation:
J Vis Exp. 2017 Mar 22;(121). doi: 10.3791/55490
Epub:
Not Epub
Abstract:
The genetic and technical strengths have made the zebrafish vertebrate a key model organism in which the consequences of gene...
Link:
https://www.jove.com/video/55490/in-vivo-imaging-transgenic-gene-expression-individual-retinal
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dudczig S, Currie PD, Poggi L, Jusuf PR. In Vivo Imaging of Transgenic Gene Expression in Individual Retinal Progenitors in Chimeric Zebrafish Embryos to Study Cell Nonautonomous Influences. J Vis Exp. 2017 Mar 22;(121). doi: 10.3791/55490.

Tropomyosin 1: Multiple roles in the developing heart and in the formation of congenital heart defects

Authors:
England J, Granados-Riveron J, Polo-Parada L, Kuriakose D, Moore C, Brook JD, Rutland CS, Setchfield K, Gell C, Ghosh TK, Bu'Lock F, Thornborough C, Ehler E, Loughna S
Citation:
J Mol Cell Cardiol. 2017 Mar 27;106:1-13. doi: 10.1016/j.yjmcc.2017.03.006. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Tropomyosin 1 (TPM1) is an essential sarcomeric component, stabilising the thin filament and facilitating actin's...
Link:
http://www.sciencedirect.com/science/article/pii/S0022282817300615
Delivery Method:
pluronic gel
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
England J, Granados-Riveron J, Polo-Parada L, Kuriakose D, Moore C, Brook JD, Rutland CS, Setchfield K, Gell C, Ghosh TK, Bu'Lock F, Thornborough C, Ehler E, Loughna S. Tropomyosin 1: Multiple roles in the developing heart and in the formation of congenital heart defects. J Mol Cell Cardiol. 2017 Mar 27;106:1-13. doi: 10.1016/j.yjmcc.2017.03.006. [Epub ahead of print].

Wnt8a expands the pool of embryonic kidney progenitors in zebrafish

Authors:
Naylor RW, Han HI, Hukriede NA, Davidson AJ
Citation:
Dev Biol. 2017 Mar 27. pii: S0012-1606(16)30674-1. doi: 10.1016/j.ydbio.2017.03.027. [Epub ahead of print]
Epub:
Yes
Abstract:
During zebrafish embryogenesis the pronephric kidney arises from a small population of posterior mesoderm cells that then...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160616306741
Organism or Cell Type:
zebrafish
Citation Extract:
Naylor RW, Han HI, Hukriede NA, Davidson AJ. Wnt8a expands the pool of embryonic kidney progenitors in zebrafish. Dev Biol. 2017 Mar 27. pii: S0012-1606(16)30674-1. doi: 10.1016/j.ydbio.2017.03.027. [Epub ahead of print].

Semaphorin4D promotes axon regrowth and swimming ability during recovery following zebrafish spinal cord injury

Authors:
Peng SX, Yao L, Cui C, Zhao HD, Liu CJ, Li YH, Wang LF, Huang SB, Shen YQ
Citation:
Neuroscience. 2017 Mar 25. pii: S0306-4522(17)30196-3. doi: 10.1016/j.neuroscience.2017.03.030. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Semaphorins comprise a family of proteins involved in axon guidance during development. Semaphorin4D (Sema4D) has both...
Link:
http://www.sciencedirect.com/science/article/pii/S0306452217301963
Organism or Cell Type:
zebrafish
Citation Extract:
Peng SX, Yao L, Cui C, Zhao HD, Liu CJ, Li YH, Wang LF, Huang SB, Shen YQ. Semaphorin4D promotes axon regrowth and swimming ability during recovery following zebrafish spinal cord injury. Neuroscience. 2017 Mar 25. pii: S0306-4522(17)30196-3. doi: 10.1016/j.neuroscience.2017.03.030. [Epub ahead of print].

Ultrasensitive Hybridization-Based ELISA Method for the Determination of Phosphorodiamidate Morpholino Oligonucleotides in Biological samples

Authors:
Burki U, Straub V
Citation:
Methods Mol Biol. 2017;1565:265-277. doi: 10.1007/978-1-4939-6817-6_22
Epub:
Not Epub
Abstract:
Determining the concentration of oligonucleotide in biological samples such as tissue lysate and serum is essential for...
Link:
http://www.springer.com/us/book/9781493968152
Citation Extract:
Burki U, Straub V. Ultrasensitive Hybridization-Based ELISA Method for the Determination of Phosphorodiamidate Morpholino Oligonucleotides in Biological samples. Methods Mol Biol. 2017;1565:265-277. doi: 10.1007/978-1-4939-6817-6_22.

Surface Plasmon Resonance-Based Concentration Determination Assay: Label-Free and Antibody-Free Quantification of Morpholinos

Authors:
Boutilier J, Moulton HM
Citation:
Methods Mol Biol. 2017;1565:251-263. doi: 10.1007/978-1-4939-6817-6_21
Epub:
Not Epub
Abstract:
Surface plasmon resonance (SPR) is a physical process that allows label-free and real-time detection of biomolecular...
Link:
http://www.springer.com/us/book/9781493968152
Citation Extract:
Boutilier J, Moulton HM. Surface Plasmon Resonance-Based Concentration Determination Assay: Label-Free and Antibody-Free Quantification of Morpholinos. Methods Mol Biol. 2017;1565:251-263. doi: 10.1007/978-1-4939-6817-6_21.

Delivery of Morpholino Antisense Oligonucleotides to a Developing Ovine Conceptus via Luminal Injection into a Ligated Uterine Horn

Authors:
Wang X, Dunlap KA
Citation:
Methods Mol Biol. 2017;1565:241-250. doi: 10.1007/978-1-4939-6817-6_20
Epub:
Not Epub
Abstract:
In vivo delivery of morpholino antisense oligonucleotides (MAO) directly into the uterine lumen of a peri-implantation period...
Link:
http://www.springer.com/us/book/9781493968152
Delivery Method:
Endo-Porter
Organism or Cell Type:
Ovis aries (sheep)
Citation Extract:
Wang X, Dunlap KA. Delivery of Morpholino Antisense Oligonucleotides to a Developing Ovine Conceptus via Luminal Injection into a Ligated Uterine Horn. Methods Mol Biol. 2017;1565:241-250. doi: 10.1007/978-1-4939-6817-6_20.

Intracerebroventricular Delivery in Mice for Motor Neuron Diseases

Authors:
Nizzardo M, Rizzuti M
Citation:
Methods Mol Biol. 2017;1565:229-239. doi: 10.1007/978-1-4939-6817-6_19
Epub:
Not Epub
Abstract:
The use of antisense oligonucleotides to target specific mRNA sequences represents a promising therapeutic strategy for...
Link:
http://www.springer.com/us/book/9781493968152
Delivery Method:
intracerebroventricular injection
Organism or Cell Type:
mice
Citation Extract:
Nizzardo M, Rizzuti M. Intracerebroventricular Delivery in Mice for Motor Neuron Diseases. Methods Mol Biol. 2017;1565:229-239. doi: 10.1007/978-1-4939-6817-6_19.

In Vivo and Explant Electroporation of Morpholinos in the Developing Mouse Retina

Authors:
Karunakaran DK, Kanadia R
Citation:
Methods Mol Biol. 2017;1565:215-227. doi: 10.1007/978-1-4939-6817-6_18
Epub:
Not Epub
Abstract:
Neonatal in vivo electroporations and retinal explant electroporations have been widely employed in understanding the effects...
Link:
http://www.springer.com/us/book/9781493968152
Delivery Method:
electroporation
Organism or Cell Type:
mice
Citation Extract:
Karunakaran DK, Kanadia R. In Vivo and Explant Electroporation of Morpholinos in the Developing Mouse Retina. Methods Mol Biol. 2017;1565:215-227. doi: 10.1007/978-1-4939-6817-6_18.

Systemic Delivery of Morpholinos to Skip Multiple Exons in a Dog Model of Duchenne Muscular Dystrophy

Authors:
Maruyama R, Echigoya Y, Caluseriu O, Aoki Y, Takeda S, Yokota T
Citation:
Methods Mol Biol. 2017;1565:201-213. doi: 10.1007/978-1-4939-6817-6_17
Epub:
Not Epub
Abstract:
Exon-skipping therapy is an emerging approach that uses synthetic DNA-like molecules called antisense oligonucleotides (AONs)...
Link:
http://www.springer.com/us/book/9781493968152
Delivery Method:
injection, peptide-linked
Organism or Cell Type:
Canis familiaris (dog)
Citation Extract:
Maruyama R, Echigoya Y, Caluseriu O, Aoki Y, Takeda S, Yokota T. Systemic Delivery of Morpholinos to Skip Multiple Exons in a Dog Model of Duchenne Muscular Dystrophy. Methods Mol Biol. 2017;1565:201-213. doi: 10.1007/978-1-4939-6817-6_17.

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