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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Characterization and expression analysis of Galnts in developing Strongylocentrotus purpuratus embryos
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Citation:
PLoS One. 2017 Apr 27;12(4):e0176479. doi: 10.1371/journal.pone.0176479. eCollection 2017 Epub:
Not Epub Abstract:
Mucin-type O-glycosylation is a ubiquitous posttranslational modification in which N-Acetylgalactosamine (GalNAc) is added to... Delivery Method:
microinjection Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin) Citation Extract: Famiglietti AL, Wei Z, Beres TM, Milac AL, Tran DT, Patel D, Angerer RC, Angerer LM, Tabak LA. Characterization and expression analysis of Galnts in developing Strongylocentrotus purpuratus embryos. PLoS One. 2017 Apr 27;12(4):e0176479. doi: 10.1371/journal.pone.0176479. eCollection 2017. |
CLPB mutations cause 3-methylglutaconic aciduria, progressive brain atrophy, intellectual disability, congenital neutropenia, cataracts, movement disorder
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Citation:
Am J Hum Genet. 2015 Feb 5;96(2):245-57. doi: 10.1016/j.ajhg.2014.12.013. Epub 2015 Jan 15 Epub:
Not Epub Abstract:
We studied a group of individuals with elevated urinary excretion of 3-methylglutaconic acid, neutropenia that can develop into... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wortmann SB, Ziętkiewicz S, Kousi M, Szklarczyk R, Haack TB, Gersting SW, Muntau AC, Rakovic A, Renkema GH, Rodenburg RJ, Strom TM, Meitinger T, Rubio-Gozalbo ME, Chrusciel E, Distelmaier F, Golzio C, Jansen JH, van Karnebeek C, Lillquist Y, Lücke T, Õunap K, Zordania R, Yaplito-Lee J, van Bokhoven H, Spelbrink JN, Vaz FM, Pras-Raves M, Ploski R, Pronicka E, Klein C, Willemsen MA, de Brouwer AP, Prokisch H, Katsanis N, Wevers RA.. CLPB mutations cause 3-methylglutaconic aciduria, progressive brain atrophy, intellectual disability, congenital neutropenia, cataracts, movement disorder. Am J Hum Genet. 2015 Feb 5;96(2):245-57. doi: 10.1016/j.ajhg.2014.12.013. Epub 2015 Jan 15. |
Identification of target genes downstream of Semaphorin6A/PlexinA2 signaling in zebrafish
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Citation:
Dev Dyn. 2017 Apr 25. doi: 10.1002/dvdy.24512. [Epub ahead of print] Epub:
Yes Abstract:
BACKGROUND: Semaphorin (Sema)/Plexin (Plxn) signaling is important for many aspects of neuronal development, however the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Emerson SE, St Clair RM, Waldron AL, Bruno SR, Duong A, Driscoll HE, Ballif BA, McFarlane S, Ebert AM. Identification of target genes downstream of Semaphorin6A/PlexinA2 signaling in zebrafish. Dev Dyn. 2017 Apr 25. doi: 10.1002/dvdy.24512. [Epub ahead of print]. |
Functional Manipulation of Maternal Gene Products Using In Vitro Oocyte Maturation in Zebrafish
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Citation:
JoVE. 2017;122:e55213. doi:10.3791/55213 Epub:
Not Epub Abstract:
Cellular events that take place during the earliest stages of animal embryonic development are driven by maternally derived... Link:
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microinjection Organism or Cell Type:
zebrafish Citation Extract: Welch EL, Eno CC, Nair S, Lindeman RE, Pelegri F. Functional Manipulation of Maternal Gene Products Using In Vitro Oocyte Maturation in Zebrafish. JoVE. 2017;122:e55213. doi:10.3791/55213. |
Neurons secrete miR-132-containing exosomes to regulate brain vascular integrity
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Citation:
Cell Res. 2017 Apr 21. doi: 10.1038/cr.2017.62. [Epub ahead of print] Epub:
Yes Abstract:
Vascular integrity helps maintain brain microenvironment homeostasis, which is critical for the normal development and function... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Xu B, Zhang Y, Du XF, Li J, Zi HX, Bu JW, Yan Y, Han H, Du JL. Neurons secrete miR-132-containing exosomes to regulate brain vascular integrity. Cell Res. 2017 Apr 21. doi: 10.1038/cr.2017.62. [Epub ahead of print]. |
CMTM3 (CKLF-Like Marvel Transmembrane Domain 3) Mediates Angiogenesis by Regulating Cell Surface Availability of VE-Cadherin in Endothelial Adherens Junctions
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Citation:
Arterioscler Thromb Vasc Biol. 2017 Jun;37(6):1098-1114. doi: 10.1161/ATVBAHA.116.308792. Epub 2017 Apr 20. PMID: 28428220 Epub:
Yes Abstract:
Objective: Decrease in VE-cadherin adherens junctions reduces vascular stability, whereas disruption of adherens junctions is a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chrifi I, Louzao-Martinez L, Brandt M, van Dijk CGM, Burgisser P, Zhu C, Kros JM, Duncker DJ, Cheng C. CMTM3 (CKLF-Like Marvel Transmembrane Domain 3) Mediates Angiogenesis by Regulating Cell Surface Availability of VE-Cadherin in Endothelial Adherens Junctions. Arterioscler Thromb Vasc Biol. 2017 Jun;37(6):1098-1114. doi: 10.1161/ATVBAHA.116.308792. Epub 2017 Apr 20. PMID: 28428220. |
Ultrasensitive Detection of MicroRNAs with Morpholino-Functionalized Nanochannel Biosensor
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Citation:
Anal Chem. 2017;[Just accepted] doi:10.1021/acs.analchem.7b00487 Epub:
Yes Abstract:
Here we demonstrate a phosphorodiamidate morpholino oligos (PMO)-functionlized nanochannel biosensor for label-free detection... Citation Extract: Liao T, Li X, Tong Q, Zou K, Zhang H, Tang L, Sun Z, Zhang G-J. Ultrasensitive Detection of MicroRNAs with Morpholino-Functionalized Nanochannel Biosensor. Anal Chem. 2017;[Just accepted] doi:10.1021/acs.analchem.7b00487. |
Ex vivo cultures combined with vivo-morpholino induced gene knockdown provide a system to assess the role of WT1 and GATA4 during gonad differentiation
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Citation:
PLoS ONE. 2017;12(4):e0176296. doi:10.1371/journal.pone.0176296 Epub:
Not Epub Abstract:
Gonad morphogenesis relies on the correct spatiotemporal expression of a number of genes that together fulfill the... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mouse gonad explants Citation Extract: Rudigier LJ, Dame C, Scholz H, Kirschner KM. Ex vivo cultures combined with vivo-morpholino induced gene knockdown provide a system to assess the role of WT1 and GATA4 during gonad differentiation. PLoS ONE. 2017;12(4):e0176296. doi:10.1371/journal.pone.0176296. |
Bioenergetic status modulates motor neuron vulnerability and pathogenesis in a zebrafish model of spinal muscular atrophy
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Citation:
PLoS Genet. 2017;[uncorrected proof] doi:10.1371/journal.pgen.1006744 Epub:
Not Epub Abstract:
Degeneration and loss of lower motor neurons is the major pathological hallmark of spinal muscular atrophy (SMA), resulting... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Boyd PJ, Tu W-Y, Shorrock HK, Groen EJN, Carter RN, Powis RA, Thomson SR, Thomson D, Graham LC, Motyl AAL, Wishart TM, Highley JR, Morton NM, Becker T, Becker CG, Heath PR, Gillingwater TH. Bioenergetic status modulates motor neuron vulnerability and pathogenesis in a zebrafish model of spinal muscular atrophy. PLoS Genet. 2017;[uncorrected proof] doi:10.1371/journal.pgen.1006744. |
Molecular regionalization of the developing amphioxus neural tube challenges major partitions of the vertebrate brain
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Citation:
PLoS Biol. 2017;15(4):e2001573. doi:10.1371/journal.pbio.2001573 Epub:
Not Epub Abstract:
All vertebrate brains develop following a common Bauplan defined by anteroposterior (AP) and dorsoventral (DV) subdivisions,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Albuixech-Crespo B, López-Blanch L, Burguera D, Maeso I, Sánchez-Arrones L, Moreno-Bravo JA, Somorjai I, Pascual-Anaya J, Puelles E, Bovolenta P, Garcia-Fernàndez J, Puelles L, Irimia M, Ferran JL. Molecular regionalization of the developing amphioxus neural tube challenges major partitions of the vertebrate brain. PLoS Biol. 2017;15(4):e2001573. doi:10.1371/journal.pbio.2001573. |